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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1953 10
1954 8
1955 7
1956 7
1957 11
1958 21
1959 5
1963 1
1964 7
1965 24
1966 39
1967 63
1968 69
1969 77
1970 82
1971 88
1972 96
1973 140
1974 141
1975 200
1976 148
1977 142
1978 176
1979 218
1980 226
1981 220
1982 207
1983 335
1984 312
1985 315
1986 346
1987 323
1988 365
1989 377
1990 387
1991 409
1992 461
1993 489
1994 581
1995 524
1996 546
1997 592
1998 675
1999 729
2000 741
2001 718
2002 794
2003 889
2004 899
2005 1002
2006 1081
2007 1105
2008 1208
2009 1255
2010 1286
2011 1411
2012 1503
2013 1601
2014 1569
2015 1549
2016 1600
2017 1664
2018 1593
2019 1652
2020 1759
2021 1709
2022 1595
2023 1446
2024 657

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38,546 results

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Quoted phrase not found in phrase index: "Neurodevelopmental disorder with cerebellar atrophy and with or without seizures"
Page 1
Novel Therapeutics for Neonatal Seizures.
Ziobro JM, Eschbach K, Shellhaas RA. Ziobro JM, et al. Neurotherapeutics. 2021 Jul;18(3):1564-1581. doi: 10.1007/s13311-021-01085-8. Epub 2021 Aug 12. Neurotherapeutics. 2021. PMID: 34386906 Free PMC article. Review.
Neonatal seizures are a common neurologic emergency for which therapies have not significantly changed in decades. ...We present emerging therapies in clinical and preclinical development for the treatment of acute symptomatic neonatal seizures. ...
Neonatal seizures are a common neurologic emergency for which therapies have not significantly changed in decades. ...We present emer …
Cannabidiol in the Treatment of Epilepsy.
von Wrede R, Helmstaedter C, Surges R. von Wrede R, et al. Clin Drug Investig. 2021 Mar;41(3):211-220. doi: 10.1007/s40261-021-01003-y. Epub 2021 Feb 9. Clin Drug Investig. 2021. PMID: 33559102 Free PMC article. Review.
Anecdotal reports addressing the successful seizure treatment of severe epilepsies with cannabidiol (CBD) have increased both public interest and academic research. Placebo-controlled, randomized, controlled trials proved the efficacy of pharmaceutical-grade CBD in …
Anecdotal reports addressing the successful seizure treatment of severe epilepsies with cannabidiol (CBD) have increased both public …
Seizures, Status Epilepticus, and Continuous EEG in the Intensive Care Unit.
Rosenthal ES. Rosenthal ES. Continuum (Minneap Minn). 2021 Oct 1;27(5):1321-1343. doi: 10.1212/CON.0000000000001012. Continuum (Minneap Minn). 2021. PMID: 34618762 Review.
PURPOSE OF REVIEW: This article discusses the evolving definitions of seizures and status epilepticus in the critical care environment and the role of critical care EEG in both diagnosing seizure activity and serving as a predictive biomarker of clinical traj …
PURPOSE OF REVIEW: This article discusses the evolving definitions of seizures and status epilepticus in the critical care environmen …
Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial.
Kotulska K, Kwiatkowski DJ, Curatolo P, Weschke B, Riney K, Jansen F, Feucht M, Krsek P, Nabbout R, Jansen AC, Wojdan K, Sijko K, Głowacka-Walas J, Borkowska J, Sadowski K, Domańska-Pakieła D, Moavero R, Hertzberg C, Hulshof H, Scholl T, Benova B, Aronica E, de Ridder J, Lagae L, Jóźwiak S; EPISTOP Investigators. Kotulska K, et al. Ann Neurol. 2021 Feb;89(2):304-314. doi: 10.1002/ana.25956. Epub 2020 Nov 27. Ann Neurol. 2021. PMID: 33180985 Free PMC article. Clinical Trial.
At 6 sites, subjects were randomly allocated to treatment in a 1:1 ratio in a randomized controlled trial (RCT). At 4 sites, treatment allocation was fixed; this was denoted an open-label trial (OLT). Subjects were followed until 2 years of age. The pr …
At 6 sites, subjects were randomly allocated to treatment in a 1:1 ratio in a randomized controlled trial (RCT). At 4 s …
Ketogenic diet in pediatric seizures: a randomized controlled trial review and meta-analysis.
Pizzo F, Collotta AD, Di Nora A, Costanza G, Ruggieri M, Falsaperla R. Pizzo F, et al. Expert Rev Neurother. 2022 Feb;22(2):169-177. doi: 10.1080/14737175.2022.2030220. Epub 2022 Feb 25. Expert Rev Neurother. 2022. PMID: 35144527
This systematic review and meta-analysis aimed to assess the efficacy of the ketogenic diet on seizures frequency in children. METHODS: We reviewed the literature using Cochrane, EMBASE, MEDLINE, and highly qualified journals.Randomized controlled trials were chosen …
This systematic review and meta-analysis aimed to assess the efficacy of the ketogenic diet on seizures frequency in children. METHOD …
Non-electroencephalography-based seizure detection.
Beniczky S, Jeppesen J. Beniczky S, et al. Curr Opin Neurol. 2019 Apr;32(2):198-204. doi: 10.1097/WCO.0000000000000658. Curr Opin Neurol. 2019. PMID: 30664069 Review.
PURPOSE OF REVIEW: There is need for automated seizure detection using mobile or wearable devices, for objective seizure documentation and decreasing morbidity and mortality associated with seizures. ...We found limited evidence for detection of motor seiz …
PURPOSE OF REVIEW: There is need for automated seizure detection using mobile or wearable devices, for objective seizure docum …
Safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial.
Peter-Derex L, Philippeau F, Garnier P, André-Obadia N, Boulogne S, Catenoix H, Convers P, Mazzola L, Gouttard M, Esteban M, Fontaine J, Mechtouff L, Ong E, Cho TH, Nighoghossian N, Perreton N, Termoz A, Haesebaert J, Schott AM, Rabilloud M, Pivot C, Dhelens C, Filip A, Berthezène Y, Rheims S, Boutitie F, Derex L. Peter-Derex L, et al. Lancet Neurol. 2022 Sep;21(9):781-791. doi: 10.1016/S1474-4422(22)00235-6. Lancet Neurol. 2022. PMID: 35963261 Clinical Trial.
We aimed to assess whether prophylactic levetiracetam would reduce the risk of acute seizures in patients with intracerebral haemorrhage. METHODS: The double-blind, randomised, placebo-controlled, phase 3 PEACH trial was conducted at three stroke units in Fra …
We aimed to assess whether prophylactic levetiracetam would reduce the risk of acute seizures in patients with intracerebral haemorrh …
Treatment of benzodiazepine-resistant status epilepticus: Systematic review and network meta-analyses.
Jain P, Aneja S, Cunningham J, Arya R, Sharma S. Jain P, et al. Seizure. 2022 Nov;102:74-82. doi: 10.1016/j.seizure.2022.09.017. Epub 2022 Sep 26. Seizure. 2022. PMID: 36209676 Free article. Review.
Outcomes including seizure cessation within 60 min, seizure freedom for 24 h, death, respiratory depression warranting intubation and cardiovascular instability were studied. ...CONCLUSIONS: Based on low quality evidence, phenobarbital appears to be the most effecti …
Outcomes including seizure cessation within 60 min, seizure freedom for 24 h, death, respiratory depression warranting intubat …
25 years of advances in the definition, classification and treatment of status epilepticus.
Trinka E, Kälviäinen R. Trinka E, et al. Seizure. 2017 Jan;44:65-73. doi: 10.1016/j.seizure.2016.11.001. Epub 2016 Nov 14. Seizure. 2017. PMID: 27890484 Free article. Review.
RESULTS: SE is now defined as "a condition resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms, which lead to abnormally, prolonged seizures (after time point t1). It is a condition, which can …
RESULTS: SE is now defined as "a condition resulting either from the failure of the mechanisms responsible for seizure termination or …
Intranasal midazolam versus intravenous/rectal benzodiazepines for acute seizure control in children: A systematic review and meta-analysis.
Chhabra R, Gupta R, Gupta LK. Chhabra R, et al. Epilepsy Behav. 2021 Dec;125:108390. doi: 10.1016/j.yebeh.2021.108390. Epub 2021 Nov 2. Epilepsy Behav. 2021. PMID: 34740090 Review.
METHODS: PubMed, google scholar, websites clinicaltrials.gov and the WHO-international clinical trials registry platform, were searched. Randomized controlled/prospective randomized trials comparing IN midazolam against IV/rectal BDZ in the treatment of acute …
METHODS: PubMed, google scholar, websites clinicaltrials.gov and the WHO-international clinical trials registry platform, were search …
38,546 results
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