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Vasopressin-aquaporin-2 pathway: recent advances in understanding water balance disorders.
Ranieri M, Di Mise A, Tamma G, Valenti G. Ranieri M, et al. F1000Res. 2019 Feb 4;8:F1000 Faculty Rev-149. doi: 10.12688/f1000research.16654.1. eCollection 2019. F1000Res. 2019. PMID: 30800291 Free PMC article. Review.
This review highlights some of the new insights and recent advances in therapeutic intervention targeting the dysfunctions in the vasopressin-AQP2 pathway causing diseases characterized by water balance disorders such as congenital nephrogenic diabetes insipidus, syndrome of inap …
This review highlights some of the new insights and recent advances in therapeutic intervention targeting the dysfunctions in the vasopressi …
Germline-Derived Gain-of-Function Variants of Gsalpha-Coding GNAS Gene Identified in Nephrogenic Syndrome of Inappropriate Antidiuresis.
Miyado M, Fukami M, Takada S, Terao M, Nakabayashi K, Hata K, Matsubara Y, Tanaka Y, Sasaki G, Nagasaki K, Shiina M, Ogata K, Masunaga Y, Saitsu H, Ogata T. Miyado M, et al. J Am Soc Nephrol. 2019 May;30(5):877-889. doi: 10.1681/ASN.2018121268. Epub 2019 Apr 8. J Am Soc Nephrol. 2019. PMID: 30962325 Free PMC article.
METHODS: We performed whole-exome sequencing in two families with dominantly inherited nephrogenic syndrome of inappropriate antidiuresis (NSIAD) as a salient phenotype after excluding a gain-of-function variant of AVPR2 and functional studies f …
METHODS: We performed whole-exome sequencing in two families with dominantly inherited nephrogenic syndrome of inapp …
Vasopressin receptor 2 mutations in the nephrogenic syndrome of inappropriate antidiuresis show different mechanisms of constitutive activation for G protein coupled receptors.
Vezzi V, Ambrosio C, Grò MC, Molinari P, Süral G, Costa T, Onaran HO, Cotecchia S. Vezzi V, et al. Sci Rep. 2020 Jun 4;10(1):9111. doi: 10.1038/s41598-020-65996-w. Sci Rep. 2020. PMID: 32499611 Free PMC article.
Vasopressin receptor 2 (V2R) mutations causing the nephrogenic syndrome of inappropriate antidiuresis (NSIAD) can generate two constitutively active receptor phenotypes. ...
Vasopressin receptor 2 (V2R) mutations causing the nephrogenic syndrome of inappropriate antidiuresis (NS …
Characteristics, prevalence, risk factors, and underlying mechanism of hyponatremia in elderly patients treated with antidepressants: a cross-sectional study.
Mannesse CK, Jansen PA, Van Marum RJ, Sival RC, Kok RM, Haffmans PM, Egberts TC. Mannesse CK, et al. Maturitas. 2013 Dec;76(4):357-63. doi: 10.1016/j.maturitas.2013.08.010. Epub 2013 Sep 7. Maturitas. 2013. PMID: 24094459
Patients with previous hyponatremia, weight <60 kg, and psychosis were at risk. Beside SIADH, the nephrogenic syndrome of inappropriate antidiuresis, in which ADH secretion was normal, is postulated as an underlying mechanism. ...
Patients with previous hyponatremia, weight <60 kg, and psychosis were at risk. Beside SIADH, the nephrogenic syndrome o …