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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
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2002 4
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196 results

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Quoted phrase not found in phrase index: "Monoclonal elevation of IgG"
Page 1
Targeting BAFF and APRIL in systemic lupus erythematosus and other antibody-associated diseases.
Samy E, Wax S, Huard B, Hess H, Schneider P. Samy E, et al. Int Rev Immunol. 2017 Jan 2;36(1):3-19. doi: 10.1080/08830185.2016.1276903. Int Rev Immunol. 2017. PMID: 28215100 Free article. Review.
In addition, BAFF and APRIL are involved in the pathogenesis of a number of human autoimmune diseases, with elevated levels of these cytokines detected in the sera of patients with systemic lupus erythematosus (SLE), IgA nephropathy, Sjogren's syndrome, and rheumatoid arth …
In addition, BAFF and APRIL are involved in the pathogenesis of a number of human autoimmune diseases, with elevated levels of these …
Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumors.
Wingert S, Reusch U, Knackmuss S, Kluge M, Damrat M, Pahl J, Schniegler-Mattox U, Mueller T, Fucek I, Ellwanger K, Tesar M, Haneke T, Koch J, Treder M, Fischer W, Rajkovic E. Wingert S, et al. MAbs. 2021 Jan-Dec;13(1):1950264. doi: 10.1080/19420862.2021.1950264. MAbs. 2021. PMID: 34325617 Free PMC article.
Epidermal growth factor receptor (EGFR)-targeted cancer therapy such as anti-EGFR monoclonal antibodies and tyrosine kinase inhibitors have demonstrated clinical efficacy. ...In vivo, AFM24 was well tolerated up to the highest dose (75 mg/kg) when administered to cynomolgu …
Epidermal growth factor receptor (EGFR)-targeted cancer therapy such as anti-EGFR monoclonal antibodies and tyrosine kinase inhibitor …
Pemphigus: Current and Future Therapeutic Strategies.
Didona D, Maglie R, Eming R, Hertl M. Didona D, et al. Front Immunol. 2019 Jun 25;10:1418. doi: 10.3389/fimmu.2019.01418. eCollection 2019. Front Immunol. 2019. PMID: 31293582 Free PMC article. Review.
The pathogenic relevance of such autoantibodies has been largely demonstrated experimentally. IgG autoantibody binding to Dsg results in loss of epidermal keratinocyte adhesion, a phenomenon referred to as acantholysis. ...Conversely, previous studies from our group have d …
The pathogenic relevance of such autoantibodies has been largely demonstrated experimentally. IgG autoantibody binding to Dsg results …
Management of adverse reactions to biologic agents.
Isabwe GAC, de Las Vecillas Sanchez L, Castells M. Isabwe GAC, et al. Allergy Asthma Proc. 2017 Nov 1;38(6):409-418. doi: 10.2500/aap.2017.38.4085. Allergy Asthma Proc. 2017. PMID: 29046192 Review.
A skin test is a valuable tool in evaluating HSRs to biologics; however, its predictive value depends on the type of reaction and the monoclonal antibody. ...Research is needed to further understand the mechanisms of reactions to monoclonal antibodies and the …
A skin test is a valuable tool in evaluating HSRs to biologics; however, its predictive value depends on the type of reaction and the …
Pathogenesis of IgE-mediated food allergy and implications for future immunotherapeutics.
Ramsey N, Berin MC. Ramsey N, et al. Pediatr Allergy Immunol. 2021 Oct;32(7):1416-1425. doi: 10.1111/pai.13501. Epub 2021 Jun 17. Pediatr Allergy Immunol. 2021. PMID: 33715245 Free PMC article. Review.
Various forms of allergen immunotherapy for food allergy have clearly shown that low specific IgE and elevated specific IgG4 are predictive of sustained treatment effect. Treatments that mimic that immune response, for example, lowering IgE, with monoclonal a …
Various forms of allergen immunotherapy for food allergy have clearly shown that low specific IgE and elevated specific IgG4 are p …
Idiopathic multicentric castleman's disease mimicking immunoglobulin G4-related disease responding well to Bortezomib: a case report.
Peng Q, Wu F, Shi Y, Wang J, Zhai Z, Wang Z. Peng Q, et al. BMC Nephrol. 2023 Oct 2;24(1):290. doi: 10.1186/s12882-023-03335-7. BMC Nephrol. 2023. PMID: 37784011 Free PMC article.
Also, serum and urine immunofixation electrophoresis demonstrated no abnormal monoclonal protein bands. In addition, several laboratory findings excluded chronic liver disease, chronic infections caused by bacteria or viruses. Later, we found elevated serum IgG4 lev …
Also, serum and urine immunofixation electrophoresis demonstrated no abnormal monoclonal protein bands. In addition, several laborato …
Attack adjudication in neuromyelitis optica spectrum disorder: Substantiation of criteria by magnetic resonance imaging and biomarkers in N-MOmentum.
Weinshenker BG, Wingerchuk DM, Green AJ, Bennett JL, Kim HJ, Pittock SJ, Fujihara K, Paul F, Cutter G, Marignier R, Aktas O, Hartung HP, She D, Smith M, Rees W, Patterson K, Cimbora D, Katz E, Cree BA. Weinshenker BG, et al. Mult Scler. 2023 Jul;29(8):945-955. doi: 10.1177/13524585231172145. Epub 2023 Jun 6. Mult Scler. 2023. PMID: 37282545 Free PMC article. Clinical Trial.
METHODS: Adults (n = 230) with NMOSD and Expanded Disability Status Scale score 8 were randomized (3:1) to inebilizumab 300 mg or placebo. ...CONCLUSION: AC adjudication of NMOSD attacks according to predefined criteria appears robust. MRI lesion correlates and sGFAP el …
METHODS: Adults (n = 230) with NMOSD and Expanded Disability Status Scale score 8 were randomized (3:1) to inebilizumab 300 mg or pla …
Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation.
Cheng D, Luo Z, Fu X, Stephenson S, Di Germanio C, Norris PJ, Fuchs D, Ndhlovu LC, Li QZ, Zetterberg H, Gisslen M, Price RW, Peng S, Jiang W. Cheng D, et al. Microbiol Spectr. 2022 Feb 23;10(1):e0197521. doi: 10.1128/spectrum.01975-21. Epub 2022 Jan 5. Microbiol Spectr. 2022. PMID: 34985329 Free PMC article.
We found that 37% of the PWH exhibited elevated CSF anti-CD4 IgG levels, but few or none of the PWH were observed with elevated CSF anti-CD4 IgM, anti-CD8 IgG, or anti-double-strand DNA IgG. ...This study demonstrates for the first time t …
We found that 37% of the PWH exhibited elevated CSF anti-CD4 IgG levels, but few or none of the PWH were observed with …
Afucosylation of HLA-specific IgG1 as a potential predictor of antibody pathogenicity in kidney transplantation.
Bharadwaj P, Shrestha S, Pongracz T, Concetta C, Sharma S, Le Moine A, de Haan N, Murakami N, Riella LV, Holovska V, Wuhrer M, Marchant A, Ackerman ME. Bharadwaj P, et al. Cell Rep Med. 2022 Nov 15;3(11):100818. doi: 10.1016/j.xcrm.2022.100818. Cell Rep Med. 2022. PMID: 36384101 Free PMC article.
Levels of afucosylated anti-A2 antibodies are elevated in seropositive patients, especially those with AMR, suggesting potential cytotoxicity via FcgammaRIII-mediated mechanisms. Afucosylation of both glycoengineered monoclonal and naturally glycovariant polyclonal …
Levels of afucosylated anti-A2 antibodies are elevated in seropositive patients, especially those with AMR, suggesting potential cyto …
Lymphoplasmacytic lymphoma with IgG-kappa paraproteinemia presenting as a hepatic bulky mass.
Higuchi M, Senoo T, Morita C, Furugo I, Hamada T, Ohshima K. Higuchi M, et al. J Clin Exp Hematop. 2022;62(4):273-278. doi: 10.3960/jslrt.22037. J Clin Exp Hematop. 2022. PMID: 36575005 Free PMC article.
Laboratory findings showed a normal white blood cell count of 4.110(9)/L with 4% plasmacytoid lymphocytes; normocytic anemia, Hb 9.4 g/dL; high soluble IL-2 receptor level, 2,290 U/mL; and elevated IgG, 10,306 mg/dL. Furthermore, IgG-kappa monoclonal p …
Laboratory findings showed a normal white blood cell count of 4.110(9)/L with 4% plasmacytoid lymphocytes; normocytic anemia, Hb 9.4 g/dL; h …
196 results