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Page 1
Thyrotropin Receptor Antibodies-An Overview.
Kotwal A, Stan M. Kotwal A, et al. Ophthalmic Plast Reconstr Surg. 2018 Jul/Aug;34(4S Suppl 1):S20-S27. doi: 10.1097/IOP.0000000000001052. Ophthalmic Plast Reconstr Surg. 2018. PMID: 29771756 Review.
Third generation TRAb assays are useful for therapy selection in GD, prognostic predictions in GO and risk prediction for fetal and neonatal thyrotoxicosis. DISCUSSION: Given the pathogenic role of TRAb, we expect that the future will bring useful evid …
Third generation TRAb assays are useful for therapy selection in GD, prognostic predictions in GO and risk prediction for feta …
Thyroid hyperfunction during pregnancy.
Glinoer D. Glinoer D. Thyroid. 1998 Sep;8(9):859-64. doi: 10.1089/thy.1998.8.859. Thyroid. 1998. PMID: 9777758 Review.
The present report focuses on the two main causes of hyperthyroidism observed in the pregnant state: Graves' disease (GD) and gestational transient thyrotoxicosis. ...Concerning GD, the variable presentations of the disease (women under treatment, in remission, or consider …
The present report focuses on the two main causes of hyperthyroidism observed in the pregnant state: Graves' disease (GD) and gestati …
Measuring TSH receptor antibody to influence treatment choices in Graves' disease.
Hesarghatta Shyamasunder A, Abraham P. Hesarghatta Shyamasunder A, et al. Clin Endocrinol (Oxf). 2017 May;86(5):652-657. doi: 10.1111/cen.13327. Clin Endocrinol (Oxf). 2017. PMID: 28295509 Review.
The second- and third-generation TRAb assays have >95% sensitivity and specificity for the diagnosis of GD and have improved the utility of TRAb to predict relapse. TRAb levels decline with antithyroid drug (ATD) therapy and after thyroidectomy. ...TRAb 5 IU/l in pregna …
The second- and third-generation TRAb assays have >95% sensitivity and specificity for the diagnosis of GD and have improved the utility …
Clinical review: Clinical utility of TSH receptor antibodies.
Barbesino G, Tomer Y. Barbesino G, et al. J Clin Endocrinol Metab. 2013 Jun;98(6):2247-55. doi: 10.1210/jc.2012-4309. Epub 2013 Mar 28. J Clin Endocrinol Metab. 2013. PMID: 23539719 Free PMC article. Review.
However, the role of TRAb measurement in the differential diagnosis of hyperthyroidism, the prediction of remission of GD hyperthyroidism, the prediction of fetal/neonatal thyrotoxicosis, and the clinical assessment of Graves' ophthalmopathy (GO) are c …
However, the role of TRAb measurement in the differential diagnosis of hyperthyroidism, the prediction of remission of GD hyperthyroi …
Neonatal Outcomes of Pregnancies Complicated by Maternal Hyperthyroidism.
Abdullah AA, Ramli N, Yaacob NM, Hussain S. Abdullah AA, et al. J ASEAN Fed Endocr Soc. 2022;37(2):15-22. doi: 10.15605/jafes.037.02.03. Epub 2022 Aug 6. J ASEAN Fed Endocr Soc. 2022. PMID: 36578895 Free PMC article.
CONCLUSION: Neonates born to mothers with hyperthyroidism is uncommon. These babies were observed to have a longer time for normalization of thyroid function tests if their mothers had thyroid antibodies or received anti-thyroid treatment....
CONCLUSION: Neonates born to mothers with hyperthyroidism is uncommon. These babies were observed to have a longer time for normaliza …
Neonatal Screening for Hyperthyroidism Proof of Concept.
Banigé M, Kariyawasam D, Gauthereau V, Luton D, Polak M. Banigé M, et al. J Clin Endocrinol Metab. 2022 Mar 24;107(4):e1374-e1381. doi: 10.1210/clinem/dgab890. J Clin Endocrinol Metab. 2022. PMID: 34894265
Our results have direct implications for clinical care. OBJECTIVE: NH can cause potentially fatal neonatal thyrotoxicosis. Here, we have evaluated the feasibility of neonatal hyperthyroidism screening using the thyroid-stimulating hormone value in dried blood collec …
Our results have direct implications for clinical care. OBJECTIVE: NH can cause potentially fatal neonatal thyrotoxicosis. Her …
The relationship between maternal serum thyroid-stimulating immunoglobulin and fetal and neonatal thyrotoxicosis.
Peleg D, Cada S, Peleg A, Ben-Ami M. Peleg D, et al. Obstet Gynecol. 2002 Jun;99(6):1040-3. doi: 10.1016/s0029-7844(02)01961-0. Obstet Gynecol. 2002. PMID: 12052596
OBJECTIVE: To estimate whether the risk of neonatal thyrotoxicosis was related to the value of maternal thyroid-stimulating immunoglobulin in women with Graves disease. ...RESULTS: Twenty-nine women with a history of Graves disease and positive thyroid-stimulating i …
OBJECTIVE: To estimate whether the risk of neonatal thyrotoxicosis was related to the value of maternal thyroid-stimulating im …
Persistent neonatal thyrotoxicosis in a neonate secondary to a rare thyroid-stimulating hormone receptor activating mutation: case report and literature review.
Watkins MG, Dejkhamron P, Huo J, Vazquez DM, Menon RK. Watkins MG, et al. Endocr Pract. 2008 May-Jun;14(4):479-83. doi: 10.4158/EP.14.4.479. Endocr Pract. 2008. PMID: 18558604 Review.
Analysis of the patient's DNA revealed a heterozygous T-to-C substitution at amino acid 568 in exon 10 (Ile568Thr), which predicts an isoleucine to threonine conversion in the second extracellular loop of TSHR. ...
Analysis of the patient's DNA revealed a heterozygous T-to-C substitution at amino acid 568 in exon 10 (Ile568Thr), which predicts an …
Congenital thyrotoxicosis in premature infants.
Smith C, Thomsett M, Choong C, Rodda C, McIntyre HD, Cotterill AM. Smith C, et al. Clin Endocrinol (Oxf). 2001 Mar;54(3):371-6. doi: 10.1046/j.1365-2265.2001.01173.x. Clin Endocrinol (Oxf). 2001. PMID: 11298090
OBJECTIVES: Graves' disease (GD) complicates 0.1% to 0.2% of pregnancies, but congenital thyrotoxicosis is rare occurring in one in 70 of these pregnancies independent of maternal disease status. Antenatal prediction of affected infants is imprecise; however, maternal hist …
OBJECTIVES: Graves' disease (GD) complicates 0.1% to 0.2% of pregnancies, but congenital thyrotoxicosis is rare occurring in one in 70 of th …
Graves' disease in pregnancy: TSH receptor binding inhibiting immunoglobulins and maternal and neonatal thyroid function.
Mortimer RH, Tyack SA, Galligan JP, Perry-Keene DA, Tan YM. Mortimer RH, et al. Clin Endocrinol (Oxf). 1990 Feb;32(2):141-52. doi: 10.1111/j.1365-2265.1990.tb00850.x. Clin Endocrinol (Oxf). 1990. PMID: 1971773
Neonatal FTI was independently related to umbilical vein TBII (t = 2.29, P = 0.03) and maternal dose of antithyroid drug (t = -2.21, P = 0.03). Neonatal thyrotoxicosis was seen in all four infants (8% of births) of women whose TBII levels at delivery exceeded 70%. . …
Neonatal FTI was independently related to umbilical vein TBII (t = 2.29, P = 0.03) and maternal dose of antithyroid drug (t = -2.21, P = 0.0 …
15 results