Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 11
1973 6
1974 6
1975 14
1976 8
1977 5
1978 6
1979 28
1980 16
1981 16
1982 17
1983 19
1984 15
1985 19
1986 21
1987 14
1988 9
1989 14
1990 16
1991 10
1992 17
1993 6
1994 8
1995 9
1996 8
1997 13
1998 7
1999 10
2000 3
2001 7
2002 7
2003 2
2004 8
2005 5
2006 4
2007 5
2008 7
2009 4
2010 2
2011 6
2012 4
2013 5
2014 11
2015 5
2016 4
2017 9
2018 4
2019 5
2020 5
2021 6
2022 7
2023 3
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

464 results

Results by year

Filters applied: . Clear all
Page 1
Ergotamine and nicergoline - facts and myths.
Zajdel P, Bednarski M, Sapa J, Nowak G. Zajdel P, et al. Pharmacol Rep. 2015 Apr;67(2):360-3. doi: 10.1016/j.pharep.2014.10.010. Epub 2014 Oct 30. Pharmacol Rep. 2015. PMID: 25712664 Review.
Although introduction of triptans marginalized use of ergotamine, nicergoline is used in cerebral metabolic-vascular disorders, and dementia. Additionally, nicergoline exhibits a safety profile comparable to that of placebo, and none of the reviewed studies reported …
Although introduction of triptans marginalized use of ergotamine, nicergoline is used in cerebral metabolic-vascular disorders, and d …
Therapeutic use of nicergoline.
Winblad B, Fioravanti M, Dolezal T, Logina I, Milanov IG, Popescu DC, Solomon A. Winblad B, et al. Clin Drug Investig. 2008;28(9):533-52. doi: 10.2165/00044011-200828090-00001. Clin Drug Investig. 2008. PMID: 18666801 Review.
The ergot alkaloid derivative nicergoline became clinically available about 35 years ago in the 1970s. ...Open-label evaluations suggest that nicergoline may also be valuable in glaucoma, depression and peripheral arterio-pathy. ...
The ergot alkaloid derivative nicergoline became clinically available about 35 years ago in the 1970s. ...Open-label evaluations sugg …
Safety of nicergoline as an agent for management of cognitive function disorders.
Saletu B, Garg A, Shoeb A. Saletu B, et al. Biomed Res Int. 2014;2014:610103. doi: 10.1155/2014/610103. Epub 2014 Aug 28. Biomed Res Int. 2014. PMID: 25243157 Free PMC article. Review.
Nicergoline is a semisynthetic ergot derivative and has a selective alpha-1A adrenergic receptor blocking property and also other additional mechanisms of actions, both in the brain and in the periphery. ...However, concerns about its safety have been raised, especially af
Nicergoline is a semisynthetic ergot derivative and has a selective alpha-1A adrenergic receptor blocking property and also other add
Neurotrophic keratopathy: current challenges and future prospects.
NaPier E, Camacho M, McDevitt TF, Sweeney AR. NaPier E, et al. Ann Med. 2022 Dec;54(1):666-673. doi: 10.1080/07853890.2022.2045035. Ann Med. 2022. PMID: 35243932 Free PMC article. Review.
New therapies, such as matrix regenerating therapy, plasma rich in growth factors, Thymosin beta4, Substance P/Insulin like growth factor-1, and nicergoline represent exciting future options.KEY MESSAGESNeurotrophic keratopathy is a rare degenerative disease defined by dec …
New therapies, such as matrix regenerating therapy, plasma rich in growth factors, Thymosin beta4, Substance P/Insulin like growth factor-1, …
A clinical trial of nicergoline to prevent temporary threshold shift.
Klamkam P, Pagcharoenpol R, Treesaranuwattana T, Silpsrikul P, Jaruchinda P, Wasuwat P, Suwannahitatorn P. Klamkam P, et al. Laryngoscope Investig Otolaryngol. 2022 Jan 25;7(2):515-522. doi: 10.1002/lio2.746. eCollection 2022 Apr. Laryngoscope Investig Otolaryngol. 2022. PMID: 35434325 Free PMC article.
OBJECTIVE: To evaluate the effectiveness of nicergoline to prevent temporary threshold shift (TTS) in military personnel. ...The mean different threshold of participants receiving nicergoline showed negative STS in all tested frequencies without statistical signific …
OBJECTIVE: To evaluate the effectiveness of nicergoline to prevent temporary threshold shift (TTS) in military personnel. ...The mean …
[The use nicergoline in the treatment of diabetes mellitus].
Popova IV, Karpenko AA. Popova IV, et al. Angiol Sosud Khir. 2017;23(3):39-46. Angiol Sosud Khir. 2017. PMID: 28902812 Review. Russian.
Presented herein is a literature review aimed at investigating the appropriateness and possibility of using nicergoline (sermion) for treatment of patients suffering from diabetes mellitus. ...Special attention is given to the analysis of efficacy of nicergoline in …
Presented herein is a literature review aimed at investigating the appropriateness and possibility of using nicergoline (sermion) for …
Role of nicergoline in corneal wound healing in diabetic rats.
Portela ALBM, Moreno RN, Ribeiro MHML, de Andrade FM, Alves YV, Alves M, Lira RPC. Portela ALBM, et al. BMC Ophthalmol. 2021 Feb 9;21(1):77. doi: 10.1186/s12886-021-01835-4. BMC Ophthalmol. 2021. PMID: 33563243 Free PMC article.
BACKGROUND: To investigate the effect of nicergoline on the rate of complete corneal ulcer reepithelialization (CCUR) in diabetic rats with diabetic keratopathy. ...RESULTS: When compared, 4 of the 24 rats (17%) in the placebo group and 12 of the 24 rats (50%) in the ni
BACKGROUND: To investigate the effect of nicergoline on the rate of complete corneal ulcer reepithelialization (CCUR) in diabetic rat …
Use of Nicergoline as Adjunctive Treatment of Neurotrophic Keratitis in Routine Clinical Practice: A Case Series.
Miguel-Escuder L, Rocha-de-Lossada C, Sabater-Cruz N, Sánchez-González JM, Spencer F, Marín-Martínez S, Batlle-Ferrando S, Carreras Castañer X, Torras J, Peraza-Nieves J. Miguel-Escuder L, et al. Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1926-1930. doi: 10.1080/09273948.2021.1976214. Epub 2021 Oct 12. Ocul Immunol Inflamm. 2022. PMID: 34637676
Patients with a epithelial defect or corneal ulcer due to NK were treated with oral nicergoline. RESULTS/SERIAL CASES: Complete corneal healing was observed in 10 (71.4%) of the 14 patients after 25.6 26.60 days (range 7-90) with nicergoline. In three (21.5%) patien …
Patients with a epithelial defect or corneal ulcer due to NK were treated with oral nicergoline. RESULTS/SERIAL CASES: Complete corne …
A systematic review and meta-analysis assessing adverse event profile and tolerability of nicergoline.
Fioravanti M, Nakashima T, Xu J, Garg A. Fioravanti M, et al. BMJ Open. 2014 Jul 30;4(7):e005090. doi: 10.1136/bmjopen-2014-005090. BMJ Open. 2014. PMID: 25079927 Free PMC article. Review.
Frequency of hypotension and hot flushes was slightly higher in the nicergoline group but the difference was non-significant. None of the studies reported any incidence of fibrosis or ergotism with nicergoline treatment. ...This systematic review and meta-analysis s …
Frequency of hypotension and hot flushes was slightly higher in the nicergoline group but the difference was non-significant. None of …
Efficacy of nicergoline in dementia and other age associated forms of cognitive impairment.
Fioravanti M, Flicker L. Fioravanti M, et al. Cochrane Database Syst Rev. 2001;2001(4):CD003159. doi: 10.1002/14651858.CD003159. Cochrane Database Syst Rev. 2001. PMID: 11687175 Free PMC article. Review.
This scale has a maximum of 133 points. The therapeutic effects of nicergoline seem to be evident by 2 months of treatment and maintained for 6 months. ...REVIEWER'S CONCLUSIONS: The clinical studies on nicergoline were carried out with diverse criteria and modaliti …
This scale has a maximum of 133 points. The therapeutic effects of nicergoline seem to be evident by 2 months of treatment and mainta …
464 results