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Juvenile xanthogranuloma and nevus anemicus in the diagnosis of neurofibromatosis type 1.
Ferrari F, Masurel A, Olivier-Faivre L, Vabres P. Ferrari F, et al. JAMA Dermatol. 2014 Jan;150(1):42-6. doi: 10.1001/jamadermatol.2013.6434. JAMA Dermatol. 2014. PMID: 24258576
However, they are of limited value before the age of 2 years. Juvenile xanthogranuloma (JXG) and nevus anemicus (NA) are commonly observed in children with NF1 and may be useful diagnostic clues. ...No patient with JXG developed chronic myelomonocytic leukemi …
However, they are of limited value before the age of 2 years. Juvenile xanthogranuloma (JXG) and nevus anemicus (NA) are commo …
Neurofibromatosis Type 1: Diagnostic Timelines in Children.
García-Martínez FJ, Hernández-Martín A. García-Martínez FJ, et al. Actas Dermosifiliogr. 2023 Mar;114(3):187-193. doi: 10.1016/j.ad.2022.10.036. Epub 2022 Nov 9. Actas Dermosifiliogr. 2023. PMID: 36370836 Free article. English, Spanish.
The aims of this study were to estimate diagnostic delays in children without a family history of NF1 and to examine the effects of using cafe au lait macules and skin fold freckling as a single diagnostic criterion. PATIENTS AND METHODS: Retrospective, descriptive, observatio
The aims of this study were to estimate diagnostic delays in children without a family history of NF1 and to examine the effects of using ca …
Nevus anemicus: a distinctive cutaneous finding in neurofibromatosis type 1.
Hernández-Martín A, García-Martínez FJ, Duat A, López-Martín I, Noguera-Morel L, Torrelo A. Hernández-Martín A, et al. Pediatr Dermatol. 2015 May-Jun;32(3):342-7. doi: 10.1111/pde.12525. Epub 2015 Feb 18. Pediatr Dermatol. 2015. PMID: 25690591
Nevus anemicus (NA) is a cutaneous anomaly characterized by pale, well-defined patches with limited vascularization after rubbing. ...We sought to characterize the prevalence and clinical features of patients with NA and NF1. We conducted an observational pro
Nevus anemicus (NA) is a cutaneous anomaly characterized by pale, well-defined patches with limited vascularization after rubb
Cutaneous Manifestations not Considered Diagnostic Criteria for Neurofibromatosis Type 1. A Case-Control Study.
García-Martínez FJ, Duat-Rodríguez A, Andrés Esteban E, Torrelo A, Noguera Morel L, Hernández-Martín A. García-Martínez FJ, et al. Actas Dermosifiliogr. 2022 Nov-Dec;113(10):923-929. doi: 10.1016/j.ad.2022.05.014. Epub 2022 May 27. Actas Dermosifiliogr. 2022. PMID: 35636506 Free article. English, Spanish.
PATIENTS AND METHODS: Case-control study, matched by age groups, in which 108 patients with a diagnosis of NF1 and 137 healthy controls were included. RESULTS: The prevalence of nevus anemicus (NA) (p<0.001) and juvenile xanthogranulomas (JXG) (p<0.001) was si …
PATIENTS AND METHODS: Case-control study, matched by age groups, in which 108 patients with a diagnosis of NF1 and 137 healthy controls were …
Cutaneous Manifestations not Considered Diagnostic Criteria for Neurofibromatosis Type 1. A Case-Control Study.
García-Martínez FJ, Duat-Rodríguez A, Andrés Esteban E, Torrelo A, Noguera Morel L, Hernández-Martín A. García-Martínez FJ, et al. Actas Dermosifiliogr. 2022 Nov-Dec;113(10):T923-T929. doi: 10.1016/j.ad.2022.09.011. Epub 2022 Sep 24. Actas Dermosifiliogr. 2022. PMID: 36162491 Free article. English, Spanish.
PATIENTS AND METHODS: Case-control study, matched by age groups, in which 108 patients with a diagnosis of NF1 and 137 healthy controls were included. RESULTS: The prevalence of nevus anemicus (NA) (P<.001) and juvenile xanthogranulomas (JXG) (P<.001) was sign …
PATIENTS AND METHODS: Case-control study, matched by age groups, in which 108 patients with a diagnosis of NF1 and 137 healthy controls were …
An Update on Neurofibromatosis Type 1: Not Just Café-au-Lait Spots and Freckling. Part II. Other Skin Manifestations Characteristic of NF1. NF1 and Cancer.
Hernández-Martín A, Duat-Rodríguez A. Hernández-Martín A, et al. Actas Dermosifiliogr. 2016 Jul-Aug;107(6):465-73. doi: 10.1016/j.ad.2016.01.009. Epub 2016 Mar 5. Actas Dermosifiliogr. 2016. PMID: 26956402 Free article. Review. English, Spanish.
Although the genetic locus of NF1 was identified on chromosome 17 in 1987, diagnosis of the disease is still based primarily on clinical observations. The 7 diagnostic criteria of the National Institutes of Health, which were established in 1988, include 3 skin manifestati …
Although the genetic locus of NF1 was identified on chromosome 17 in 1987, diagnosis of the disease is still based primarily on clinical …
Nevus Anemicus As an Additional Diagnostic Marker of Neurofibromatosis Type 1 in Childhood.
Vaassen P, Rosenbaum T. Vaassen P, et al. Neuropediatrics. 2016 Jun;47(3):190-3. doi: 10.1055/s-0036-1579786. Epub 2016 Mar 28. Neuropediatrics. 2016. PMID: 27019377
Therefore, we tried to identify additional clinical signs suggestive of NF1. We observed that nevi anemici (NA) occur with increased frequency in NF1 patients. ...We hypothesize that an imbalance between alpha- and beta-adrenergic receptors, resulting in increased alpha-ad …
Therefore, we tried to identify additional clinical signs suggestive of NF1. We observed that nevi anemici (NA) occur with increased …
Loss of cutaneous delayed hypersensitivity reactions in nevus anemicus. Evidence for close concordance of cutaneous delayed hypersensitivity and endothelial E-selectin expression.
Mizutani H, Ohyanagi S, Umeda Y, Shimizu M, Kupper TS. Mizutani H, et al. Arch Dermatol. 1997 May;133(5):617-20. Arch Dermatol. 1997. PMID: 9158415
BACKGROUND: The relationship of adhesion molecules in the dermis to immunologically mediated cutaneous inflammation can be understood by focusing on a serendipitous phenomenon: a lack of dermatitis within the margins of a nevus anemicus (NA) in generalized contact d …
BACKGROUND: The relationship of adhesion molecules in the dermis to immunologically mediated cutaneous inflammation can be understood by foc …
Adnexal polyp in a newborn baby.
Mapelli ET, Menni S, Gualandri L, Agape E, Cerri A. Mapelli ET, et al. Dermatol Online J. 2015 May 18;21(5):13030/qt85g9w1jb. Dermatol Online J. 2015. PMID: 26295856
Presented here is the case of a newborn baby with two simultaneous birthmarks: an adnexal polyp and a nevus anemicus. Adnexal polyps are considered an uncommon clinical observation...
Presented here is the case of a newborn baby with two simultaneous birthmarks: an adnexal polyp and a nevus anemicus. Adnexal …