Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child.
Bromley R, Adab N, Bluett-Duncan M, Clayton-Smith J, Christensen J, Edwards K, Greenhalgh J, Hill RA, Jackson CF, Khanom S, McGinty RN, Tudur Smith C, Pulman J, Marson AG.
Bromley R, et al.
Cochrane Database Syst Rev. 2023 Aug 29;8(8):CD010224. doi: 10.1002/14651858.CD010224.pub3.
Cochrane Database Syst Rev. 2023.
PMID: 37647086
Free PMC article.
Review.
Risk ratios were significantly higher for children exposed to topiramate in comparison to the children of women without epilepsy in cohort studies (RR 4.07, 95% CI 1.64 to 10.14) but not in a smaller comparison to the children of women with untreated epilepsy (RR 1.37, 95% …
Risk ratios were significantly higher for children exposed to topiramate in comparison to the children of women without epilepsy in cohort s …