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Quoted phrase not found in phrase index: "Microsatellite Stable Colon Carcinoma"
Page 1
Alterations in p53, Microsatellite Stability and Lack of MUC5AC Expression as Molecular Features of Colorectal Carcinoma Associated with Inflammatory Bowel Disease.
Gené M, Cuatrecasas M, Amat I, Veiga JA, Fernández Aceñero MJ, Fusté Chimisana V, Tarragona J, Jurado I, Fernández-Victoria R, Martínez Ciarpaglini C, Alenda González C, Zac C, Ortega de la Obra P, Fernández-Figueras MT, Esteller M, Musulen E. Gené M, et al. Int J Mol Sci. 2023 May 12;24(10):8655. doi: 10.3390/ijms24108655. Int J Mol Sci. 2023. PMID: 37240002 Free PMC article.
Recently, gastric metaplasia (GM) has been described as the initial event of the serrated colorectal cancer (CRC) process, resulting from chronic stress on the colon mucosa. The aim of the study is to characterize CAC analyzing p53 alterations and microsatellite ins …
Recently, gastric metaplasia (GM) has been described as the initial event of the serrated colorectal cancer (CRC) process, resulting from ch …
Microsatellite instability in colon cancer: A single center experience from North India.
Arora S, Adhikari N, Rathi AK, Singh K, Sakhuja P. Arora S, et al. J Cancer Res Ther. 2022 Apr-Jun;18(3):656-660. doi: 10.4103/jcrt.jcrt_423_21. J Cancer Res Ther. 2022. PMID: 35900537 Free article.
MSI is one of the major molecular changes that occur in colorectal carcinoma (CRC). Studies have shown that MMR deficient CRC has different clinicopathological characteristics and a better stage adjusted survival when compared to microsatellite stable tumors. …
MSI is one of the major molecular changes that occur in colorectal carcinoma (CRC). Studies have shown that MMR deficient CRC has dif …
The relationship between microsatellite instability in colorectal adenocarcinoma and tumor budding and histopathological parameters.
Topal U, Gülcan P, Yüksel S, Teke Z, Bektaş H, Duman M. Topal U, et al. Eur Rev Med Pharmacol Sci. 2023 Oct;27(20):9793-9800. doi: 10.26355/eurrev_202310_34154. Eur Rev Med Pharmacol Sci. 2023. PMID: 37916344 Free article.
OBJECTIVE: This study aims to investigate the correlation between the presence of microsatellite instability (MSI) and tumor budding, as well as their relationship with histopathological parameters in patients diagnosed with colorectal adenocarcinoma. ...RESULTS: The study …
OBJECTIVE: This study aims to investigate the correlation between the presence of microsatellite instability (MSI) and tumor budding, …
Clinical, Pathology, Genetic, and Molecular Features of Colorectal Tumors in Adolescents and Adults 25 Years or Younger.
de Voer RM, Diets IJ, van der Post RS, Weren RDA, Kamping EJ, de Bitter TJJ, Elze L, Verhoeven RHA, Vink-Börger E, Eijkelenboom A, Mensenkamp A, Nagtegaal ID, Jongmans MCJ, Ligtenberg MJL. de Voer RM, et al. Clin Gastroenterol Hepatol. 2021 Aug;19(8):1642-1651.e8. doi: 10.1016/j.cgh.2020.06.034. Epub 2020 Jun 22. Clin Gastroenterol Hepatol. 2021. PMID: 32585361 Free article.
RESULTS: Mucinous and/or signet ring cell components were observed in 33% of tumor samples. A genetic tumor risk syndrome was confirmed for 39% of cases. ...Compared with colorectal tumors from patients ages 60 years or older in the Cancer Genome Atlas, higher proportions …
RESULTS: Mucinous and/or signet ring cell components were observed in 33% of tumor samples. A genetic tumor risk syndrome was confirm …
Comparative analyses of the prognosis, tumor immune microenvironment, and drug treatment response between left-sided and right-sided colon cancer by integrating scRNA-seq and bulk RNA-seq data.
Cao L, Zhang S, Yao D, Ba Y, Weng Q, Yang J, Zhang H, Ren Y. Cao L, et al. Aging (Albany NY). 2023 Jul 21;15(14):7098-7123. doi: 10.18632/aging.204894. Epub 2023 Jul 21. Aging (Albany NY). 2023. PMID: 37480572 Free PMC article.
RESULTS: We constructed and validated a five-gene prognostic model for LCC patients and a four-gene prognostic model for RCC patients, and both showed excellent performance. The RCC patients with higher risk scores were significantly associated with greater metastasis (P = …
RESULTS: We constructed and validated a five-gene prognostic model for LCC patients and a four-gene prognostic model for RCC patients, and b …
Gastrointestinal mixed adenoneuroendocrine carcinoma (MANEC): An immunohistochemistry study of 13 microsatellite stable cases.
Gurzu S, Fetyko A, Bara T, Banias L, Butiurca VO, Bara T Jr, Tudorache V, Jung I. Gurzu S, et al. Pathol Res Pract. 2019 Dec;215(12):152697. doi: 10.1016/j.prp.2019.152697. Epub 2019 Oct 23. Pathol Res Pract. 2019. PMID: 31704155
BACKGROUND: Mixed adenoneuroendocrine carcinoma (MANEC) is currently included in the category of neuroendocrine carcinomas but the therapeutically management is not yet defined. ...Pure neuroendocrine lymph node metastases were seen in only four of the cases: one fr …
BACKGROUND: Mixed adenoneuroendocrine carcinoma (MANEC) is currently included in the category of neuroendocrine carcinomas but …
Transcriptional profiles underpin microsatellite status and associated features in colon cancer.
Hogan J, DeJulius K, Liu X, Coffey JC, Kalady MF. Hogan J, et al. Gene. 2015 Oct 1;570(1):36-43. doi: 10.1016/j.gene.2015.02.057. Epub 2015 Feb 20. Gene. 2015. PMID: 25704535
INTRODUCTION: While microsatellite instability is associated with prognosis and distinct clinical phenotypes in colon cancer, the basis for this remains incompletely defined. Novel bioinformatic techniques enable a detailed interrogation of the relationship between …
INTRODUCTION: While microsatellite instability is associated with prognosis and distinct clinical phenotypes in colon cancer, …
Presence of Tim3(+) and PD-1(+) CD8(+) T cells identifies microsatellite stable colorectal carcinomas with immune exhaustion and distinct clinicopathological features.
Klapholz M, Drage MG, Srivastava A, Anderson AC. Klapholz M, et al. J Pathol. 2022 Jun;257(2):186-197. doi: 10.1002/path.5877. Epub 2022 Apr 9. J Pathol. 2022. PMID: 35119692
Colorectal carcinoma (CRC) is the second leading cause of cancer mortality worldwide. CRC is stratified into two major groups: microsatellite stable (MSS) and microsatellite instability-high (MSI-H). ...
Colorectal carcinoma (CRC) is the second leading cause of cancer mortality worldwide. CRC is stratified into two major groups: mic …
Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis.
De Smedt L, Lemahieu J, Palmans S, Govaere O, Tousseyn T, Van Cutsem E, Prenen H, Tejpar S, Spaepen M, Matthijs G, Decaestecker C, Moles Lopez X, Demetter P, Salmon I, Sagaert X. De Smedt L, et al. Br J Cancer. 2015 Jul 28;113(3):500-9. doi: 10.1038/bjc.2015.213. Epub 2015 Jun 11. Br J Cancer. 2015. PMID: 26068398 Free PMC article.
BACKGROUND: Microsatellite instability (MSI) accounts for 15% of all colorectal tumours. ...This study aimed to analyse morphological, inflammatory and angiogenic features of MSI vs microsatellite stable (MSS) tumours. METHODS: Twenty-seven MSS and 29 MSI, TN …
BACKGROUND: Microsatellite instability (MSI) accounts for 15% of all colorectal tumours. ...This study aimed to analyse morphological …
Left-sided early-onset vs late-onset colorectal carcinoma: histologic, clinical, and molecular differences.
Pilozzi E, Maresca C, Duranti E, Giustiniani MC, Catalanotto C, Lucarelli M, Cogoni C, Ferri M, Ruco L, Zardo G. Pilozzi E, et al. Am J Clin Pathol. 2015 Mar;143(3):374-84. doi: 10.1309/AJCPNOC55IOLXFUD. Am J Clin Pathol. 2015. PMID: 25696795
OBJECTIVES: Carcinomas of the left colon represent a neoplasm of older patients (late onset), but epidemiologic evidence has been showing an increasing incidence in patients 50 years or younger (early onset). In this study, we investigate pathologic and molecular fe …
OBJECTIVES: Carcinomas of the left colon represent a neoplasm of older patients (late onset), but epidemiologic evidence has b …
84 results