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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1983 5
1984 5
1985 6
1986 3
1987 1
1988 8
1989 4
1990 3
1991 2
1992 3
1993 9
1994 10
1995 13
1996 9
1997 10
1998 12
1999 10
2000 12
2001 15
2002 10
2003 20
2004 25
2005 32
2006 28
2007 36
2008 33
2009 31
2010 52
2011 64
2012 74
2013 107
2014 117
2015 162
2016 191
2017 205
2018 217
2019 235
2020 233
2021 225
2022 254
2023 260
2024 72

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2,405 results

Results by year

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Page 1
Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial.
Yannopoulos D, Bartos J, Raveendran G, Walser E, Connett J, Murray TA, Collins G, Zhang L, Kalra R, Kosmopoulos M, John R, Shaffer A, Frascone RJ, Wesley K, Conterato M, Biros M, Tolar J, Aufderheide TP. Yannopoulos D, et al. Lancet. 2020 Dec 5;396(10265):1807-1816. doi: 10.1016/S0140-6736(20)32338-2. Epub 2020 Nov 13. Lancet. 2020. PMID: 33197396 Free PMC article. Clinical Trial.
BACKGROUND: Among patients with out-of-hospital cardiac arrest (OHCA) and ventricular fibrillation, more than half present with refractory ventricular fibrillation unresponsive to initial standard advanced cardiac life support (ACLS) treatment. …
BACKGROUND: Among patients with out-of-hospital cardiac arrest (OHCA) and ventricular fibrillation, more …
Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.
Belohlavek J, Smalcova J, Rob D, Franek O, Smid O, Pokorna M, Horák J, Mrazek V, Kovarnik T, Zemanek D, Kral A, Havranek S, Kavalkova P, Kompelentova L, Tomková H, Mejstrik A, Valasek J, Peran D, Pekara J, Rulisek J, Balik M, Huptych M, Jarkovsky J, Malik J, Valerianova A, Mlejnsky F, Kolouch P, Havrankova P, Romportl D, Komarek A, Linhart A; Prague OHCA Study Group. Belohlavek J, et al. JAMA. 2022 Feb 22;327(8):737-747. doi: 10.1001/jama.2022.1025. JAMA. 2022. PMID: 35191923 Free PMC article. Clinical Trial.
IMPORTANCE: Out-of-hospital cardiac arrest (OHCA) has poor outcome. Whether intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and immediate invasive assessment and treatment (invasive strategy) is beneficial in this se …
IMPORTANCE: Out-of-hospital cardiac arrest (OHCA) has poor outcome. Whether intra-arrest transport, extra …
Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest.
François B, Cariou A, Clere-Jehl R, Dequin PF, Renon-Carron F, Daix T, Guitton C, Deye N, Legriel S, Plantefève G, Quenot JP, Desachy A, Kamel T, Bedon-Carte S, Diehl JL, Chudeau N, Karam E, Durand-Zaleski I, Giraudeau B, Vignon P, Le Gouge A; CRICS-TRIGGERSEP Network and the ANTHARTIC Study Group. François B, et al. N Engl J Med. 2019 Nov 7;381(19):1831-1842. doi: 10.1056/NEJMoa1812379. N Engl J Med. 2019. PMID: 31693806 Clinical Trial.
BACKGROUND: Patients who are treated with targeted temperature management after out-of-hospital cardiac arrest with shockable rhythm are at increased risk for ventilator-associated pneumonia. The benefit of preventive short-term antibiotic thera …
BACKGROUND: Patients who are treated with targeted temperature management after out-of-hospital cardiac arres …
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, Leroux B, Vaillancourt C, Wittwer L, Callaway CW, Christenson J, Egan D, Ornato JP, Weisfeldt ML, Stiell IG, Idris AH, Aufderheide TP, Dunford JV, Colella MR, Vilke GM, Brienza AM, Desvigne-Nickens P, Gray PC, Gray R, Seals N, Straight R, Dorian P; Resuscitation Outcomes Consortium Investigators. Kudenchuk PJ, et al. N Engl J Med. 2016 May 5;374(18):1711-22. doi: 10.1056/NEJMoa1514204. Epub 2016 Apr 4. N Engl J Med. 2016. PMID: 27043165 Free article. Clinical Trial.
BACKGROUND: Antiarrhythmic drugs are used commonly in out-of-hospital cardiac arrest for shock-refractory ventricular fibrillation or pulseless ventricular tachycardia, but without proven survival benefit. METHODS: In this randomized, dou …
BACKGROUND: Antiarrhythmic drugs are used commonly in out-of-hospital cardiac arrest for shock-refractory …
Mechanical chest compression with LUCAS device does not improve clinical outcome in out-of-hospital cardiac arrest patients: A systematic review and meta-analysis.
Liu M, Shuai Z, Ai J, Tang K, Liu H, Zheng J, Gou J, Lv Z. Liu M, et al. Medicine (Baltimore). 2019 Nov;98(44):e17550. doi: 10.1097/MD.0000000000017550. Medicine (Baltimore). 2019. PMID: 31689757 Free PMC article.
RESULTS: A total of 6 articles, including 4 randomized controlled trials and 2 nonrandomized controlled trials, were selected. And 8501 subjects were involved to analyze the clinical outcomes of LUCAS and manual chest compression for patients with out-hospital CA. . …
RESULTS: A total of 6 articles, including 4 randomized controlled trials and 2 nonrandomized controlled trials, were selected. And 85 …
Safety of mechanical and manual chest compressions in cardiac arrest patients: A systematic review and meta-analysis.
Gao Y, Sun T, Yuan D, Liang H, Wan Y, Yuan B, Zhu C, Li Y, Yu Y. Gao Y, et al. Resuscitation. 2021 Dec;169:124-135. doi: 10.1016/j.resuscitation.2021.10.028. Epub 2021 Oct 24. Resuscitation. 2021. PMID: 34699924 Free article. Review.
METHODS: Two investigators separately screened the articles of EMBASE, PubMed, and Cochrane Central databases. Cohort studies and randomized clinical trials (RCTs) that evaluated the safety of mechanical (LUCAS or AutoPulse) and manual chest compressions in cardiac …
METHODS: Two investigators separately screened the articles of EMBASE, PubMed, and Cochrane Central databases. Cohort studies and randomi …
Low-dose colchicine for secondary prevention of cardiovascular disease.
Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL. Nidorf SM, et al. J Am Coll Cardiol. 2013 Jan 29;61(4):404-410. doi: 10.1016/j.jacc.2012.10.027. Epub 2012 Dec 19. J Am Coll Cardiol. 2013. PMID: 23265346 Free article. Clinical Trial.
BACKGROUND: The presence of activated neutrophils in culprit atherosclerotic plaques of patients with unstable coronary disease raises the possibility that inhibition of neutrophil function with colchicine may reduce the risk of plaque instability and thereby improve clinical …
BACKGROUND: The presence of activated neutrophils in culprit atherosclerotic plaques of patients with unstable coronary disease raises the p …
Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial.
Le May M, Osborne C, Russo J, So D, Chong AY, Dick A, Froeschl M, Glover C, Hibbert B, Marquis JF, De Roock S, Labinaz M, Bernick J, Marshall S, Maze R, Wells G. Le May M, et al. JAMA. 2021 Oct 19;326(15):1494-1503. doi: 10.1001/jama.2021.15703. JAMA. 2021. PMID: 34665203 Free PMC article. Clinical Trial.
IMPORTANCE: Comatose survivors of out-of-hospital cardiac arrest experience high rates of death and severe neurologic injury. ...OBJECTIVE: To determine whether moderate hypothermia (31 C), compared with mild hypothermia (34 C), improves clin …
IMPORTANCE: Comatose survivors of out-of-hospital cardiac arrest experience high rates of death and sever …
Temperature Management for Comatose Adult Survivors of Cardiac Arrest: A Science Advisory From the American Heart Association.
Perman SM, Bartos JA, Del Rios M, Donnino MW, Hirsch KG, Jentzer JC, Kudenchuk PJ, Kurz MC, Maciel CB, Menon V, Panchal AR, Rittenberger JC, Berg KM; American Heart Association Emergency Cardiovascular Care Committee, Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Peripheral Vascular Disease; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation, and Stroke Council. Perman SM, et al. Circulation. 2023 Sep 19;148(12):982-988. doi: 10.1161/CIR.0000000000001164. Epub 2023 Aug 16. Circulation. 2023. PMID: 37584195 Review.
The suggested temperature range expanded in 2015 in response to a large trial finding that outcomes were not better with treatment at 33 C compared with 36 C. ...To provide guidance to clinicians while this focused update is forthcoming, the American Heart Association's Em …
The suggested temperature range expanded in 2015 in response to a large trial finding that outcomes were not better with treatment at …
Survival by time-to-administration of amiodarone, lidocaine, or placebo in shock-refractory out-of-hospital cardiac arrest.
Lupton JR, Neth MR, Sahni R, Jui J, Wittwer L, Newgard CD, Daya MR. Lupton JR, et al. Acad Emerg Med. 2023 Sep;30(9):906-917. doi: 10.1111/acem.14716. Epub 2023 Apr 5. Acad Emerg Med. 2023. PMID: 36869657 Clinical Trial.
BACKGROUND: Amiodarone and lidocaine have not been shown to have a clear survival benefit compared to placebo for out-of-hospital cardiac arrest (OHCA). However, randomized trials may have been impacted by delayed administration of the st …
BACKGROUND: Amiodarone and lidocaine have not been shown to have a clear survival benefit compared to placebo for out-of-ho …
2,405 results