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1977 1
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1989 1
1991 1
1992 1
1995 1
1996 2
1997 1
1998 1
1999 2
2000 1
2002 4
2003 6
2004 1
2006 1
2007 2
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2009 2
2010 2
2012 2
2013 6
2014 3
2015 4
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62 results

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Page 1
Mild hemophilia A.
Franchini M, Favaloro EJ, Lippi G. Franchini M, et al. J Thromb Haemost. 2010 Mar;8(3):421-32. doi: 10.1111/j.1538-7836.2009.03717.x. Epub 2009 Dec 7. J Thromb Haemost. 2010. PMID: 19995408 Free article. Review.
Mild hemophilia A (HA), defined by clinical features and factor VIII coagulant activity (FVIII:C) between 0.05 and 0.40 IU mL(-1), is characteristically distinct from severe HA. ...
Mild hemophilia A (HA), defined by clinical features and factor VIII coagulant activity (FVIII:C) between 0.05 and 0.40 …
Hemophilia A in the third millennium.
Franchini M, Mannucci PM. Franchini M, et al. Blood Rev. 2013 Jul;27(4):179-84. doi: 10.1016/j.blre.2013.06.002. Epub 2013 Jun 28. Blood Rev. 2013. PMID: 23815950 Review.
According to the degree of FVIII deficiency, mild, moderate or severe forms are recognized. Although patients with mild hemophilia A usually bleed excessively only after trauma or surgery, those with severe hemophilia experience frequent episodes of spontaneo …
According to the degree of FVIII deficiency, mild, moderate or severe forms are recognized. Although patients with mild hemophilia …
Emerging Issues in Diagnosis, Biology, and Inhibitor Risk in Mild Hemophilia A.
Castaman G, Eckhardt C, van Velzen A, Linari S, Fijnvandraat K. Castaman G, et al. Semin Thromb Hemost. 2016 Jul;42(5):507-12. doi: 10.1055/s-0036-1571309. Epub 2016 May 5. Semin Thromb Hemost. 2016. PMID: 27148839 Review.
Mild hemophilia A (MHA) is an X-linked bleeding disorder defined by factor VIII (FVIII) levels between 5 and 40 U/dL. ...
Mild hemophilia A (MHA) is an X-linked bleeding disorder defined by factor VIII (FVIII) levels between 5 and 40 U/dL. . …
Diagnosing von Willebrand disease: genetic analysis.
Goodeve A. Goodeve A. Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):678-682. doi: 10.1182/asheducation-2016.1.678. Hematology Am Soc Hematol Educ Program. 2016. PMID: 27913546 Free PMC article. Review.
More recently, next-generation sequencing has become available, with the advantage that several genes can be simultaneously analyzed where necessary, eg, for discrimination of possible type 2N VWD or mild hemophilia A. Additionally, several techniques can now …
More recently, next-generation sequencing has become available, with the advantage that several genes can be simultaneously analyzed where n …
Inhibitors in childhood hemophilia A: genetic and treatment-related risk factors for development and eradication.
DiMichele DM. DiMichele DM. Pediatr Blood Cancer. 2013;60 Suppl 1:S30-3. doi: 10.1002/pbc.24338. Epub 2012 Oct 25. Pediatr Blood Cancer. 2013. PMID: 23109404 Review.
This article will review our current understanding of risk factors and their known impact on inhibitor development in previously untreated or minimally treated children with severe and mild hemophilia A. It will also explore how the most recently elucidated i …
This article will review our current understanding of risk factors and their known impact on inhibitor development in previously untreated o …
A founder effect in hemophilia A patients from Russian Ural region with a new p.(His634Arg) variant in F8 gene.
Salomashkina VV, Pshenichnikova OS, Perina FG, Surin VL. Salomashkina VV, et al. Blood Coagul Fibrinolysis. 2022 Mar 1;33(2):124-129. doi: 10.1097/MBC.0000000000001073. Blood Coagul Fibrinolysis. 2022. PMID: 34393174
We identified a new missense variant p.(His634Arg) in seven apparently unrelated patients with mild hemophilia A from Sverdlovskaya oblast. The haplotype analysis showed that all patients share the same haplotype, absent in the other patients, suggesting a fo …
We identified a new missense variant p.(His634Arg) in seven apparently unrelated patients with mild hemophilia A from S …
Desmopressin therapy in children and adults: pharmacological considerations and clinical implications.
Chin X, Teo SW, Lim ST, Ng YH, Han HC, Yap F. Chin X, et al. Eur J Clin Pharmacol. 2022 Jun;78(6):907-917. doi: 10.1007/s00228-022-03297-z. Epub 2022 Feb 23. Eur J Clin Pharmacol. 2022. PMID: 35199198 Review.
BACKGROUND: Since its discovery 50 years ago, desmopressin's antidiuretic properties have been used for central diabetes insipidus, primary monosymptomatic nocturnal enuresis and adult nocturnal polyuria, while its coagulant effects are useful for mild hemophilia …
BACKGROUND: Since its discovery 50 years ago, desmopressin's antidiuretic properties have been used for central diabetes insipidus, primary …
Desmopressin in mild hemophilia A: indications, limitations, efficacy, and safety.
Lethagen S. Lethagen S. Semin Thromb Hemost. 2003 Feb;29(1):101-6. doi: 10.1055/s-2003-37944. Semin Thromb Hemost. 2003. PMID: 12640572 Review.
Desmopressin is today a widely used hemostatic agent not only in patients with mild hemophilia A or von Willebrand disease (vWD) but also in those with congenital or acquired platelet dysfunction. ...
Desmopressin is today a widely used hemostatic agent not only in patients with mild hemophilia A or von Willebrand dise …
Treatment of inherited coagulation disorders.
Cohen AJ, Kessler CM. Cohen AJ, et al. Am J Med. 1995 Dec;99(6):675-82. doi: 10.1016/s0002-9343(99)80256-3. Am J Med. 1995. PMID: 7503092 Review.
Increased use of pharmacologic agents such as desmopressin acetate for patients with mild hemophilia A or type 1 von Willebrand's disease has allowed physicians to treat patients without the risk of infectious complications from plasma-derived factor concentr …
Increased use of pharmacologic agents such as desmopressin acetate for patients with mild hemophilia A or type 1 von Wi …
62 results