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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
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1985 1
1986 1
1990 1
1994 1
1995 1
1997 1
1998 1
2000 1
2001 2
2002 3
2004 1
2006 2
2007 1
2008 1
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2011 2
2012 2
2013 1
2014 2
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2018 1
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2023 1
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38 results

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Page 1
Optic nerve hypoplasia: changing perspectives.
Hoyt CS, Billson FA. Hoyt CS, et al. Aust N Z J Ophthalmol. 1986 Nov;14(4):325-31. doi: 10.1111/j.1442-9071.1986.tb00467.x. Aust N Z J Ophthalmol. 1986. PMID: 3545264 Review.
Optic nerve hypoplasia, having once been regarded as exceedingly rare, is now regarded as one of the major causes of visual loss in infancy. ...These changing clinical perspectives are reviewed, together with a discussion of the pathogenesis of opti …
Optic nerve hypoplasia, having once been regarded as exceedingly rare, is now regarded as one of the major causes of vi …
Maternal anticonvulsants and optic nerve hypoplasia.
Hoyt CS, Billson FA. Hoyt CS, et al. Br J Ophthalmol. 1978 Jan;62(1):3-6. doi: 10.1136/bjo.62.1.3. Br J Ophthalmol. 1978. PMID: 415754 Free PMC article.
Seven patients with optic nerve hypoplasia, born of epileptic mothers, are presented. ...The possibility that maternal anticonvulsant therapy may play a role in the genesis of optic nerve hypoplasia is discussed in the light of what is kn …
Seven patients with optic nerve hypoplasia, born of epileptic mothers, are presented. ...The possibility that maternal …
Optic nerve hypoplasia: comparative effects in children and rats exposed to alcohol during pregnancy.
Strömland K, Pinazo-Durán MD. Strömland K, et al. Teratology. 1994 Aug;50(2):100-11. doi: 10.1002/tera.1420500204. Teratology. 1994. PMID: 7801297 Clinical Trial.
These include abnormalities of the eyes and adnexa (strabismus, blepharoptosis, epicanthus), as well as intraocular defects (cataract, glaucoma, persistent hyperplastic primary vitreous, retinal and optic nerve anomalies). Based on the clinical results in an ophthalmologic …
These include abnormalities of the eyes and adnexa (strabismus, blepharoptosis, epicanthus), as well as intraocular defects (cataract, glauc …
Optic nerve hypoplasia in fetal alcohol syndrome: an update.
Pinazo-Duran MD, Renau-Piqueras J, Guerri C, Strömland K. Pinazo-Duran MD, et al. Eur J Ophthalmol. 1997 Jul-Sep;7(3):262-70. doi: 10.1177/112067219700700311. Eur J Ophthalmol. 1997. PMID: 9352281
Optic nerve hypoplasia was detected in up to one half of a group of Swedish children born to alcoholic mothers. ...
Optic nerve hypoplasia was detected in up to one half of a group of Swedish children born to alcoholic mothers. ...
Ocular involvement in fetal alcohol spectrum disorder: a review.
Brennan D, Giles S. Brennan D, et al. Curr Pharm Des. 2014;20(34):5377-87. doi: 10.2174/1381612820666140205144114. Curr Pharm Des. 2014. PMID: 24502600 Review.
Although ethanol can affect many of the major systems of the body, the eye is a primary target. Ocular aberrations including optic nerve hypoplasia, tortuosity of retinal vessels, coloboma and microphthalmia are frequently observed in children diagnosed with …
Although ethanol can affect many of the major systems of the body, the eye is a primary target. Ocular aberrations including optic …
Optic nerve hypoplasia.
Zion V. Zion V. Ophthalmic Semin. 1976;1(2):171-96. Ophthalmic Semin. 1976. PMID: 799278 Review. No abstract available.
Clinical assessment, optic disk measurements, and visual-evoked potential in optic nerve hypoplasia.
Borchert M, McCulloch D, Rother C, Stout AU. Borchert M, et al. Am J Ophthalmol. 1995 Nov;120(5):605-12. doi: 10.1016/s0002-9394(14)72207-x. Am J Ophthalmol. 1995. PMID: 7485362
METHODS: We prospectively studied the eyes of 19 children (eight consecutive and 11 randomly selected), ages 7 to 92 months, in whom a diagnosis of optic nerve hypoplasia was made by an ophthalmologist. ...CONCLUSIONS: Visual-evoked potential and photo …
METHODS: We prospectively studied the eyes of 19 children (eight consecutive and 11 randomly selected), ages 7 to 92 months, in whom …
Onset of pituitary hormone deficiencies in optic nerve hypoplasia: a temporal trend analysis of 32 children at Mayo Clinic.
Wadams HD, Gupta N, Novotny P, Tebben PJ. Wadams HD, et al. J Pediatr Endocrinol Metab. 2020 Jan 28;33(1):139-145. doi: 10.1515/jpem-2019-0269. J Pediatr Endocrinol Metab. 2020. PMID: 31811804 Clinical Trial.
Background The objective of this study was to evaluate the age at onset and frequency of individual pituitary hormone deficiencies (PHDs) in optic nerve hypoplasia (ONH). Methods We performed a retrospective chart review of patients 21 years of age evaluated …
Background The objective of this study was to evaluate the age at onset and frequency of individual pituitary hormone deficiencies (PHDs) in …
Aberrant gene expression yet undiminished retinal ganglion cell genesis in iPSC-derived models of optic nerve hypoplasia.
Aparicio JG, Hopp H, Harutyunyan N, Stewart C, Cobrinik D, Borchert M. Aparicio JG, et al. Ophthalmic Genet. 2024 Feb;45(1):1-15. doi: 10.1080/13816810.2023.2253902. Epub 2024 Jan 26. Ophthalmic Genet. 2024. PMID: 37807874
BACKGROUND: Optic nerve hypoplasia (ONH), the leading congenital cause of permanent blindness, is characterized by a retinal ganglion cell (RGC) deficit at birth. ...Differential expression of 70 genes was identified in both DESeq2 and edgeR analyses, represe …
BACKGROUND: Optic nerve hypoplasia (ONH), the leading congenital cause of permanent blindness, is characterized by a re …
38 results