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Page 1
Neuroimaging Applications in Chronic Ataxias.
Mascalchi M, Vella A. Mascalchi M, et al. Int Rev Neurobiol. 2018;143:109-162. doi: 10.1016/bs.irn.2018.09.011. Epub 2018 Oct 29. Int Rev Neurobiol. 2018. PMID: 30473193 Review.
MRI has a predominant diagnostic role in the single patient, based on the visual detection of three patterns of atrophy, namely, spinal atrophy, cortical cerebellar atrophy and olivopontocerebellar atrophy, which correlate with the aetiologies of inherited or sporadic ataxia. In …
MRI has a predominant diagnostic role in the single patient, based on the visual detection of three patterns of atrophy, namely, spinal atro …
Unravelling the etiology of sporadic late-onset cerebellar ataxia in a cohort of 205 patients: a prospective study.
Bogdan T, Wirth T, Iosif A, Schalk A, Montaut S, Bonnard C, Carre G, Lagha-Boukbiza O, Reschwein C, Albugues E, Demuth S, Landsberger H, Einsiedler M, Parratte T, Nguyen A, Lamy F, Durand H, Fahrer P, Voulleminot P, Bigaut K, Chanson JB, Nicolas G, Chelly J, Cazeneuve C, Koenig M, Bund C, Namer IJ, Kremer S, Calmels N, Tranchant C, Anheim M. Bogdan T, et al. J Neurol. 2022 Dec;269(12):6354-6365. doi: 10.1007/s00415-022-11253-1. Epub 2022 Jul 23. J Neurol. 2022. PMID: 35869996
RESULTS: We established a diagnosis in 135 (66%) patients and reported 26 different causes for SLOCA, the most frequent being multiple system atrophy cerebellar type (MSA-C) (41%). Fifty-one patients (25%) had various causes of SLOCA including i …
RESULTS: We established a diagnosis in 135 (66%) patients and reported 26 different causes for SLOCA, the most frequent being multiple
Swallowing Outcomes Following Voice Therapy in Multiple System Atrophy with Dysphagia: Comparison of Treatment Efficacy with Parkinson's Disease.
Park A, Jang SJ, Kim NE, Kim TH, Sohn YH, Kim H, Cho SR. Park A, et al. Dysphagia. 2022 Feb;37(1):198-206. doi: 10.1007/s00455-021-10265-9. Epub 2021 Mar 5. Dysphagia. 2022. PMID: 33666739 Free PMC article.
Lee Silverman Voice Treatment (LSVT) is proven as an effective treatment for speech and swallowing function in idiopathic Parkinson's disease (IPD). The effect of LSVT on swallowing function in multiple system atrophy-cerebellar type (MSA-C) is …
Lee Silverman Voice Treatment (LSVT) is proven as an effective treatment for speech and swallowing function in idiopathic Parkinson's diseas …
Differences between spinocerebellar ataxias and multiple system atrophy-cerebellar type on proton magnetic resonance spectroscopy.
Lirng JF, Wang PS, Chen HC, Soong BW, Guo WY, Wu HM, Chang CY. Lirng JF, et al. PLoS One. 2012;7(10):e47925. doi: 10.1371/journal.pone.0047925. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23118909 Free PMC article.
The cerebellar NAA/Cho in MSA-C was lower than SCA3 (p<0.0005). In the early stages of diseases (SARA score<10), significant lower NAA/Cr and NAA/Cho in SCA2, SCA3, SCA6 or MSA-C were observed comparing with healthy controls (p<0.017). ...Rapid neuronal deg …
The cerebellar NAA/Cho in MSA-C was lower than SCA3 (p<0.0005). In the early stages of diseases (SARA score<10), significant lo …
Amelioration of motor and nonmotor symptoms in cortical cerebellar atrophy and multiple system atrophy-cerebellar type by inpatient rehabilitation: a retrospective study.
Sonoda Y, Yamanaka Y, Sawano S, Komada R, Kugo M, Kitamura A, Ogawa N, Yamakawa I, Kim H, Sanada M, Imai S, Urushitani M. Sonoda Y, et al. Int J Rehabil Res. 2021 Jun 1;44(2):104-109. doi: 10.1097/MRR.0000000000000455. Int J Rehabil Res. 2021. PMID: 33481455 Clinical Trial.
Sporadic spinocerebellar degenerative diseases such as multiple system atrophy (cerebellar type) and cortical cerebellar atrophy typically present with cerebellar ataxia. ...In patients with multiple system atrophy, rehabilitation significantly …
Sporadic spinocerebellar degenerative diseases such as multiple system atrophy (cerebellar type) and cort …
Early decrease in intermediate monocytes in peripheral blood is characteristic of multiple system atrophy-cerebellar type.
Matsuse D, Yamasaki R, Maimaitijiang G, Yamaguchi H, Masaki K, Isobe N, Matsushita T, Kira JI. Matsuse D, et al. J Neuroimmunol. 2020 Dec 15;349:577395. doi: 10.1016/j.jneuroim.2020.577395. Epub 2020 Sep 20. J Neuroimmunol. 2020. PMID: 32977251
To identify biomarkers for multiple system atrophy-cerebellar type (MSA-C), we used flow cytometry to measure surface marker expression of peripheral blood monocytes from patients with MSA-C or hereditary spinocerebellar degeneration (hSCD) and …
To identify biomarkers for multiple system atrophy-cerebellar type (MSA-C), we used flow cytometry to mea …
Clinical and genetic characteristics of sporadic adult-onset degenerative ataxia.
Giordano I, Harmuth F, Jacobi H, Paap B, Vielhaber S, Machts J, Schöls L, Synofzik M, Sturm M, Tallaksen C, Wedding IM, Boesch S, Eigentler A, van de Warrenburg B, van Gaalen J, Kamm C, Dudesek A, Kang JS, Timmann D, Silvestri G, Masciullo M, Klopstock T, Neuhofer C, Ganos C, Filla A, Bauer P, Tezenas du Montcel S, Klockgether T. Giordano I, et al. Neurology. 2017 Sep 5;89(10):1043-1049. doi: 10.1212/WNL.0000000000004311. Epub 2017 Aug 9. Neurology. 2017. PMID: 28794257 Clinical Trial.
Among them, 83 met diagnostic criteria of clinically probable multiple system atrophy cerebellar type (MSA-C) at baseline and another 12 during follow-up. ...Compared with MSA-C, SAOA/non-MSA patients had lower SARA scores (13.6 6.0 vs 16 …
Among them, 83 met diagnostic criteria of clinically probable multiple system atrophy cerebellar type (MS …
Three Hertz postural leg tremor impairs posture maintenance in multiple system atrophy-cerebellar type.
Wang Y, Liu C, Ma G, Lv X, Li X. Wang Y, et al. Neurol Sci. 2024 Feb;45(2):601-612. doi: 10.1007/s10072-023-07036-9. Epub 2023 Sep 1. Neurol Sci. 2024. PMID: 37656288
Medium and high-frequency values were strongly and positively inter-correlated in normal stances, but this was not observed among the spinocerebellar ataxia or multiple system atrophy patients. ...Medium frequency proportions were also inversely correlated with tremors amo …
Medium and high-frequency values were strongly and positively inter-correlated in normal stances, but this was not observed among the …
3-Hz postural tremor in multiple system atrophy cerebellar type (MSA-C)-a static posturography study.
Li X, Wang Y, Wang Z, Xu Y, Zheng W. Li X, et al. Neurol Sci. 2018 Jan;39(1):71-77. doi: 10.1007/s10072-017-3130-3. Epub 2017 Oct 12. Neurol Sci. 2018. PMID: 29027029

Compared with HC, SOT scores were significantly lower in MSA groups (P < 0.01). Compared with MSA-P, the vestibular scores were further reduced in MSA-C patients (P < 0.05). Falls were more frequent in MSA groups, especially in SOT4 task (foam surface with eye

Compared with HC, SOT scores were significantly lower in MSA groups (P < 0.01). Compared with MSA-P, the vestibular scores

Significance of combined use of MRI and perfusion SPECT for evaluation of multiple system atrophy, cerebellar type.
Miyoshi F, Kanasaki Y, Shinohara Y, Fujii S, Kaminou T, Tanabe Y, Ogawa T. Miyoshi F, et al. Acta Radiol. 2016 Jun;57(6):742-9. doi: 10.1177/0284185115598810. Epub 2015 Aug 7. Acta Radiol. 2016. PMID: 26253930
BACKGROUND: Multiple system atrophy, cerebellar type (MSA-C) sometimes shows asymmetrical findings on magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT). ...Including the latest and past images, asymmetrical …
BACKGROUND: Multiple system atrophy, cerebellar type (MSA-C) sometimes shows asymmetrical findings on mag …
19 results