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Omacor (prescription omega-3-acid ethyl esters 90): From severe rhythm disorders to hypertriglyceridemia.
Rupp H. Rupp H. Adv Ther. 2009 Jul;26(7):675-90. doi: 10.1007/s12325-009-0045-2. Epub 2009 Jul 27. Adv Ther. 2009. PMID: 19629408 Review.
To avoid further confusion, guidelines should be precise and refer to the medication, eg, as in NICE guideline CG48: "Omega-3-acid ethyl esters treatment licensed for secondary prevention post-MI." ...
To avoid further confusion, guidelines should be precise and refer to the medication, eg, as in NICE guideline CG48: "Omega-3- …
Differentiating prescription omega-3-acid ethyl esters (P-OM3) from dietary-supplement omega-3 fatty acids.
Brunton S, Collins N. Brunton S, et al. Curr Med Res Opin. 2007 May;23(5):1139-45. doi: 10.1185/030079907x188017. Curr Med Res Opin. 2007. PMID: 17519081 Review.
OBJECTIVES: This article is intended to review clinically relevant differences between dietary-supplement omega-3 fatty acids and prescription omega-3-acid ethyl esters (P-OM3). METHODS: PubMed and the Food and Drug Administration (FDA) Website …
OBJECTIVES: This article is intended to review clinically relevant differences between dietary-supplement omega-3 fatty acids and prescripti …
Omega-3 polyunsaturated fatty acids and cardiovascular disease: an emphasis on omega-3-acid ethyl esters 90 for the treatment of hypertriglyceridemia.
Tatsuno I. Tatsuno I. Expert Rev Cardiovasc Ther. 2014 Nov;12(11):1261-8. doi: 10.1586/14779072.2014.971756. Epub 2014 Oct 16. Expert Rev Cardiovasc Ther. 2014. PMID: 25319059 Review.
Currently, omega-3 fatty acids are commercially available in many parts of the world containing the same active ingredients as Lotriga() (omega-3-acid ethyl esters 90 [O3AE highly concentrated omega-3 fatty acid ethyl esters, consisting of eicos …
Currently, omega-3 fatty acids are commercially available in many parts of the world containing the same active ingredients as Lotriga() ( …
Prescription omega-3-acid ethyl esters for the treatment of very high triglycerides.
Sadovsky R, Kris-Etherton P. Sadovsky R, et al. Postgrad Med. 2009 Jul;121(4):145-53. doi: 10.3810/pgm.2009.07.2020. Postgrad Med. 2009. PMID: 19641280 Review.
Data show that intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can significantly decrease serum TGs, along with plasma concentrations of certain lipoproteins. Omega-3-acid ethyl esters are available by prescription or as die …
Data show that intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can significantly decrease serum TGs, along with plasma …
Effect of omega-3 ethyl esters on the triglyceride-rich lipoprotein response to endotoxin challenge in healthy young men.
Walker RE, Richter CK, Skulas-Ray AC, Flock MR, Harsch BA, Annevelink CE, Kris-Etherton PM, Jensen GL, Shearer GC. Walker RE, et al. J Lipid Res. 2023 May;64(5):100353. doi: 10.1016/j.jlr.2023.100353. Epub 2023 Mar 11. J Lipid Res. 2023. PMID: 36907552 Free PMC article. Clinical Trial.
Inflammation elevates TGRL concentrations, but it is unknown if the fatty acid and oxylipin compositions change. In this study, we investigated the effect of prescription omega-3 acid ethyl esters (P-OM3; 3.4 g/d EPA + DHA) on the lipid response …
Inflammation elevates TGRL concentrations, but it is unknown if the fatty acid and oxylipin compositions change. In this study, we investiga …
Prescription omega-3 fatty acid products: considerations for patients with diabetes mellitus.
Tajuddin N, Shaikh A, Hassan A. Tajuddin N, et al. Diabetes Metab Syndr Obes. 2016 Apr 19;9:109-18. doi: 10.2147/DMSO.S97036. eCollection 2016. Diabetes Metab Syndr Obes. 2016. PMID: 27143943 Free PMC article. Review.
Prescription OM3FAs contain either combinations of DHA and EPA (omega-3-acid ethyl esters, omega-3-carboxylic acids, omega-3-acid ethyl esters A) or EPA alone (icosapent ethyl). ...
Prescription OM3FAs contain either combinations of DHA and EPA (omega-3-acid ethyl esters, omega-3-carbox …
Bioequivalence Demonstration for Ω-3 Acid Ethyl Ester Formulations: Rationale for Modification of Current Guidance.
Maki KC, Johns C, Harris WS, Puder M, Freedman SD, Thorsteinsson T, Daak A, Rabinowicz AL, Sancilio FD. Maki KC, et al. Clin Ther. 2017 Mar;39(3):652-658. doi: 10.1016/j.clinthera.2017.01.019. Epub 2017 Feb 8. Clin Ther. 2017. PMID: 28189365
This article presents an argument for amending the FDA draft guidance for omega-3 acid ethyl esters to use baseline-adjusted EPA and DHA in total plasma lipids as the primary measures of BE for both fasting and fed conditions. This change would …
This article presents an argument for amending the FDA draft guidance for omega-3 acid ethyl esters to us …
Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial Infarction: The OMEGA-REMODEL Randomized Clinical Trial.
Heydari B, Abdullah S, Pottala JV, Shah R, Abbasi S, Mandry D, Francis SA, Lumish H, Ghoshhajra BB, Hoffmann U, Appelbaum E, Feng JH, Blankstein R, Steigner M, McConnell JP, Harris W, Antman EM, Jerosch-Herold M, Kwong RY. Heydari B, et al. Circulation. 2016 Aug 2;134(5):378-91. doi: 10.1161/CIRCULATIONAHA.115.019949. Circulation. 2016. PMID: 27482002 Free PMC article. Clinical Trial.
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