MPS VI associated ocular phenotypes in an MPS VI murine model and the therapeutic effects of odiparcil treatment.
Entchev E, Antonelli S, Mauro V, Cimbolini N, Jantzen I, Roussey A, Germain JM, Zhang H, Luccarrini JM, Lacombe O, Young SP, Feraille L, Tallandier M.
Entchev E, et al.
Mol Genet Metab. 2022 Feb;135(2):143-153. doi: 10.1016/j.ymgme.2021.07.008. Epub 2021 Jul 25.
Mol Genet Metab. 2022.
PMID: 34417096
Free article.
Histological examination of MPS VI Arsb(-) eyes showed an aggregate of corneal phenotypes, including reduction in the corneal epithelium thickness and number of epithelial cell layers, and morphological malformations in the stroma. ...Orally administered odip …
Histological examination of MPS VI Arsb(-) eyes showed an aggregate of corneal phenotypes, including reduction in the corneal …