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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1981 1
1984 1
1986 1
1987 1
1991 1
1998 1
2002 1
2003 2
2004 1
2006 1
2007 2
2008 1
2009 2
2010 1
2011 4
2012 4
2014 1
2017 1
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2019 1
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2023 1
2024 0

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30 results

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Page 1
A novel solid phase extraction sample preparation method for sensitively determining doxepin and N-nordoxepin in human plasma and its application in a bioequivalence study in healthy Chinese volunteers.
Zheng B, Chen L, Zheng T, Hou L, Huang X, Li C, Wang X, Fang Q, Chen J, Tang Z, Li Z, Ouyang D. Zheng B, et al. Anal Methods. 2022 Jun 9;14(22):2168-2178. doi: 10.1039/d2ay00129b. Anal Methods. 2022. PMID: 35608048
Chromatography separation was performed on a Waters ACQUITY UPLC BEH C18 column (2.1 100 mm, 1.7 mum) and a mobile phase consisting of 70% of mobile phase A (0.1% formic acid and 10 mM ammonium formate) and 30% mobile phase B (0.1% formic acid in acetonitrile) at a flow rate of 0 …
Chromatography separation was performed on a Waters ACQUITY UPLC BEH C18 column (2.1 100 mm, 1.7 mum) and a mobile phase consisting of 70% o …
High-throughput protein precipitation method with 96-well plate for determination of doxepin and nordoxepin in human plasma using LC-MS/MS.
Margaryan T, Sargsyan M, Gevorgyan A, Zakaryan H, Aleksanyan A, Harutyunyan A, Armoudjian Y, Mikayelyan A. Margaryan T, et al. Biomed Chromatogr. 2020 Aug;34(8):e4844. doi: 10.1002/bmc.4844. Epub 2020 Apr 23. Biomed Chromatogr. 2020. PMID: 32250456
Doxepin and nordoxepin were extracted from human plasma samples by protein precipitation with acetonitrile by using protein precipitation 96-well plates. ...The developed and validated method can be successfully used to study the bioequivalence/pharmacokinetics of doxepin …
Doxepin and nordoxepin were extracted from human plasma samples by protein precipitation with acetonitrile by using protein precipita …
Doxepin concentrations in plasma and cerebrospinal fluid.
Schomburg R, Remane D, Fassbender K, Maurer HH, Spiegel J. Schomburg R, et al. J Neural Transm (Vienna). 2011 Apr;118(4):641-5. doi: 10.1007/s00702-011-0613-x. Epub 2011 Feb 25. J Neural Transm (Vienna). 2011. PMID: 21350940

The plasma concentration of both doxepin and nordoxepin correlated significantly with the oral dosage of doxepin (doxepin: r = +0.66, p < 0.001; nordoxepin: r = +0.78, p < 0.0001; Spearman's correlation). Furthermore, we found significant correlations between

…
The plasma concentration of both doxepin and nordoxepin correlated significantly with the oral dosage of doxepin (doxepin: r = +0.66, …
Highly sensitive LC-MS/MS method to estimate doxepin and its metabolite nordoxepin in human plasma for a bioequivalence study.
Patel NP, Sanyal M, Sharma N, Patel DS, Shrivastav PS, Patel BN. Patel NP, et al. J Pharm Anal. 2018 Dec;8(6):378-385. doi: 10.1016/j.jpha.2017.06.004. Epub 2017 Jun 16. J Pharm Anal. 2018. PMID: 30595944 Free PMC article.
A selective, sensitive and rugged liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay has been developed for the simultaneous determination of doxepin (Dox) and its pharmacologically active metabolite, nordoxepin (NDox) in human plasma. The analytes and their i …
A selective, sensitive and rugged liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay has been developed for the simultaneous de …
Simultaneous liquid chromatographic analysis of amitriptyline, nortriptyline, imipramine, desipramine, doxepin, and nordoxepin.
Kabra PM, Mar NA, Marton LJ. Kabra PM, et al. Clin Chim Acta. 1981 Apr 9;111(2-3):123-32. doi: 10.1016/0009-8981(81)90179-0. Clin Chim Acta. 1981. PMID: 7226545
A simultaneous method for the therapeutic monitoring of amitriptyline, doxepin, imipramine, and their active demethylated metabolites nortriptyline, nordoxepin, and desipramine, respectively, in plasma or serum by reversed-phase liquid chromatography (RPLC) is presented. . …
A simultaneous method for the therapeutic monitoring of amitriptyline, doxepin, imipramine, and their active demethylated metabolites nortri …
Determination of carbamazepine by HPLC electrochemical detection and application for estimation of imipramine desipramine, doxepin and nordoxepin.
Messiha FS. Messiha FS. Alcohol. 1986 Mar-Apr;3(2):135-8. doi: 10.1016/0741-8329(86)90023-6. Alcohol. 1986. PMID: 3718666
The assay was also found applicable for the simultaneous separation of imipramine from desipramine or doxepin from nordoxepin. The procedure does not require the use of UV detection, is less time consuming and provides sensitivity at ng and microgram level for the tricycli …
The assay was also found applicable for the simultaneous separation of imipramine from desipramine or doxepin from nordoxepin. The pr …
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.
Kirchherr H, Kühn-Velten WN. Kirchherr H, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Oct 20;843(1):100-13. doi: 10.1016/j.jchromb.2006.05.031. Epub 2006 Jun 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16798119
This method describes the simultaneous determination of amisulpride, amitriptyline, aripiprazole, benperidol, chlorpromazine, chlorprothixene, citalopram, clomipramine, clozapine, desipramine, doxepin, fluoxetine, flupentixol, fluphenazine, fluvoxamine, haloperidol, hydroxyrisper …
This method describes the simultaneous determination of amisulpride, amitriptyline, aripiprazole, benperidol, chlorpromazine, chlorprothixen …
A fatal doxepin poisoning associated with a defective CYP2D6 genotype.
Koski A, Ojanperä I, Sistonen J, Vuori E, Sajantila A. Koski A, et al. Am J Forensic Med Pathol. 2007 Sep;28(3):259-61. doi: 10.1097/PAF.0b013e3180326701. Am J Forensic Med Pathol. 2007. PMID: 17721180
The doxepin concentration was 2.4 mg/L, the concentration of nordoxepin 2.9 mg/L, and the doxepin/nordoxepin ratio 0.83, the lowest found among the 35 nordoxepin-positive postmortem cases analyzed during the same year. ...
The doxepin concentration was 2.4 mg/L, the concentration of nordoxepin 2.9 mg/L, and the doxepin/nordoxepin ratio 0.83, the l …
30 results