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Biology of PEST-Containing Nuclear Protein: A Potential Molecular Target for Cancer Research.
Khan NH, Chen HJ, Fan Y, Surfaraz M, Ahammad MF, Qin YZ, Shahid M, Virk R, Jiang E, Wu DD, Ji XY. Khan NH, et al. Front Oncol. 2022 Feb 4;12:784597. doi: 10.3389/fonc.2022.784597. eCollection 2022. Front Oncol. 2022. PMID: 35186732 Free PMC article. Review.
PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in vital cellular processes like cell proliferation and mediates tumorigenesis. PCNP is a short-living, small nuclear protein of only 178 amino acids with
PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in vital cellular processes
Taking a holistic view of PEST-containing nuclear protein (PCNP) in cancer biology.
Afzal A, Sarfraz M, Li GL, Ji SP, Duan SF, Khan NH, Wu DD, Ji XY. Afzal A, et al. Cancer Med. 2019 Oct;8(14):6335-6343. doi: 10.1002/cam4.2465. Epub 2019 Sep 5. Cancer Med. 2019. PMID: 31487123 Free PMC article. Review.
Polypeptide sequences enriched with proline (P), glutamic acid (E), aspartic acid (D) and serine (S)/ threonine (T) (PEST) have been reported to be the most abundant and frequently distributed at the cellular level. ...A PEST containing nuclear protein
Polypeptide sequences enriched with proline (P), glutamic acid (E), aspartic acid (D) and serine (S)/ threonine (T) (PEST) have been …
Recent Insights into the Roles of PEST-Containing Nuclear Protein.
Guo S, Ding R, Zhao Q, Wang X, Lv S, Ji XY. Guo S, et al. Mol Biotechnol. 2024 May 19. doi: 10.1007/s12033-024-01188-5. Online ahead of print. Mol Biotechnol. 2024. PMID: 38762838 Review.
PEST-containing nuclear protein (PCNP), a short-lived small nuclear protein with 178 amino acids, is a nuclear protein containing two PEST sequences. ...The main relevant articles were retrieved from PubMed, with keywords su
PEST-containing nuclear protein (PCNP), a short-lived small nuclear protein with 178 amino acids, is a
PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma.
Wang DY, Hong Y, Chen YG, Dong PZ, Liu SY, Gao YR, Lu D, Li HM, Li T, Guo JC, He F, Ren XQ, Sun SY, Wu DD, Duan SF, Ji XY. Wang DY, et al. Oncogenesis. 2019 Mar 14;8(3):22. doi: 10.1038/s41389-019-0132-4. Oncogenesis. 2019. PMID: 30872582 Free PMC article.
Lung cancer is the leading cause of cancer-related mortality worldwide. PEST-containing nuclear protein (PCNP) has been found in the nucleus of cancer cells. ...
Lung cancer is the leading cause of cancer-related mortality worldwide. PEST-containing nuclear protein (PCNP) has been …
Pest sequences in nuclear proteins.
Chevaillier P. Chevaillier P. Int J Biochem. 1993 Apr;25(4):479-82. doi: 10.1016/0020-711x(93)90653-v. Int J Biochem. 1993. PMID: 8096823 Review.
This correlation was tested on nuclear proteins and a close relationship was found between nuclear protein stability and the presence of PEST regions. 3. Nuclear proteins with structural functions which can be considered as stable components of cell nuclei ge …
This correlation was tested on nuclear proteins and a close relationship was found between nuclear protein stability and the p …
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
Wu DD, Gao YR, Li T, Wang DY, Lu D, Liu SY, Hong Y, Ning HB, Liu JP, Shang J, Shi JF, Wei JS, Ji XY. Wu DD, et al. BMC Cancer. 2018 May 2;18(1):499. doi: 10.1186/s12885-018-4391-9. BMC Cancer. 2018. PMID: 29716528 Free PMC article.
BACKGROUND: PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in cell proliferation and tumorigenesis. ...
BACKGROUND: PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in cell prolifer …
Multifaceted behavior of PEST sequence enriched nuclear proteins in cancer biology and role in gene therapy.
Sarfraz M, Afzal A, Khattak S, Saddozai UAK, Li HM, Zhang QQ, Madni A, Haleem KS, Duan SF, Wu DD, Ji SP, Ji XY. Sarfraz M, et al. J Cell Physiol. 2021 Mar;236(3):1658-1676. doi: 10.1002/jcp.30011. Epub 2020 Aug 25. J Cell Physiol. 2021. PMID: 32841373 Review.
The amino acid sequence enriched with proline (P), glutamic acid (E), serine (S), and threonine (T) (PEST) is a signal-transducing agent providing unique features to its substrate nuclear proteins (PEST-NPs). The PEST motif is responsible for particular postt …
The amino acid sequence enriched with proline (P), glutamic acid (E), serine (S), and threonine (T) (PEST) is a signal-transducing ag …
NIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP, a PEST-containing nuclear protein.
Mori T, Li Y, Hata H, Kochi H. Mori T, et al. FEBS Lett. 2004 Jan 16;557(1-3):209-14. doi: 10.1016/s0014-5793(03)01495-9. FEBS Lett. 2004. PMID: 14741369 Free article.
We previously reported the association of a novel Np95/ICBP90-like RING finger protein (NIRF) with a novel PEST-containing nuclear protein (PCNP). NIRF is a nuclear protein with a ubiquitin-like domain, a PHD finger, a YDG/SRA domain, Rb-binding …
We previously reported the association of a novel Np95/ICBP90-like RING finger protein (NIRF) with a novel PEST-containing nuclear
NODULIN HOMEOBOX is required for heterochromatin homeostasis in Arabidopsis.
Karányi Z, Mosolygó-L Á, Feró O, Horváth A, Boros-Oláh B, Nagy É, Hetey S, Holb I, Szaker HM, Miskei M, Csorba T, Székvölgyi L. Karányi Z, et al. Nat Commun. 2022 Aug 27;13(1):5058. doi: 10.1038/s41467-022-32709-y. Nat Commun. 2022. PMID: 36030240 Free PMC article.
Arabidopsis NODULIN HOMEOBOX (NDX) is a nuclear protein described as a regulator of specific euchromatic genes within transcriptionally active chromosome arms. ...
Arabidopsis NODULIN HOMEOBOX (NDX) is a nuclear protein described as a regulator of specific euchromatic genes within transcri …
30 results