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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1953 10
1954 8
1955 7
1956 8
1957 12
1958 21
1959 5
1963 1
1964 8
1965 26
1966 40
1967 65
1968 69
1969 77
1970 85
1971 94
1972 97
1973 147
1974 144
1975 204
1976 153
1977 145
1978 181
1979 226
1980 232
1981 229
1982 210
1983 346
1984 319
1985 328
1986 351
1987 332
1988 377
1989 385
1990 404
1991 424
1992 471
1993 502
1994 607
1995 539
1996 568
1997 615
1998 701
1999 755
2000 783
2001 735
2002 831
2003 919
2004 927
2005 1031
2006 1126
2007 1145
2008 1243
2009 1294
2010 1332
2011 1451
2012 1554
2013 1666
2014 1626
2015 1598
2016 1642
2017 1720
2018 1645
2019 1705
2020 1806
2021 1763
2022 1642
2023 1497
2024 735

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39,872 results

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Quoted phrase not found in phrase index: "Neuromuscular disease and ocular or auditory anomalies with or without seizures"
Page 1
Novel Therapeutics for Neonatal Seizures.
Ziobro JM, Eschbach K, Shellhaas RA. Ziobro JM, et al. Neurotherapeutics. 2021 Jul;18(3):1564-1581. doi: 10.1007/s13311-021-01085-8. Epub 2021 Aug 12. Neurotherapeutics. 2021. PMID: 34386906 Free PMC article. Review.
Neonatal seizures are a common neurologic emergency for which therapies have not significantly changed in decades. ...We present emerging therapies in clinical and preclinical development for the treatment of acute symptomatic neonatal seizures. ...
Neonatal seizures are a common neurologic emergency for which therapies have not significantly changed in decades. ...We present emer …
Cannabidiol in the Treatment of Epilepsy.
von Wrede R, Helmstaedter C, Surges R. von Wrede R, et al. Clin Drug Investig. 2021 Mar;41(3):211-220. doi: 10.1007/s40261-021-01003-y. Epub 2021 Feb 9. Clin Drug Investig. 2021. PMID: 33559102 Free PMC article. Review.
Anecdotal reports addressing the successful seizure treatment of severe epilepsies with cannabidiol (CBD) have increased both public interest and academic research. Placebo-controlled, randomized, controlled trials proved the efficacy of pharmaceutical-grade CBD in …
Anecdotal reports addressing the successful seizure treatment of severe epilepsies with cannabidiol (CBD) have increased both public …
Seizures, Status Epilepticus, and Continuous EEG in the Intensive Care Unit.
Rosenthal ES. Rosenthal ES. Continuum (Minneap Minn). 2021 Oct 1;27(5):1321-1343. doi: 10.1212/CON.0000000000001012. Continuum (Minneap Minn). 2021. PMID: 34618762 Review.
PURPOSE OF REVIEW: This article discusses the evolving definitions of seizures and status epilepticus in the critical care environment and the role of critical care EEG in both diagnosing seizure activity and serving as a predictive biomarker of clinical traj …
PURPOSE OF REVIEW: This article discusses the evolving definitions of seizures and status epilepticus in the critical care environmen …
Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial.
Kotulska K, Kwiatkowski DJ, Curatolo P, Weschke B, Riney K, Jansen F, Feucht M, Krsek P, Nabbout R, Jansen AC, Wojdan K, Sijko K, Głowacka-Walas J, Borkowska J, Sadowski K, Domańska-Pakieła D, Moavero R, Hertzberg C, Hulshof H, Scholl T, Benova B, Aronica E, de Ridder J, Lagae L, Jóźwiak S; EPISTOP Investigators. Kotulska K, et al. Ann Neurol. 2021 Feb;89(2):304-314. doi: 10.1002/ana.25956. Epub 2020 Nov 27. Ann Neurol. 2021. PMID: 33180985 Free PMC article. Clinical Trial.
At 6 sites, subjects were randomly allocated to treatment in a 1:1 ratio in a randomized controlled trial (RCT). At 4 sites, treatment allocation was fixed; this was denoted an open-label trial (OLT). Subjects were followed until 2 years of age. The pr …
At 6 sites, subjects were randomly allocated to treatment in a 1:1 ratio in a randomized controlled trial (RCT). At 4 s …
Myasthenia Gravis and Congenital Myasthenic Syndromes.
Ciafaloni E. Ciafaloni E. Continuum (Minneap Minn). 2019 Dec;25(6):1767-1784. doi: 10.1212/CON.0000000000000800. Continuum (Minneap Minn). 2019. PMID: 31794470 Review.
PURPOSE OF REVIEW: Myasthenia gravis (MG) is an autoimmune neuromuscular disease that causes fluctuating weakness in ocular, bulbar, and limb muscles and can, in 15% of cases, cause myasthenic crisis, a neurologic emergency characterized by respiratory failur …
PURPOSE OF REVIEW: Myasthenia gravis (MG) is an autoimmune neuromuscular disease that causes fluctuating weakness in ocular …
Safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial.
Peter-Derex L, Philippeau F, Garnier P, André-Obadia N, Boulogne S, Catenoix H, Convers P, Mazzola L, Gouttard M, Esteban M, Fontaine J, Mechtouff L, Ong E, Cho TH, Nighoghossian N, Perreton N, Termoz A, Haesebaert J, Schott AM, Rabilloud M, Pivot C, Dhelens C, Filip A, Berthezène Y, Rheims S, Boutitie F, Derex L. Peter-Derex L, et al. Lancet Neurol. 2022 Sep;21(9):781-791. doi: 10.1016/S1474-4422(22)00235-6. Lancet Neurol. 2022. PMID: 35963261 Clinical Trial.
We aimed to assess whether prophylactic levetiracetam would reduce the risk of acute seizures in patients with intracerebral haemorrhage. METHODS: The double-blind, randomised, placebo-controlled, phase 3 PEACH trial was conducted at three stroke units in Fra …
We aimed to assess whether prophylactic levetiracetam would reduce the risk of acute seizures in patients with intracerebral haemorrh …
Ketogenic diet in pediatric seizures: a randomized controlled trial review and meta-analysis.
Pizzo F, Collotta AD, Di Nora A, Costanza G, Ruggieri M, Falsaperla R. Pizzo F, et al. Expert Rev Neurother. 2022 Feb;22(2):169-177. doi: 10.1080/14737175.2022.2030220. Epub 2022 Feb 25. Expert Rev Neurother. 2022. PMID: 35144527
This systematic review and meta-analysis aimed to assess the efficacy of the ketogenic diet on seizures frequency in children. METHODS: We reviewed the literature using Cochrane, EMBASE, MEDLINE, and highly qualified journals.Randomized controlled trials were chosen …
This systematic review and meta-analysis aimed to assess the efficacy of the ketogenic diet on seizures frequency in children. METHOD …
Cenobamate: A Review of its Pharmacological Properties, Clinical Efficacy and Tolerability Profile in the Treatment of Epilepsy.
Barbieri MA, Perucca E, Spina E, Rota P, Franco V. Barbieri MA, et al. CNS Neurol Disord Drug Targets. 2023;22(3):394-403. doi: 10.2174/1871527321666220113110044. CNS Neurol Disord Drug Targets. 2023. PMID: 35049441 Review.
Cenobamate is a CYP2C19 inhibitor and an inducer of CYP3A4 and CYP2B6, and consequently, it can cause a number of drug-drug interactions. Efficacy and safety have been evaluated in two randomized, double-blind, placebo-controlled adjunctive therapy trials in adults with fo …
Cenobamate is a CYP2C19 inhibitor and an inducer of CYP3A4 and CYP2B6, and consequently, it can cause a number of drug-drug interactions. Ef …
25 years of advances in the definition, classification and treatment of status epilepticus.
Trinka E, Kälviäinen R. Trinka E, et al. Seizure. 2017 Jan;44:65-73. doi: 10.1016/j.seizure.2016.11.001. Epub 2016 Nov 14. Seizure. 2017. PMID: 27890484 Free article. Review.
RESULTS: SE is now defined as "a condition resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms, which lead to abnormally, prolonged seizures (after time point t1). It is a condition, which can …
RESULTS: SE is now defined as "a condition resulting either from the failure of the mechanisms responsible for seizure termination or …
Treatment of benzodiazepine-resistant status epilepticus: Systematic review and network meta-analyses.
Jain P, Aneja S, Cunningham J, Arya R, Sharma S. Jain P, et al. Seizure. 2022 Nov;102:74-82. doi: 10.1016/j.seizure.2022.09.017. Epub 2022 Sep 26. Seizure. 2022. PMID: 36209676 Free article. Review.
Outcomes including seizure cessation within 60 min, seizure freedom for 24 h, death, respiratory depression warranting intubation and cardiovascular instability were studied. ...CONCLUSIONS: Based on low quality evidence, phenobarbital appears to be the most effecti …
Outcomes including seizure cessation within 60 min, seizure freedom for 24 h, death, respiratory depression warranting intubat …
39,872 results
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