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1977 1
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12 results

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Page 1
Imaging and Clinical Features of Neurocutaneous Melanosis in the Pediatric Population.
Mormina E, Granata F, Vinci SL, Coglitore A, Caragliano AA, Tessitore A, Longo M, Visalli C. Mormina E, et al. Curr Med Imaging. 2021;17(12):1391-1402. doi: 10.2174/1573405617666210527091109. Curr Med Imaging. 2021. PMID: 34047260
Although histological findings are the gold standard for diagnosis confirmation, neuroimaging and clinical features strongly support the suspect of NCM. Localization and extension of the lesions are predictive of neurological manifestations related to increased intracrania …
Although histological findings are the gold standard for diagnosis confirmation, neuroimaging and clinical features strongly support the sus …
Brain Atrophy Associated with Primary Diffuse Meningeal Melanomatosis.
Ma Y, Xing X, Li Y, Ao R, He M, Lan X, Zhao Y, Zhang J, Yu S. Ma Y, et al. World Neurosurg. 2020 Apr;136:311-314. doi: 10.1016/j.wneu.2020.01.164. Epub 2020 Jan 29. World Neurosurg. 2020. PMID: 32004738
BACKGROUND: Primary meningeal melanomatosis is a rare leptomeningeal tumor, and the diagnosis is challenging due to nonspecific clinical symptoms and radiologic findings. ...Immunohistochemical examination of biopsy samples showed that cells were immunopositive for HMB45 a …
BACKGROUND: Primary meningeal melanomatosis is a rare leptomeningeal tumor, and the diagnosis is challenging due to nonspecific clini …
Primary leptomeningeal melanomatosis: early leptomeningeal enhancement on MRI.
Celli P, Acqui M, Trillò G, Ramundo EO, D'Andrea G, Roperto R, Ferrante L. Celli P, et al. J Neurosurg Sci. 2001 Dec;45(4):235-40. J Neurosurg Sci. 2001. PMID: 11912478 Review.
One unusual case of primary leptomeningeal melanomatosis is presented. The patient, 53-year-old male, was admitted to our observation for 1 month history of psychasthenia and amnesia. ...The present case allows as to identify 2 stages in the evolution of primary dif …
One unusual case of primary leptomeningeal melanomatosis is presented. The patient, 53-year-old male, was admitted to our observat …
Prognostic factors and outcomes in patients with leptomeningeal melanomatosis.
Harstad L, Hess KR, Groves MD. Harstad L, et al. Neuro Oncol. 2008 Dec;10(6):1010-8. doi: 10.1215/15228517-2008-062. Epub 2008 Aug 14. Neuro Oncol. 2008. PMID: 18708343 Free PMC article.
The purpose of this study was to describe a cohort of patients with leptomeningeal melanomatosis (LM) and to determine prognostic factors for outcomes in these patients. ...Multivariate analysis revealed that a history of a primary melanoma lesion originating on the trunk …
The purpose of this study was to describe a cohort of patients with leptomeningeal melanomatosis (LM) and to determine prognostic fac …
Meningeal melanomatosis following discontinuation of dabrafenib: implications for the maintenance of long-term complete remission.
Grätz V, Lüttmann N, Haase O, Langan EA, Kemmling A, Zillikens D, Terheyden P. Grätz V, et al. Melanoma Res. 2017 Oct;27(5):503-506. doi: 10.1097/CMR.0000000000000373. Melanoma Res. 2017. PMID: 28723725
Unfortunately, the response was not maintained and the patient died 9 months later. This observation demonstrates that discontinuation of BRAF inhibition can result in loss of disease control. On the basis of this observation, we suggest that BRAF-targeted therapy s …
Unfortunately, the response was not maintained and the patient died 9 months later. This observation demonstrates that discontinuatio …
Leptomeningeal melanomatosis with multiple cutaneous pigmented nevi: tumor cell proliferation and malignant transformation in an autopsy case.
Oka H, Kameya T, Hata T, Kawano N, Fujii K, Yada K. Oka H, et al. J Neurooncol. 1999 Aug;44(1):41-5. doi: 10.1023/a:1006127619926. J Neurooncol. 1999. PMID: 10582667
A 33-year-old Japanese man was shown to have leptomeningeal melanomatosis with multiple cutaneous pigmented nevi. The autopsy findings showed the presence not only of benign diffuse melanosis of the leptomeninges but also of leptomeningeal melanomatosis in the subar …
A 33-year-old Japanese man was shown to have leptomeningeal melanomatosis with multiple cutaneous pigmented nevi. The autopsy finding …
A case report of a patient with inoperable primary diffuse leptomeningeal melanomatosis treated with whole-brain radiotherapy and pembrolizumab.
Palacka P, Slopovsky J, Makovnik M, Kajo K, Obertova J, Mego M. Palacka P, et al. Medicine (Baltimore). 2022 Jan 21;101(3):e28613. doi: 10.1097/MD.0000000000028613. Medicine (Baltimore). 2022. PMID: 35060532 Free PMC article.
RATIONALE: Primary diffuse leptomeningeal melanomatosis (PDLM) is a rare disease that affects melanocytes in the leptomeninges. ...PATIENT CONCERNS: A patient (23 years old) was diagnosed with PDLM. Histologically, atypical melanocytic cells were also observed. DIAG …
RATIONALE: Primary diffuse leptomeningeal melanomatosis (PDLM) is a rare disease that affects melanocytes in the leptomeninges. ...PA …
Meningeal melanomatosis: a challenge for timely diagnosis.
Berzero G, Diamanti L, Di Stefano AL, Bini P, Franciotta D, Imarisio I, Pedrazzoli P, Magrassi L, Morbini P, Farina LM, Bastianello S, Ceroni M, Marchioni E. Berzero G, et al. Biomed Res Int. 2015;2015:948497. doi: 10.1155/2015/948497. Epub 2015 Jan 14. Biomed Res Int. 2015. PMID: 25648721 Free PMC article.
In the retrospective study herein, we described three cases of meningeal melanomatosis in patients without previous cancer history. The patients were diagnosed with significant delay (17 to 47 weeks from symptom onset) mainly due to the deferral in performing the appropria …
In the retrospective study herein, we described three cases of meningeal melanomatosis in patients without previous cancer history. T …
Extensive metastatic leptomeningeal melanomatosis as the first clinical sign of a cutaneous melanoma: morphological correlations between magnetic resonance imaging and autopsy findings. A case report.
Bussani R, Cova M, Pozzi-Mucelli R, Camilot D, Silvestri F. Bussani R, et al. Hum Pathol. 2003 Jun;34(6):625-8. doi: 10.1016/s0046-8177(03)00120-5. Hum Pathol. 2003. PMID: 12827619
The onset of symptoms, magnetic resonance imaging, and patient death all occurred within a brief time span. To our knowledge, this is the first case of meningeal melanomatosis in a patient not treated with chemotherapeutic drugs in which the radiologic evidence is virtuall …
The onset of symptoms, magnetic resonance imaging, and patient death all occurred within a brief time span. To our knowledge, this is the fi …
Melanoma-associated antigens in tumours of the nervous system: an immunohistochemical study with the monoclonal antibody HMB-45.
Zimmer C, Gottschalk J, Goebel S, Cervos-Navarro J. Zimmer C, et al. Virchows Arch A Pathol Anat Histopathol. 1992;420(2):121-6. doi: 10.1007/BF02358802. Virchows Arch A Pathol Anat Histopathol. 1992. PMID: 1549900
Twenty melanotic tumours (cerebral metastases of malignant melanomas, meningeal melanomatosis, meningeal melanocytomas) and dermal blue cell naevi served as controls. All melanotic tumours stained positive. Furthermore, a positive immunohistochemical reaction was observ …
Twenty melanotic tumours (cerebral metastases of malignant melanomas, meningeal melanomatosis, meningeal melanocytomas) and dermal bl …
12 results