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Page 1
Myometrial Responses to Beta-Adrenoceptor Antagonists in Gynecological Malignancies.
Modzelewska B, Jóźwik M, Kleszczewski T, Sulkowski S, Jóźwik M. Modzelewska B, et al. Gynecol Obstet Invest. 2021;86(1-2):162-169. doi: 10.1159/000513718. Epub 2021 Feb 26. Gynecol Obstet Invest. 2021. PMID: 33640886

RESULTS: Propranolol and bupranolol attenuated contractions in the endometrial and cervical cancer groups similar to that in the reference group (all p < 0.05), whereas opposite effects were observed in the ovarian and synchronous ovarian-endometrial ca

RESULTS: Propranolol and bupranolol attenuated contractions in the endometrial and cervical cancer groups similar to that in the reference g …
Aromatase inhibitors: possible future applications.
Karaer O, Oruç S, Koyuncu FM. Karaer O, et al. Acta Obstet Gynecol Scand. 2004 Aug;83(8):699-706. doi: 10.1111/j.0001-6349.2004.00562.x. Acta Obstet Gynecol Scand. 2004. PMID: 15255840 Free article. Review.
The use of AIs in gynecomastia, puberte precox, leiomyoma uteri, some estrogen-dependent cancers (ovarian), endometrial cancer and male infertility are reported; some of the results are promising but more clinical trials are needed. AIs are predicted t …
The use of AIs in gynecomastia, puberte precox, leiomyoma uteri, some estrogen-dependent cancers (ovarian), endometrial can
Circulating estrogens and postmenopausal ovarian and endometrial cancer risk among current hormone users in the Women's Health Initiative Observational Study.
Trabert B, Coburn SB, Falk RT, Manson JE, Brinton LA, Gass ML, Kuller LH, Rohan TE, Pfeiffer RM, Qi L, Stefanick ML, Wentzensen N, Anderson GL, Xu X. Trabert B, et al. Cancer Causes Control. 2019 Nov;30(11):1201-1211. doi: 10.1007/s10552-019-01233-8. Epub 2019 Sep 21. Cancer Causes Control. 2019. PMID: 31542834 Free PMC article.
METHODS: We conducted a nested case-control study among postmenopausal women using MHT at baseline in the Women's Health Initiative Observational Study (179 ovarian cancers, 396 controls; 230 endometrial cancers, 253 controls). ...Larger studies are needed to delineate the …
METHODS: We conducted a nested case-control study among postmenopausal women using MHT at baseline in the Women's Health Initiative Obser
Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.
Ramus SJ, Elmasry K, Luo Z, Gammerman A, Lu K, Ayhan A, Singh N, McCluggage WG, Jacobs IJ, Whittaker JC, Gayther SA. Ramus SJ, et al. Clin Cancer Res. 2008 Sep 15;14(18):5840-8. doi: 10.1158/1078-0432.CCR-08-0373. Clin Cancer Res. 2008. PMID: 18794095
CONCLUSIONS: Genetic analysis may represent a powerful tool for use in clinical practice for distinguishing between SPM and DP in patients with synchronous ovarian/endometrial cancer and predicting disease outcome. The data also suggest a hitherto unch …
CONCLUSIONS: Genetic analysis may represent a powerful tool for use in clinical practice for distinguishing between SPM and DP in patients w …
Altered uterine contractility in response to β-adrenoceptor agonists in ovarian cancer.
Modzelewska B, Jóźwik M, Jóźwik M, Sulkowski S, Pędzińska-Betiuk A, Kleszczewski T, Kostrzewska A. Modzelewska B, et al. J Physiol Sci. 2017 Nov;67(6):711-722. doi: 10.1007/s12576-016-0500-1. Epub 2016 Nov 12. J Physiol Sci. 2017. PMID: 27838886 Free PMC article.
All agonists induced a dose-dependent attenuation for uterine contractility in endometrial or cervical cancer, similar to that observed in the reference group. Contradictory effects were observed for ovarian cancer alone or in combination with endometrial cancer. .. …
All agonists induced a dose-dependent attenuation for uterine contractility in endometrial or cervical cancer, similar to that observed
Alcohol and oestrogen metabolites in postmenopausal women in the Women's Health Initiative Observational Study.
Playdon MC, Coburn SB, Moore SC, Brinton LA, Wentzensen N, Anderson G, Wallace R, Falk RT, Pfeiffer R, Xu X, Trabert B. Playdon MC, et al. Br J Cancer. 2018 Feb 6;118(3):448-457. doi: 10.1038/bjc.2017.419. Epub 2017 Dec 12. Br J Cancer. 2018. PMID: 29235567 Free PMC article.
We examined associations of alcohol consumption with circulating oestrogen/oestrogen metabolites in postmenopausal women in the Women's Health Initiative (WHI)-Observational Study (OS). METHODS: We conducted a cross-sectional analysis of prediagnosis ovarian/endo
We examined associations of alcohol consumption with circulating oestrogen/oestrogen metabolites in postmenopausal women in the Women's Heal …