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Quoted phrase not found in phrase index: "Multiple pancreatic beta-cell adenomas"
Page 1
Oncogenic co-operation in beta-cell tumorigenesis.
Pelengaris S, Khan M. Pelengaris S, et al. Endocr Relat Cancer. 2001 Dec;8(4):307-14. doi: 10.1677/erc.0.0080307. Endocr Relat Cancer. 2001. PMID: 11733227 Review.
Pancreatic islet neoplasms are rare endocrine tumours. The most common type is of beta-cell origin and is known as insulinoma, which can be either benign or malignant. ...Although Myc activation initially promotes both proliferation and apoptosis in pancre …
Pancreatic islet neoplasms are rare endocrine tumours. The most common type is of beta-cell origin and is known as insu …
Difference in the early clinical course between children with type 1 diabetes having a single antibody and those having multiple antibodies against pancreatic beta-cells.
Terada H, Urakami T, Nagano N, Mine Y, Kuwabara R, Aoki M, Suzuki J, Morioka I. Terada H, et al. Endocr J. 2023 Apr 28;70(4):385-391. doi: 10.1507/endocrj.EJ22-0432. Epub 2023 Jan 24. Endocr J. 2023. PMID: 36696992 Free article.
Islet-cell associated antibodies are predictive and diagnostic markers for type 1 diabetes. ...We compared the patients' clinical characteristics, pancreatic beta-cell function, and glycemic control during the 5 years after diagnosis. ...
Islet-cell associated antibodies are predictive and diagnostic markers for type 1 diabetes. ...We compared the patients' clini …
Relationship between genotype and phenotype in monogenic diseases: relevance to polygenic diseases.
Summers KM. Summers KM. Hum Mutat. 1996;7(4):283-93. doi: 10.1002/(SICI)1098-1004(1996)7:4<283::AID-HUMU1>3.0.CO;2-A. Hum Mutat. 1996. PMID: 8723677 Review.
Since the early descriptions of sickle cell anemia, it has been clear that genotype at a single locus rarely completely predicts phenotype. ...There may be genetically determined variation in flux through the minor metabolic pathways for phenylalanine, influencing l …
Since the early descriptions of sickle cell anemia, it has been clear that genotype at a single locus rarely completely predicts …
Synchronous Nesidioblastosis, Endocrine Microadenoma, and Intraductal Papillary Mucinous Neoplasia in a Man Presenting With Hyperinsulinemic Hypoglycemia.
De Sousa SM, Haghighi KS, Qiu MR, Greenfield JR, Chen DL. De Sousa SM, et al. Pancreas. 2016 Jan;45(1):154-9. doi: 10.1097/MPA.0000000000000430. Pancreas. 2016. PMID: 26658039 Review.
The patient was a 33-year-old man who presented with symptomatic hyperinsulinemic hypoglycemia and no risk factors for pancreatic disease. Abdominal imaging showed an isolated 12 mm pancreatic lesion, whilst selective arterial calcium stimulation testing demonstrate …
The patient was a 33-year-old man who presented with symptomatic hyperinsulinemic hypoglycemia and no risk factors for pancreatic dis …
The embryonic transcription factor Hlxb9 is a menin interacting partner that controls pancreatic beta-cell proliferation and the expression of insulin regulators.
Shi K, Parekh VI, Roy S, Desai SS, Agarwal SK. Shi K, et al. Endocr Relat Cancer. 2013 Feb 18;20(1):111-22. doi: 10.1530/ERC-12-0077. Print 2013 Feb. Endocr Relat Cancer. 2013. PMID: 23419452 Free PMC article.
Also, 30-40% of sporadic pancreatic endocrine tumors show somatic MEN1 gene inactivation. Although menin is expressed in all cell types of the pancreas, mouse models with loss of menin in either pancreatic alpha-cells, or beta-cells, or t …
Also, 30-40% of sporadic pancreatic endocrine tumors show somatic MEN1 gene inactivation. Although menin is expressed in all cell …
Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma.
Hamze Z, Vercherat C, Bernigaud-Lacheretz A, Bazzi W, Bonnavion R, Lu J, Calender A, Pouponnot C, Bertolino P, Roche C, Stein R, Scoazec JY, Zhang CX, Cordier-Bussat M. Hamze Z, et al. Endocr Relat Cancer. 2013 Oct 24;20(6):833-48. doi: 10.1530/ERC-13-0164. Print 2013 Dec. Endocr Relat Cancer. 2013. PMID: 24157940 Free PMC article.
We chose the insulinoma model, a paradigmatic example of well-differentiated pancreatic NETs, to study whether MENIN interferes with the expression of v-MAF musculoaponeurotic fibrosarcoma oncogene homologue A (MAFA), a master glucose-dependent transcription factor in diff …
We chose the insulinoma model, a paradigmatic example of well-differentiated pancreatic NETs, to study whether MENIN interferes with …
New Regions With Molecular Alterations in a Rare Case of Insulinomatosis: Case Report With Literature Review.
Anoshkin K, Vasilyev I, Karandasheva K, Shugay M, Kudryavtseva V, Egorov A, Gurevich L, Mironova A, Serikov A, Kutsev S, Strelnikov V. Anoshkin K, et al. Front Endocrinol (Lausanne). 2021 Oct 19;12:760154. doi: 10.3389/fendo.2021.760154. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34737724 Free PMC article. Review.
One of the main characteristics of insulinomatosis is the presence of insulin-expressing monohormonal endocrine cell clusters that are exclusively composed of proliferating insulin-positive cells, are less than 1 mm in size, and show solid islet-like structure. ...C …
One of the main characteristics of insulinomatosis is the presence of insulin-expressing monohormonal endocrine cell clusters that ar …
Limited value of 18F-F-DOPA PET to localize pancreatic insulin-secreting tumors in adults with hyperinsulinemic hypoglycemia.
Tessonnier L, Sebag F, Ghander C, De Micco C, Reynaud R, Palazzo FF, Conte-Devolx B, Henry JF, Mundler O, Taïeb D. Tessonnier L, et al. J Clin Endocrinol Metab. 2010 Jan;95(1):303-7. doi: 10.1210/jc.2009-1357. Epub 2009 Nov 13. J Clin Endocrinol Metab. 2010. PMID: 19915018
RESULTS: Using visual analysis, 18F-FDOPA-PET proved positive in only one case (a multiple endocrine neoplasia type 1 related insulinoma). In diffuse beta-cell hyperplasia, the pancreatic uptake was similar to controls. ...This drawback is potentially …
RESULTS: Using visual analysis, 18F-FDOPA-PET proved positive in only one case (a multiple endocrine neoplasia type 1 related insulin …
Familial adenomatous polyposis associated with multiple endocrine neoplasia type 1-related tumors and thyroid carcinoma: a case report with clinicopathologic and molecular analyses.
Sakai Y, Koizumi K, Sugitani I, Nakagawa K, Arai M, Utsunomiya J, Muto T, Fujita R, Kato Y. Sakai Y, et al. Am J Surg Pathol. 2002 Jan;26(1):103-10. doi: 10.1097/00000478-200201000-00014. Am J Surg Pathol. 2002. PMID: 11756777
We describe a sporadic case with familial adenomatous polyposis, multiple endocrine neoplasia type 1 (MEN1)-related tumors (an endocrine cell tumor of the pancreas and bilateral parathyroid tumors), and a papillary thyroid carcinoma. ...A germline mutation was found …
We describe a sporadic case with familial adenomatous polyposis, multiple endocrine neoplasia type 1 (MEN1)-related tumors (an endocr …
Glucosamine treatment-mediated O-GlcNAc modification of paxillin depends on adhesion state of rat insulinoma INS-1 cells.
Kwak TK, Kim H, Jung O, Lee SA, Kang M, Kim HJ, Park JM, Kim SH, Lee JW. Kwak TK, et al. J Biol Chem. 2010 Nov 12;285(46):36021-31. doi: 10.1074/jbc.M110.129601. Epub 2010 Sep 9. J Biol Chem. 2010. PMID: 20829364 Free PMC article.
Integrin-mediated adhesion signaling inhibited the GlcN treatment-enhanced O-GlcNAc modification of paxillin. Adherent INS-1 cells treated with GlcN showed restricted protrusions, whereas untreated cells showed active protrusions for multiple-elongated morpho …
Integrin-mediated adhesion signaling inhibited the GlcN treatment-enhanced O-GlcNAc modification of paxillin. Adherent INS-1 cells tr …