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Quoted phrase not found in phrase index: "Melanoma, cutaneous malignant, susceptibility to, 8"
Page 1
Multiple Sclerosis Treatment and Melanoma Development.
Carbone ML, Lacal PM, Messinese S, De Giglio L, Pozzilli C, Persechino S, Mazzanti C, Failla CM, Pagnanelli G. Carbone ML, et al. Int J Mol Sci. 2020 Apr 22;21(8):2950. doi: 10.3390/ijms21082950. Int J Mol Sci. 2020. PMID: 32331328 Free PMC article. Review.
Therapy of multiple sclerosis (MS) with disease-modifying agents such as natalizumab or fingolimod has been associated with the development of cutaneous melanoma. ...VEGF-A secretion was augmented in one melanoma cell line only after fingolimod treatme …
Therapy of multiple sclerosis (MS) with disease-modifying agents such as natalizumab or fingolimod has been associated with the devel …
Dermoscopic Criteria, Histopathological Correlates and Genetic Findings of Thin Melanoma on Non-Volar Skin.
Massone C, Hofman-Wellenhof R, Chiodi S, Sola S. Massone C, et al. Genes (Basel). 2021 Aug 23;12(8):1288. doi: 10.3390/genes12081288. Genes (Basel). 2021. PMID: 34440462 Free PMC article. Review.
Melanoma genetic markers play a role not only in melanoma susceptibility, initiation, and progression but also in prognosis and therapeutic decisions. ...Particularly, this review will focus on low-CSD (cumulative sun damage) melanoma or superficial sp …
Melanoma genetic markers play a role not only in melanoma susceptibility, initiation, and progression but also in progn …
Germline genomic findings in children and young adults with melanocytic tumors.
Nagel MB, Perrino MR, Nuccio R, Blake AK, Harrison L, Nichols KE, Pappo AS. Nagel MB, et al. Pediatr Blood Cancer. 2023 Jul;70(7):e30361. doi: 10.1002/pbc.30361. Epub 2023 Apr 19. Pediatr Blood Cancer. 2023. PMID: 37073685
In this retrospective study, we examined the prevalence and spectrum of germline variants in selected cancer predisposition genes in 38 children and young adults with melanocytic lesions at St. Jude Children's Research Hospital. Diagnoses included malignant melanoma …
In this retrospective study, we examined the prevalence and spectrum of germline variants in selected cancer predisposition genes in 38 chil …
Targeted Genomic Profiling of Acral Melanoma.
Yeh I, Jorgenson E, Shen L, Xu M, North JP, Shain AH, Reuss D, Wu H, Robinson WA, Olshen A, von Deimling A, Kwok PY, Bastian BC, Asgari MM. Yeh I, et al. J Natl Cancer Inst. 2019 Oct 1;111(10):1068-1077. doi: 10.1093/jnci/djz005. J Natl Cancer Inst. 2019. PMID: 30657954 Free PMC article.
BACKGROUND: Acral melanoma is a rare type of melanoma that affects world populations irrespective of skin color and has worse survival than other cutaneous melanomas. ...RESULTS: In addition to BRAF (21.3%), NRAS (27.9%), and KIT (11.5%) mutations, we identif …
BACKGROUND: Acral melanoma is a rare type of melanoma that affects world populations irrespective of skin color and has worse …
Clinicopathological characteristics and mutation profiling in primary cutaneous melanoma.
Yaman B, Akalin T, Kandiloğlu G. Yaman B, et al. Am J Dermatopathol. 2015 May;37(5):389-97. doi: 10.1097/DAD.0000000000000241. Am J Dermatopathol. 2015. PMID: 25357015
BACKGROUND: The incidence of mutations in malignant melanoma varies remarkably according to the subtype of melanoma, and this in itself is affected by racial and geographical factors. Studies screening melanoma case series for different types of mutati …
BACKGROUND: The incidence of mutations in malignant melanoma varies remarkably according to the subtype of melanoma, an …
Association between a 46-SNP Polygenic Risk Score and melanoma risk in Dutch patients with familial melanoma.
Potjer TP, van der Grinten TWJ, Lakeman IMM, Bollen SH, Rodríguez-Girondo M, Iles MM, Barrett JH, Kiemeney LA, Gruis NA, van Asperen CJ, van der Stoep N. Potjer TP, et al. J Med Genet. 2021 Nov;58(11):760-766. doi: 10.1136/jmedgenet-2020-107251. Epub 2020 Sep 29. J Med Genet. 2021. PMID: 32994281 Free PMC article.
BACKGROUND: Familial clustering of melanoma suggests a shared genetic predisposition among family members, but only 10%-40% of familial cases carry a pathogenic variant in a known high-risk melanoma susceptibility gene. ...CONCLUSION: Our work underlines the …
BACKGROUND: Familial clustering of melanoma suggests a shared genetic predisposition among family members, but only 10%-40% of famili …
A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma.
Teerlink CC, Huff C, Stevens J, Yu Y, Holmen SL, Silvis MR, Trombetti K, Zhao H, Grossman D, Farnham JM, Wen J, Facelli JC, Thomas A, Babst M, Florell SR, Meyer L, Zone JJ, Leachman S, Cannon-Albright LA. Teerlink CC, et al. J Natl Cancer Inst. 2018 Dec 1;110(12):1380-1385. doi: 10.1093/jnci/djy058. J Natl Cancer Inst. 2018. PMID: 29659923 Free PMC article.
Candidate variants were tested for association with melanoma in an independent set of 454 unrelated familial melanoma case subjects and 396 unrelated cancer-free control subjects from Utah, and 1534 melanoma case subjects and 1146 noncancer control subjects f …
Candidate variants were tested for association with melanoma in an independent set of 454 unrelated familial melanoma case sub …
Higher polygenic risk for melanoma is associated with improved survival in a high ultraviolet radiation setting.
Seviiri M, Scolyer RA, Bishop DT, Newton-Bishop JA, Iles MM, Lo SN, Stretch JR, Saw RPM, Nieweg OE, Shannon KF, Spillane AJ, Gordon SD, Olsen CM, Whiteman DC, Landi MT, Thompson JF, Long GV, MacGregor S, Law MH. Seviiri M, et al. J Transl Med. 2022 Sep 5;20(1):403. doi: 10.1186/s12967-022-03613-2. J Transl Med. 2022. PMID: 36064556 Free PMC article.
BACKGROUND: The role of germline genetic factors in determining survival from cutaneous melanoma (CM) is not well understood. OBJECTIVE: To perform a genome-wide association study (GWAS) meta-analysis of melanoma-specific survival (MSS), and test whether a CM …
BACKGROUND: The role of germline genetic factors in determining survival from cutaneous melanoma (CM) is not well understood. …
Clinical and histopathological features of malignant melanoma in germline CDKN2A mutation families.
Måsbäck A, Olsson H, Westerdahl J, Sandberg T, Borg A, Jonsson N, Ingvar C. Måsbäck A, et al. Melanoma Res. 2002 Dec;12(6):549-57. doi: 10.1097/00008390-200212000-00004. Melanoma Res. 2002. PMID: 12459644
Primary cutaneous malignant melanomas (CMMs) from 26 individuals belonging to nine families with an identified mutation were clinically and histopathologically compared with 78 matched CMM controls and with a population-based series of CMMs ( = 667). ...CDKN2A-assoc …
Primary cutaneous malignant melanomas (CMMs) from 26 individuals belonging to nine families with an identified mutation were c …
Plasma proteome alterations by MAPK inhibitors in BRAF(V600)-mutated metastatic cutaneous melanoma.
Babačić H, Eriksson H, Pernemalm M. Babačić H, et al. Neoplasia. 2021 Aug;23(8):783-791. doi: 10.1016/j.neo.2021.06.002. Epub 2021 Jul 8. Neoplasia. 2021. PMID: 34246984 Free PMC article.
Approximately half of metastatic cutaneous melanomas (CM) harbor a mutation in the BRAF protooncogene, upregulating the mitogen-activated protein kinase (MAPK)-pathway. ...
Approximately half of metastatic cutaneous melanomas (CM) harbor a mutation in the BRAF protooncogene, upregulating the mitogen-activ …
34 results