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Page 1
Renal outcome and monoclonal immunoglobulin deposition disease in 289 old patients with blood cell dyscrasias: a single center experience.
Stratta P, Gravellone L, Cena T, Rossi D, Gaidano G, Fenoglio R, Lazzarich E, Quaglia M, Airoldi A, Bozzola C, Monga G, Valente G, Canavese C, Magnani C. Stratta P, et al. Crit Rev Oncol Hematol. 2011 Jul;79(1):31-42. doi: 10.1016/j.critrevonc.2010.05.001. Epub 2010 May 31. Crit Rev Oncol Hematol. 2011. PMID: 20570173 Review.
The kidneys are the most commonly affected organs in MIDD, and renal failure represents an important adverse factor for prognosis. The renal outcome and the role of renal pathology in diagnosing MIDD was evaluated in 289 elderly patients with multiple myeloma (MM, n=115) a …
The kidneys are the most commonly affected organs in MIDD, and renal failure represents an important adverse factor for prognosis. Th …
Randall-type monoclonal immunoglobulin deposition disease: novel insights from a nationwide cohort study.
Joly F, Cohen C, Javaugue V, Bender S, Belmouaz M, Arnulf B, Knebelmann B, Nouvier M, Audard V, Provot F, Gnemmi V, Nochy D, Goujon JM, Jaccard A, Touchard G, Fermand JP, Sirac C, Bridoux F. Joly F, et al. Blood. 2019 Feb 7;133(6):576-587. doi: 10.1182/blood-2018-09-872028. Epub 2018 Dec 21. Blood. 2019. PMID: 30578255 Free article.
FLC response VGPR and absence of severe interstitial fibrosis were independent predictors of renal response. This study highlights an unexpected frequency of extrarenal manifestations in MIDD. Rapid diagnosis and achievement of deep FLC response are key factors of progn …
FLC response VGPR and absence of severe interstitial fibrosis were independent predictors of renal response. This study highlights an …
Nonamyloidotic monoclonal immunoglobulin deposition disease. Light-chain, heavy-chain, and light- and heavy-chain deposition diseases.
Buxbaum J, Gallo G. Buxbaum J, et al. Hematol Oncol Clin North Am. 1999 Dec;13(6):1235-48. doi: 10.1016/s0889-8588(05)70123-4. Hematol Oncol Clin North Am. 1999. PMID: 10626147 Free article. Review.
The authors now believe that the nodular glomerulopathic form of NAMIDD is similar in both course and prognosis to AL amyloidosis occurring in the absence of multiple myeloma (primary amyloidosis). ...The distinction is not trivial, for if the authors are correct, t …
The authors now believe that the nodular glomerulopathic form of NAMIDD is similar in both course and prognosis to AL amyloido …
Monoclonal gammopathy of renal significance: Early diagnosis is key.
Alonso-Titos J, Martínez-Esteban MD, López V, León M, Martin-Reyes G, Ruiz-Esteban P, Hernández D. Alonso-Titos J, et al. Nefrologia (Engl Ed). 2021 Sep-Oct;41(5):502-513. doi: 10.1016/j.nefroe.2021.11.008. Nefrologia (Engl Ed). 2021. PMID: 36165133 Free article.
This term applies to a concept recently introduced owing to the need to differentiate this entity from monoclonal gammopathy of undetermined significance, given the negative prognostic impact of its high morbidity and mortality resulting from both renal and systemic involv …
This term applies to a concept recently introduced owing to the need to differentiate this entity from monoclonal gammopathy of undetermined …
Bortezomib-induced glomerular microangiopathy complicated with monoclonal immunoglobulin deposition disease.
Mizuno S, Kitayama C, Sanada S, Sato T. Mizuno S, et al. CEN Case Rep. 2021 Nov;10(4):537-542. doi: 10.1007/s13730-021-00603-z. Epub 2021 Apr 28. CEN Case Rep. 2021. PMID: 33909224 Free PMC article.
There was no clinical evidence of tumor lysis syndrome or thrombocytopenia throughout the course of his acute kidney injury (AKI). After he became dialysis independent, a renal biopsy was performed to clarify myeloma-related renal involvement and the cause of AKI. ...
There was no clinical evidence of tumor lysis syndrome or thrombocytopenia throughout the course of his acute kidney injury (AKI). Af …
Outcomes of patients with renal monoclonal immunoglobulin deposition disease.
Kourelis TV, Nasr SH, Dispenzieri A, Kumar SK, Gertz MA, Fervenza FC, Buadi FK, Lacy MQ, Erickson SB, Cosio FG, Kapoor P, Lust JA, Hayman SR, Rajkumar V, Zeldenrust SR, Russell SJ, Dingli D, Lin Y, Gonsalves W, Lorenz EC, Zand L, Kyle RA, Leung N. Kourelis TV, et al. Am J Hematol. 2016 Nov;91(11):1123-1128. doi: 10.1002/ajh.24528. Epub 2016 Aug 29. Am J Hematol. 2016. PMID: 27501122 Free article.
Recent reports suggest that deep hematologic responses to chemotherapy are associated with improved renal outcomes in monoclonal immunoglobulin deposition disease (MIDD). Here we describe the long term outcomes and identify prognostic factors after first line treatment of …
Recent reports suggest that deep hematologic responses to chemotherapy are associated with improved renal outcomes in monoclonal immunoglobu …
Renal monoclonal immunoglobulin deposition disease: a report of 64 patients from a single institution.
Nasr SH, Valeri AM, Cornell LD, Fidler ME, Sethi S, D'Agati VD, Leung N. Nasr SH, et al. Clin J Am Soc Nephrol. 2012 Feb;7(2):231-9. doi: 10.2215/CJN.08640811. Epub 2011 Dec 8. Clin J Am Soc Nephrol. 2012. PMID: 22156754
BACKGROUND AND OBJECTIVES: To better define the clinical-pathologic spectrum and prognosis of monoclonal immunoglobulin deposition disease (MIDD), this study reports the largest series. ...Serum free light chain ratio is abnormal in all MIDD patients, whereas only three-qu …
BACKGROUND AND OBJECTIVES: To better define the clinical-pathologic spectrum and prognosis of monoclonal immunoglobulin deposition di …
Hematologic and renal improvement of monoclonal immunoglobulin deposition disease after treatment with bortezomib-based regimens.
Ziogas DC, Kastritis E, Terpos E, Roussou M, Migkou M, Gavriatopoulou M, Spanomichou D, Eleutherakis-Papaiakovou E, Fotiou D, Panagiotidis I, Kafantari E, Psimenou E, Boletis I, Vlahakos DV, Gakiopoulou H, Matsouka C, Dimopoulos MA. Ziogas DC, et al. Leuk Lymphoma. 2017 Aug;58(8):1832-1839. doi: 10.1080/10428194.2016.1267349. Epub 2016 Dec 14. Leuk Lymphoma. 2017. PMID: 27967286
Among patients with CR or VGPR, median eGFR improvement was 7.7 ml/min/1.73 m(2) and none progressed to ESRD, but no significant renal recovery was observed in patients achieving a partial response or less, with 50% progressing to dialysis. Pretreatment eGFR seems to influence re …
Among patients with CR or VGPR, median eGFR improvement was 7.7 ml/min/1.73 m(2) and none progressed to ESRD, but no significant renal recov …
Cyclophosphamide for the Treatment of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition.
Asif S, Mahmood SN, Mukhtar KN. Asif S, et al. Saudi J Kidney Dis Transpl. 2021 Jul-Aug;32(4):1166-1170. doi: 10.4103/1319-2442.338293. Saudi J Kidney Dis Transpl. 2021. PMID: 35229819
PGNMID presents with membranoproliferative glomerulonephritis-type lesions associated with immunoglobulin deposition. This disease entity has a poor prognosis and its optimum treatment is yet to be established. We present the case of an elderly male, a known patient of lig …
PGNMID presents with membranoproliferative glomerulonephritis-type lesions associated with immunoglobulin deposition. This disease entity ha …
Clinicopathological features and prognosis in immunoglobulin light and heavy chain deposition disease.
Masai R, Wakui H, Togashi M, Maki N, Ohtani H, Komatsuda A, Sawada K. Masai R, et al. Clin Nephrol. 2009 Jan;71(1):9-20. doi: 10.5414/cnp71009. Clin Nephrol. 2009. PMID: 19203545
Although it has been considered that LHCDD is a variant of LCDD, information on clinicopathological features and prognosis in LHCDD is presently limited. METHODS: We reviewed 5,443 renal biopsies, and evaluated clinicopathological features and outcomes in patients with LHC …
Although it has been considered that LHCDD is a variant of LCDD, information on clinicopathological features and prognosis in LHCDD i …
26 results