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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 2
1968 1
1969 4
1970 2
1971 1
1972 3
1973 3
1974 1
1975 3
1976 2
1977 1
1978 6
1979 5
1980 2
1981 6
1982 7
1983 2
1984 5
1985 6
1986 2
1987 4
1988 5
1989 9
1990 9
1991 6
1992 5
1993 9
1994 16
1995 3
1996 8
1997 6
1998 6
1999 12
2000 14
2001 14
2002 11
2003 9
2004 6
2005 9
2006 15
2007 15
2008 10
2009 15
2010 9
2011 9
2012 12
2013 21
2014 15
2015 15
2016 49
2017 52
2018 35
2019 40
2020 40
2021 38
2022 28
2023 28
2024 10

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Search Results

628 results

Results by year

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Page 1
Zika virus-spread, epidemiology, genome, transmission cycle, clinical manifestation, associated challenges, vaccine and antiviral drug development.
Pielnaa P, Al-Saadawe M, Saro A, Dama MF, Zhou M, Huang Y, Huang J, Xia Z. Pielnaa P, et al. Virology. 2020 Apr;543:34-42. doi: 10.1016/j.virol.2020.01.015. Epub 2020 Feb 2. Virology. 2020. PMID: 32056845 Free article. Review.
This review summarizes the past and present spread of ZIKV outbreak-2007-2019, the genome, transmission cycle, clinical manifestations, vaccine and antiviral drug advancement....
This review summarizes the past and present spread of ZIKV outbreak-2007-2019, the genome, transmission cycle, clinical manifestation …
Intrathecal AAV9/AP4M1 gene therapy for hereditary spastic paraplegia 50 shows safety and efficacy in preclinical studies.
Chen X, Dong T, Hu Y, De Pace R, Mattera R, Eberhardt K, Ziegler M, Pirovolakis T, Sahin M, Bonifacino JS, Ebrahimi-Fakhari D, Gray SJ. Chen X, et al. J Clin Invest. 2023 May 15;133(10):e164575. doi: 10.1172/JCI164575. J Clin Invest. 2023. PMID: 36951961 Free PMC article.
SPG50 is characterized by progressive spastic paraplegia, global developmental delay, and subsequent intellectual disability, secondary microcephaly, and epilepsy. We preformed preclinical studies evaluating an adeno-associated virus (AAV)/AP4M1 gene therapy for SPG50 and …
SPG50 is characterized by progressive spastic paraplegia, global developmental delay, and subsequent intellectual disability, secondary m …
Zika Virus Infection.
Shirley DT, Nataro JP. Shirley DT, et al. Pediatr Clin North Am. 2017 Aug;64(4):937-951. doi: 10.1016/j.pcl.2017.03.012. Pediatr Clin North Am. 2017. PMID: 28734519 Review.
In less than 2 years since entry into the Americas, we have witnessed the emergent spread of Zika virus into large subsets of immunologically naive human populations and then encountered the devastating effects of microcephaly and brain anomalies that can arise from in ute …
In less than 2 years since entry into the Americas, we have witnessed the emergent spread of Zika virus into large subsets of immunologicall …
Zika virus vaccines.
Abbink P, Stephenson KE, Barouch DH. Abbink P, et al. Nat Rev Microbiol. 2018 Oct;16(10):594-600. doi: 10.1038/s41579-018-0039-7. Nat Rev Microbiol. 2018. PMID: 29921914 Free PMC article. Review.
Multiple vaccine candidates have been developed and have shown promising results in both animal models and phase I clinical trials. However, important challenges remain for the clinical development of these vaccines. In this Progress article, we discuss recent precl …
Multiple vaccine candidates have been developed and have shown promising results in both animal models and phase I clinical trials. H …
Cytomegalovirus infection.
Plosa EJ, Esbenshade JC, Fuller MP, Weitkamp JH. Plosa EJ, et al. Pediatr Rev. 2012 Apr;33(4):156-63; quiz 163. doi: 10.1542/pir.33-4-156. Pediatr Rev. 2012. PMID: 22474112 Review.
Other sequelae that may be evident only after the neonatal period can include chorioretinitis, neurodevelopmental delay with mental or motor impairment, and microcephaly. (13) Congenital CMV infection is confirmed by detection of the virus in urine, blood, or saliva within …
Other sequelae that may be evident only after the neonatal period can include chorioretinitis, neurodevelopmental delay with mental or motor …
Fetal cytomegalovirus infection.
Leruez-Ville M, Ville Y. Leruez-Ville M, et al. Best Pract Res Clin Obstet Gynaecol. 2017 Jan;38:97-107. doi: 10.1016/j.bpobgyn.2016.10.005. Epub 2016 Oct 20. Best Pract Res Clin Obstet Gynaecol. 2017. PMID: 27923540 Review.
Natural products as Zika antivirals.
Fong YD, Chu JJH. Fong YD, et al. Med Res Rev. 2022 Sep;42(5):1739-1780. doi: 10.1002/med.21891. Epub 2022 May 20. Med Res Rev. 2022. PMID: 35593443 Free PMC article. Review.
However, severe infections may have neurological implications, such as Guillain-Barre syndrome and fetal microcephaly. To date, there are no existing approved therapeutic drugs or vaccines against ZIKV infections; treatments mainly target the symptoms of infection. ...
However, severe infections may have neurological implications, such as Guillain-Barre syndrome and fetal microcephaly. To date, there …
Molybdenum cofactor deficiency.
Atwal PS, Scaglia F. Atwal PS, et al. Mol Genet Metab. 2016 Jan;117(1):1-4. doi: 10.1016/j.ymgme.2015.11.010. Epub 2015 Nov 25. Mol Genet Metab. 2016. PMID: 26653176 Review.
It is characterized by a neonatal presentation of intractable seizures, feeding difficulties, severe developmental delay, microcephaly with brain atrophy and coarse facial features. MoCD results in deficiency of the molybdenum cofactor dependent enzymes sulfite oxidase, xa …
It is characterized by a neonatal presentation of intractable seizures, feeding difficulties, severe developmental delay, microcephaly …
Zika virus: what, where from and where to?
Basile K, Kok J, Dwyer DE. Basile K, et al. Pathology. 2017 Dec;49(7):698-706. doi: 10.1016/j.pathol.2017.08.002. Epub 2017 Oct 16. Pathology. 2017. PMID: 29050846 Review.
Although Zika virus infection is commonly asymptomatic or mild, emerging evidence suggests a strong link to microcephaly in babies and Guillain-Barre syndrome in adults. This article reviews the epidemiology, geographic distribution, basic virology, transmission, clinic …
Although Zika virus infection is commonly asymptomatic or mild, emerging evidence suggests a strong link to microcephaly in babies an …
Same but different: pleiotropy in centrosome-related microcephaly.
O'Neill RS, Schoborg TA, Rusan NM. O'Neill RS, et al. Mol Biol Cell. 2018 Feb 1;29(3):241-246. doi: 10.1091/mbc.E17-03-0192. Mol Biol Cell. 2018. PMID: 29382806 Free PMC article. Review.
An intimate link between centrosome function and neurogenesis is revealed by the identification of many genes with centrosome-associated functions that are mutated in microcephaly disorders. Consistent with the major role of the centrosome in mitosis, mutations in these ce …
An intimate link between centrosome function and neurogenesis is revealed by the identification of many genes with centrosome-associated fun …
628 results