Multifaceted behavior of PEST sequence enriched nuclear proteins in cancer biology and role in gene therapy.
Sarfraz M, Afzal A, Khattak S, Saddozai UAK, Li HM, Zhang QQ, Madni A, Haleem KS, Duan SF, Wu DD, Ji SP, Ji XY.
Sarfraz M, et al.
J Cell Physiol. 2021 Mar;236(3):1658-1676. doi: 10.1002/jcp.30011. Epub 2020 Aug 25.
J Cell Physiol. 2021.
PMID: 32841373
Review.
The amino acid sequence enriched with proline (P), glutamic acid (E), serine (S), and threonine (T) (PEST) is a signal-transducing agent providing unique features to its substrate nuclear proteins (PEST-NPs). The PEST motif is responsible for particular postt …
The amino acid sequence enriched with proline (P), glutamic acid (E), serine (S), and threonine (T) (PEST) is a signal-transducing ag …