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Treatment of meningeal gliomatosis.
Pradat PF, Hoang-Xuan K, Cornu P, Mokhtari K, Martin-Duverneuil N, Poisson M, Delattre JY. Pradat PF, et al. J Neurooncol. 1999 Sep;44(2):163-8. doi: 10.1023/a:1006399804896. J Neurooncol. 1999. PMID: 10619500
To evaluate whether vigorous treatment is beneficial for patients with meningeal gliomatosis (MG) we reviewed the case records of 20 consecutive patients treated for a symptomatic MG in our center. ...Six patients (30%) achieved a partial response (one low-grade ast …
To evaluate whether vigorous treatment is beneficial for patients with meningeal gliomatosis (MG) we reviewed the case records …
Intrathecal 5-fluoro-2'-deoxyuridine (FdUrd) for the treatment of solid tumor neoplastic meningitis: an in vivo study.
Nakagawa H, Yamada M, Fukushima M, Ikenaka K. Nakagawa H, et al. Cancer Chemother Pharmacol. 1999;43(3):247-56. doi: 10.1007/s002800050891. Cancer Chemother Pharmacol. 1999. PMID: 9923556
FdUrd at doses in the range 5-100 microg/animal was effective against meningeal carcinomatosis using Walker 256 carcinoma cells in rats and MM46 mammary cancer cells in mice and against meningeal gliomatosis using 203 glioma cells in mice. After four intrathecal inj …
FdUrd at doses in the range 5-100 microg/animal was effective against meningeal carcinomatosis using Walker 256 carcinoma cells in rats and …
Adoptive immunotherapy of human meningeal gliomatosis and carcinomatosis with LAK cells and recombinant interleukin-2.
Shimizu K, Okamoto Y, Miyao Y, Yamada M, Ushio Y, Hayakawa T, Ikeda H, Mogami H. Shimizu K, et al. J Neurosurg. 1987 Apr;66(4):519-21. doi: 10.3171/jns.1987.66.4.0519. J Neurosurg. 1987. PMID: 3494108
Adoptive transfer of autologous lymphokine-activated killer (LAK) cells induced in vitro with rIL-2 was used in two patients: one with meningeal gliomatosis and the other with meningeal carcinomatosis. The adoptive transfer of LAK cells was very effective in reducin …
Adoptive transfer of autologous lymphokine-activated killer (LAK) cells induced in vitro with rIL-2 was used in two patients: one with me …
Clinical outcome in aggressively treated meningeal gliomatosis.
Grant R, Naylor B, Junck L, Greenberg HS. Grant R, et al. Neurology. 1992 Jan;42(1):252-4. doi: 10.1212/wnl.42.1.252. Neurology. 1992. PMID: 1310353
We reviewed 11 consecutive patients with an antemortem cytologic diagnosis of meningeal gliomatosis. In three patients, meningeal gliomatosis was diagnosed before surgical resection of the glioma. ...Patients with glioblastoma multiforme did not respon …
We reviewed 11 consecutive patients with an antemortem cytologic diagnosis of meningeal gliomatosis. In three patients, men …
Measurements of CSF biochemical tumor markers in patients with meningeal carcinomatosis and brain tumors.
Nakagawa H, Kubo S, Murasawa A, Nakajima S, Nakajima Y, Izumoto S, Hayakawa T. Nakagawa H, et al. J Neurooncol. 1992 Feb;12(2):111-20. doi: 10.1007/BF00172659. J Neurooncol. 1992. PMID: 1560255
Beta-glucuronidase levels in all cases of meningeal carcinomatosis, meningeal gliomatosis and meningeal lymphoma were higher than 100 micrograms/dl/hr; on the other hand, levels in all cases of benign brain lesions were below 100 micrograms/dl/hr. ...
Beta-glucuronidase levels in all cases of meningeal carcinomatosis, meningeal gliomatosis and meningeal lymphoma were higher t …
Brainstem glioma: clinical manifestations of meningeal gliomatosis.
Packer RJ, Allen J, Nielsen S, Petito C, Deck M, Jereb B. Packer RJ, et al. Ann Neurol. 1983 Aug;14(2):177-82. doi: 10.1002/ana.410140204. Ann Neurol. 1983. PMID: 6625534
Nevertheless, during a two-year period, 5 of 15 such patients treated by us developed symptoms of leptomeningeal metastases. The diagnosis of an anaplastic astrocytoma with meningeal gliomatosis was confirmed postmortem in all 5. In 3 children, meningeal symptoms pr …
Nevertheless, during a two-year period, 5 of 15 such patients treated by us developed symptoms of leptomeningeal metastases. The diagnosis o …
Intrathecal chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea encapsulated into hybrid liposomes for meningeal gliomatosis: an experimental study.
Kitamura I, Kochi M, Matsumoto Y, Ueoka R, Kuratsu J, Ushio Y. Kitamura I, et al. Cancer Res. 1996 Sep 1;56(17):3986-92. Cancer Res. 1996. PMID: 8752168
Wistar rats that were administered lipo-BCNU intracisternally showed no weight loss, neurological symptoms, or histological changes of the brain and spinal cord. A Wistar rat model of meningeal gliomatosis was established by intracisternal inoculation of 0.1 ml cell …
Wistar rats that were administered lipo-BCNU intracisternally showed no weight loss, neurological symptoms, or histological changes of the b …
Survival of patients with high grade glioma treated with intrathecal thiotriethylenephosphoramide for ependymal or leptomeningeal gliomatosis.
Witham TF, Fukui MB, Meltzer CC, Burns R, Kondziolka D, Bozik ME. Witham TF, et al. Cancer. 1999 Oct 1;86(7):1347-53. doi: 10.1002/(sici)1097-0142(19991001)86:7<1347::aid-cncr34>3.0.co;2-m. Cancer. 1999. PMID: 10506724 Clinical Trial.
BACKGROUND: The diagnosis of leptomeningeal dissemination of malignant glioma (meningeal gliomatosis) is associated with poor survival. Intrathecal (IT) chemotherapeutic agents used to achieve tumor control and improve survival include methotrexate, cytosine arabino …
BACKGROUND: The diagnosis of leptomeningeal dissemination of malignant glioma (meningeal gliomatosis) is associated with poor …