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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1963 1
1964 2
1965 4
1966 7
1967 7
1968 9
1969 5
1970 9
1971 10
1972 11
1973 11
1974 11
1975 19
1976 14
1977 16
1978 19
1979 15
1980 19
1981 18
1982 23
1983 22
1984 22
1985 30
1986 18
1987 25
1988 29
1989 32
1990 37
1991 59
1992 40
1993 69
1994 69
1995 54
1996 66
1997 50
1998 60
1999 54
2000 70
2001 61
2002 96
2003 93
2004 89
2005 106
2006 112
2007 100
2008 120
2009 129
2010 139
2011 126
2012 133
2013 163
2014 180
2015 131
2016 146
2017 171
2018 197
2019 205
2020 189
2021 199
2022 189
2023 151
2024 64

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Search Results

3,951 results

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Page 1
Coenzyme Q10.
Raizner AE. Raizner AE. Methodist Debakey Cardiovasc J. 2019 Jul-Sep;15(3):185-191. doi: 10.14797/mdcj-15-3-185. Methodist Debakey Cardiovasc J. 2019. PMID: 31687097 Free PMC article. Review.
In CHF, there is a lack of large-scale randomized clinical trial data regarding the use of statins in patients receiving contemporary treatment. However, one relatively recent randomized clinical trial, Q-SYMBIO, suggests an adjunctive ro …
In CHF, there is a lack of large-scale randomized clinical trial data regarding the use of statins in patients receivin …
Cardioembolic Stroke.
Kamel H, Healey JS. Kamel H, et al. Circ Res. 2017 Feb 3;120(3):514-526. doi: 10.1161/CIRCRESAHA.116.308407. Circ Res. 2017. PMID: 28154101 Free PMC article. Review.
First, although one-third of strokes are of unclear cause, it is increasingly accepted that many of these cryptogenic strokes arise from a distant embolism rather than in situ cerebrovascular disease, leading to the recent formulation of embolic stroke of undetermined source as a …
First, although one-third of strokes are of unclear cause, it is increasingly accepted that many of these cryptogenic strokes arise from a d …
Interpretation of the evidence for the efficacy and safety of statin therapy.
Collins R, Reith C, Emberson J, Armitage J, Baigent C, Blackwell L, Blumenthal R, Danesh J, Smith GD, DeMets D, Evans S, Law M, MacMahon S, Martin S, Neal B, Poulter N, Preiss D, Ridker P, Roberts I, Rodgers A, Sandercock P, Schulz K, Sever P, Simes J, Smeeth L, Wald N, Yusuf S, Peto R. Collins R, et al. Lancet. 2016 Nov 19;388(10059):2532-2561. doi: 10.1016/S0140-6736(16)31357-5. Epub 2016 Sep 8. Lancet. 2016. PMID: 27616593 Free article. Review.
This Review is intended to help clinicians, patients, and the public make informed decisions about statin therapy for the prevention of heart attacks and strokes. It explains how the evidence that is available from randomised controlled trials yields reliable information a …
This Review is intended to help clinicians, patients, and the public make informed decisions about statin therapy for the prevention of hear …
Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
Qu H, Guo M, Chai H, Wang WT, Gao ZY, Shi DZ. Qu H, et al. J Am Heart Assoc. 2018 Oct 2;7(19):e009835. doi: 10.1161/JAHA.118.009835. J Am Heart Assoc. 2018. PMID: 30371340 Free PMC article. Review.
Background Previous studies have demonstrated a possible association between the induction of coenzyme Q10 (CoQ10) after statin treatment and statin-induced myopathy. However, whether CoQ10 supplementation ameliorates statin-induced myopathy remains unclear. Methods …
Background Previous studies have demonstrated a possible association between the induction of coenzyme Q10 (CoQ10) after statin treatment an …
Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions.
Weber T. Weber T. Front Immunol. 2021 Mar 17;12:658399. doi: 10.3389/fimmu.2021.658399. eCollection 2021. Front Immunol. 2021. PMID: 33815421 Free PMC article. Review.
Adeno-associated virus (AAV) vector-based gene therapy is currently the only in vivo gene therapy approved in the US and Europe. The recent tragic death of three children in a clinical trial to treat X-Linked Myotubular Myopathy by delivering myotubularin wit …
Adeno-associated virus (AAV) vector-based gene therapy is currently the only in vivo gene therapy approved in the US and Europe. The recent …
Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials.
Cholesterol Treatment Trialists' Collaboration. Cholesterol Treatment Trialists' Collaboration. Lancet. 2022 Sep 10;400(10355):832-845. doi: 10.1016/S0140-6736(22)01545-8. Epub 2022 Aug 29. Lancet. 2022. PMID: 36049498 Free PMC article.
We aimed to address these through an individual participant data meta-analysis of all recorded adverse muscle events in large, long-term, randomised, double-blind trials of statin therapy. METHODS: Randomised trials of statin therapy were eligible if they aimed to r …
We aimed to address these through an individual participant data meta-analysis of all recorded adverse muscle events in large, long-term, …
Statin-related myotoxicity.
Fernandes V, Santos MJ, Pérez A. Fernandes V, et al. Endocrinol Nutr. 2016 May;63(5):239-49. doi: 10.1016/j.endonu.2016.01.001. Epub 2016 Mar 19. Endocrinol Nutr. 2016. PMID: 27005745 Review. English, Spanish.
Because of the high proportion of patients on statin treatment and the frequency of statin-related myotoxicity, this is a subject of concern in clinical practice. However, statin-related myotoxicity is probably underestimated because there is not a gold standard definition …
Because of the high proportion of patients on statin treatment and the frequency of statin-related myotoxicity, this is a subject of concern …
The glucocorticoid toxicity index: Measuring change in glucocorticoid toxicity over time.
Stone JH, McDowell PJ, Jayne DRW, Merkel PA, Robson J, Patel NJ, Zhang Y, Yue H, Bekker P, Heaney LG. Stone JH, et al. Semin Arthritis Rheum. 2022 Aug;55:152010. doi: 10.1016/j.semarthrit.2022.152010. Epub 2022 Apr 15. Semin Arthritis Rheum. 2022. PMID: 35486995 Free article. Review.
Glucocorticoids (GCs) have been the cornerstone of treating dozens of inflammatory conditions for more than seven decades. GC toxicity is ubiquitous in both clinical trials and clinical practice, and toxicities associated with GC use are central to the experience of …
Glucocorticoids (GCs) have been the cornerstone of treating dozens of inflammatory conditions for more than seven decades. GC toxicity is ub …
Strength training and aerobic exercise training for muscle disease.
Voet NB, van der Kooi EL, van Engelen BG, Geurts AC. Voet NB, et al. Cochrane Database Syst Rev. 2019 Dec 6;12(12):CD003907. doi: 10.1002/14651858.CD003907.pub5. Cochrane Database Syst Rev. 2019. PMID: 31808555 Free PMC article.
SEARCH METHODS: We searched Cochrane Neuromuscular's Specialised Register, CENTRAL, MEDLINE, Embase, and CINAHL in November 2018 and clinical trials registries in December 2018. SELECTION CRITERIA: Randomised controlled trials (RCTs), quasi-RCTs or cross-over RCTs c …
SEARCH METHODS: We searched Cochrane Neuromuscular's Specialised Register, CENTRAL, MEDLINE, Embase, and CINAHL in November 2018 and clin
Ketogenic diet for mitochondrial disease: a systematic review on efficacy and safety.
Zweers H, van Wegberg AMJ, Janssen MCH, Wortmann SB. Zweers H, et al. Orphanet J Rare Dis. 2021 Jul 3;16(1):295. doi: 10.1186/s13023-021-01927-w. Orphanet J Rare Dis. 2021. PMID: 34217336 Free PMC article. Review.
From these eligible reports, cases without a genetically confirmed diagnosis and cases without sufficient data on KD and clinical course were excluded. The remaining studies were included in the qualitative analysis. ...In 4 of 20 cases KD reversed the clinical phen …
From these eligible reports, cases without a genetically confirmed diagnosis and cases without sufficient data on KD and clinical cou …
3,951 results