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Quoted phrase not found in phrase index: "Multiple pancreatic beta-cell adenomas"
Page 1
Prognostic transcriptome classes of duodenopancreatic neuroendocrine tumors.
Diedisheim M, Dermine S, Jouinot A, Septier A, Gaujoux S, Dousset B, Cadiot G, Larger E, Bertherat J, Scharfmann R, Terris B, Coriat R, Assié G. Diedisheim M, et al. Endocr Relat Cancer. 2021 Jun 21;28(8):563-571. doi: 10.1530/ERC-21-0051. Endocr Relat Cancer. 2021. PMID: 34061769

Three distinct molecular groups were identified, associated with distinct outcomes (log-rank P < 0.01): (i) better-outcome DPNETs with pancreatic beta-cell signature. This group was mainly composed of well-differentiated, grade 1 insulinomas; (ii) poor-out

…

Three distinct molecular groups were identified, associated with distinct outcomes (log-rank P < 0.01): (i) better-outcome DPNETs with

…
Difference in the early clinical course between children with type 1 diabetes having a single antibody and those having multiple antibodies against pancreatic beta-cells.
Terada H, Urakami T, Nagano N, Mine Y, Kuwabara R, Aoki M, Suzuki J, Morioka I. Terada H, et al. Endocr J. 2023 Apr 28;70(4):385-391. doi: 10.1507/endocrj.EJ22-0432. Epub 2023 Jan 24. Endocr J. 2023. PMID: 36696992 Free article.
Islet-cell associated antibodies are predictive and diagnostic markers for type 1 diabetes. We studied the differences in the early clinical course of children with type 1 diabetes with a single antibody and those with multiple antibodies against pa …
Islet-cell associated antibodies are predictive and diagnostic markers for type 1 diabetes. We studied the differences in the …
The embryonic transcription factor Hlxb9 is a menin interacting partner that controls pancreatic beta-cell proliferation and the expression of insulin regulators.
Shi K, Parekh VI, Roy S, Desai SS, Agarwal SK. Shi K, et al. Endocr Relat Cancer. 2013 Feb 18;20(1):111-22. doi: 10.1530/ERC-12-0077. Print 2013 Feb. Endocr Relat Cancer. 2013. PMID: 23419452 Free PMC article.
Also, 30-40% of sporadic pancreatic endocrine tumors show somatic MEN1 gene inactivation. Although menin is expressed in all cell types of the pancreas, mouse models with loss of menin in either pancreatic alpha-cells, or beta-cells, or t …
Also, 30-40% of sporadic pancreatic endocrine tumors show somatic MEN1 gene inactivation. Although menin is expressed in all cell …
Relationship between genotype and phenotype in monogenic diseases: relevance to polygenic diseases.
Summers KM. Summers KM. Hum Mutat. 1996;7(4):283-93. doi: 10.1002/(SICI)1098-1004(1996)7:4<283::AID-HUMU1>3.0.CO;2-A. Hum Mutat. 1996. PMID: 8723677 Review.
Since the early descriptions of sickle cell anemia, it has been clear that genotype at a single locus rarely completely predicts phenotype. ...There may be genetically determined variation in flux through the minor metabolic pathways for phenylalanine, influencing l …
Since the early descriptions of sickle cell anemia, it has been clear that genotype at a single locus rarely completely predicts …
Synchronous Nesidioblastosis, Endocrine Microadenoma, and Intraductal Papillary Mucinous Neoplasia in a Man Presenting With Hyperinsulinemic Hypoglycemia.
De Sousa SM, Haghighi KS, Qiu MR, Greenfield JR, Chen DL. De Sousa SM, et al. Pancreas. 2016 Jan;45(1):154-9. doi: 10.1097/MPA.0000000000000430. Pancreas. 2016. PMID: 26658039 Review.
The patient was a 33-year-old man who presented with symptomatic hyperinsulinemic hypoglycemia and no risk factors for pancreatic disease. Abdominal imaging showed an isolated 12 mm pancreatic lesion, whilst selective arterial calcium stimulation testing demonstrate …
The patient was a 33-year-old man who presented with symptomatic hyperinsulinemic hypoglycemia and no risk factors for pancreatic dis …
Limited value of 18F-F-DOPA PET to localize pancreatic insulin-secreting tumors in adults with hyperinsulinemic hypoglycemia.
Tessonnier L, Sebag F, Ghander C, De Micco C, Reynaud R, Palazzo FF, Conte-Devolx B, Henry JF, Mundler O, Taïeb D. Tessonnier L, et al. J Clin Endocrinol Metab. 2010 Jan;95(1):303-7. doi: 10.1210/jc.2009-1357. Epub 2009 Nov 13. J Clin Endocrinol Metab. 2010. PMID: 19915018
RESULTS: Using visual analysis, 18F-FDOPA-PET proved positive in only one case (a multiple endocrine neoplasia type 1 related insulinoma). In diffuse beta-cell hyperplasia, the pancreatic uptake was similar to controls. ...This drawback is potentially …
RESULTS: Using visual analysis, 18F-FDOPA-PET proved positive in only one case (a multiple endocrine neoplasia type 1 related insulin …
Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery.
Service GJ, Thompson GB, Service FJ, Andrews JC, Collazo-Clavell ML, Lloyd RV. Service GJ, et al. N Engl J Med. 2005 Jul 21;353(3):249-54. doi: 10.1056/NEJMoa043690. N Engl J Med. 2005. PMID: 16034010 Free article.
Nesidioblastosis was identified in resected specimens from each patient, and multiple insulinomas were identified in one. Hypoglycemic symptoms diminished postoperatively. We speculate that hyperfunction of pancreatic islets did not lead to obesity but that beta …
Nesidioblastosis was identified in resected specimens from each patient, and multiple insulinomas were identified in one. Hypoglycemi …