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Gga-miR-219b targeting BCL11B suppresses proliferation, migration and invasion of Marek's disease tumor cell MSB1.
Zhao C, Li X, Han B, You Z, Qu L, Liu C, Song J, Lian L, Yang N. Zhao C, et al. Sci Rep. 2017 Jun 26;7(1):4247. doi: 10.1038/s41598-017-04434-w. Sci Rep. 2017. PMID: 28652615 Free PMC article.
Previous miRNAome analysis showed gga-miR-219b was significantly downregulated in MDV-induced lymphoma, and one of its potential target genes, B-cell chronic lymphocytic /lymphoma 11B (BCL11B) was predicted. In this study, we further investigated the function of gga-miR-21 …
Previous miRNAome analysis showed gga-miR-219b was significantly downregulated in MDV-induced lymphoma, and one of its potential target gene …
Chicken gga-miR-103-3p Targets CCNE1 and TFDP2 and Inhibits MDCC-MSB1 Cell Migration.
Han B, Lian L, Li X, Zhao C, Qu L, Liu C, Song J, Yang N. Han B, et al. G3 (Bethesda). 2016 May 3;6(5):1277-85. doi: 10.1534/g3.116.028498. G3 (Bethesda). 2016. PMID: 26935418 Free PMC article.
Furthermore, two target genes of gga-miR-103-3p, cyclin E1 (CCNE1) and transcription factor Dp-2 (E2F dimerization partner 2) (TFDP2), were predicted and validated by luciferase reporter assay, qPCR, and western blot analysis. ...
Furthermore, two target genes of gga-miR-103-3p, cyclin E1 (CCNE1) and transcription factor Dp-2 (E2F dimerization partner 2) (TFDP2), were …
Marek's disease and new approaches to its control.
Zelník V. Zelník V. Acta Virol. 1995 Feb;39(1):53-63. Acta Virol. 1995. PMID: 7572471 Review.
Several factors, including those virus-encoded and host-dependent, affect the course of the disease. Existing vaccination program is based on the use of attenuated strains of MD virus (MDV) serotype 1 and on strains of non-oncogenic serotype 2 (MDV2) and serotype 3 (herpes …
Several factors, including those virus-encoded and host-dependent, affect the course of the disease. Existing vaccination program is …
Acute demyelinating neuropathy in a patient with neurolymphomatosis.
Mahmoud RA, Abrams CK. Mahmoud RA, et al. BMJ Case Rep. 2018 Mar 5;2018:bcr2017222814. doi: 10.1136/bcr-2017-222814. BMJ Case Rep. 2018. PMID: 29507018 Free PMC article.
Autopsy of the sural nerve showed moderately severe distal sensory axonal loss, direct infiltration of the brachial plexus by malignant lymphocytes and demyelination in brachial and lumbar plexus, most prominent in areas of neoplastic infiltration. Based on this patient's cour …
Autopsy of the sural nerve showed moderately severe distal sensory axonal loss, direct infiltration of the brachial plexus by malignant lymp …
Marek's disease is a natural model for lymphomas overexpressing Hodgkin's disease antigen (CD30).
Burgess SC, Young JR, Baaten BJ, Hunt L, Ross LN, Parcells MS, Kumar PM, Tregaskes CA, Lee LF, Davison TF. Burgess SC, et al. Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13879-84. doi: 10.1073/pnas.0305789101. Epub 2004 Sep 8. Proc Natl Acad Sci U S A. 2004. PMID: 15356338 Free PMC article.
CD30 expression by MD virus (MDV)-transformed lymphocytes correlates with expression of the MDV Meq putative oncogene (a c-Jun homologue) in vivo. The chicken CD30 promoter has 15 predicted high-stringency Meq-binding transcription factor recognition motifs, and Meq enhanc …
CD30 expression by MD virus (MDV)-transformed lymphocytes correlates with expression of the MDV Meq putative oncogene (a c-Jun homologue) in …
Modeling the proteome of a Marek's disease transformed cell line: a natural animal model for CD30 overexpressing lymphomas.
Buza JJ, Burgess SC. Buza JJ, et al. Proteomics. 2007 Apr;7(8):1316-26. doi: 10.1002/pmic.200600946. Proteomics. 2007. PMID: 17443643
From the resulting 3870 cellular and 21 MDV proteins we confirm the existence of 3150 "predicted" and 12 "hypothetical" chicken proteins. The UA-01 proteome is proliferative, differentiated, angiogenic, pro-metastatic and pro-immune-escape but anti-programmed cell death, - …
From the resulting 3870 cellular and 21 MDV proteins we confirm the existence of 3150 "predicted" and 12 "hypothetical" chicken prote …
Neurolymphomatosis: a case series of clinical manifestations, treatments, and outcomes.
Kamiya-Matsuoka C, Shroff S, Gildersleeve K, Hormozdi B, Manning JT, Woodman KH. Kamiya-Matsuoka C, et al. J Neurol Sci. 2014 Aug 15;343(1-2):144-8. doi: 10.1016/j.jns.2014.05.058. Epub 2014 Jun 2. J Neurol Sci. 2014. PMID: 24928074
Electrodiagnosis and PET scans were useful diagnostic tools. No factors correlated with poorer prognosis. International collaborative studies will help to better determine the risk factors of NL, response to treatment and outcomes....
Electrodiagnosis and PET scans were useful diagnostic tools. No factors correlated with poorer prognosis. International collaborative …
Congenital contractural arachnodactyly.
Bjerkreim I, Skogland LB, Trygstad O. Bjerkreim I, et al. Acta Orthop Scand. 1976 Jun;47(3):250-3. doi: 10.3109/17453677608991985. Acta Orthop Scand. 1976. PMID: 986113
CCA has often been mistaken for Marfan's disease and arthrogrypois multiplex. Because CCA has a more favourable prognosis, it is very important to be able to recognize this syndrome....
CCA has often been mistaken for Marfan's disease and arthrogrypois multiplex. Because CCA has a more favourable prognosis, it is very …
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