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133 results

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Page 1
Sickle Cell Disease and Stroke.
Hirtz D, Kirkham FJ. Hirtz D, et al. Pediatr Neurol. 2019 Jun;95:34-41. doi: 10.1016/j.pediatrneurol.2019.02.018. Epub 2019 Feb 27. Pediatr Neurol. 2019. PMID: 30948147 Review.
Cerebral infarction is a common complication of sickle cell disease and may manifest as overt stroke or cognitive impairment associated with "silent" cerebral infarction on magnetic resonance imaging. ...Regular blood transfusion reduces, but does not abolish, the r …
Cerebral infarction is a common complication of sickle cell disease and may manifest as overt stroke or cognitive impairment a …
Dementia and Atrial Fibrillation: Pathophysiological Mechanisms and Therapeutic Implications.
Chopard R, Piazza G, Gale SA, Campia U, Albertsen IE, Kim J, Goldhaber SZ. Chopard R, et al. Am J Med. 2018 Dec;131(12):1408-1417. doi: 10.1016/j.amjmed.2018.06.035. Epub 2018 Aug 1. Am J Med. 2018. PMID: 30076825 Review.
However, atrial fibrillation has been associated with cognitive impairment and dementia, even in patients without prior overt stroke. Nonischemic mechanisms include cerebral hypoperfusion, vascular inflammation, brain atrophy, genetic factors, and shared risk factor …
However, atrial fibrillation has been associated with cognitive impairment and dementia, even in patients without prior overt stro …
Sickle cell disease.
Buchanan GR, DeBaun MR, Quinn CT, Steinberg MH. Buchanan GR, et al. Hematology Am Soc Hematol Educ Program. 2004:35-47. doi: 10.1182/asheducation-2004.1.35. Hematology Am Soc Hematol Educ Program. 2004. PMID: 15561675 Review.
Michael DeBaun characterizes the problem of silent stroke in sickle cell disease, comparing and contrasting its clinical and neuroimaging features with overt stroke. Combined, these events affect virtually 40% of children with sickle cell anemia. ...
Michael DeBaun characterizes the problem of silent stroke in sickle cell disease, comparing and contrasting its clinical and neuroimaging fe …
Neuroprotective measures throughout the TAVI pathway.
Shiyovich A, Kornowski R. Shiyovich A, et al. Minerva Cardioangiol. 2019 Feb;67(1):39-56. doi: 10.23736/S0026-4725.18.04763-1. Epub 2018 Jul 17. Minerva Cardioangiol. 2019. PMID: 30014679 Review.
However, periprocedural stroke is one of the most feared complications of TAVI, and when clinically evident, it is often associated with significant increase in mortality, physical disability, social isolation and financial costs. Furthermore, even when clinically overt …
However, periprocedural stroke is one of the most feared complications of TAVI, and when clinically evident, it is often associated with sig …
The Development of Neuroimaging Biomarkers for Cognitive Decline in Sickle Cell Disease.
Ramos K, Guilliams KP, Fields ME. Ramos K, et al. Hematol Oncol Clin North Am. 2022 Dec;36(6):1167-1186. doi: 10.1016/j.hoc.2022.07.011. Hematol Oncol Clin North Am. 2022. PMID: 36400537 Free PMC article. Review.
Sickle cell disease (SCD) is complicated by neurologic complications including vasculopathy, hemorrhagic or ischemic overt stroke, silent cerebral infarcts and cognitive dysfunction. ...
Sickle cell disease (SCD) is complicated by neurologic complications including vasculopathy, hemorrhagic or ischemic overt stroke …
Mechanisms, Clinical Significance, and Prevention of Cognitive Impairment in Patients With Atrial Fibrillation.
Rivard L, Khairy P. Rivard L, et al. Can J Cardiol. 2017 Dec;33(12):1556-1564. doi: 10.1016/j.cjca.2017.09.024. Epub 2017 Oct 6. Can J Cardiol. 2017. PMID: 29173598 Review.
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in Atrial Fibrillation (BRAIN-AF) trial is currently assessing whether oral anticoagulation can prevent cognitive decline in patients at low risk of overt stroke. Co …
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in Atrial Fibrillation (BRAIN-AF) trial …
Vascular cognitive impairment: epidemiology, subtypes, diagnosis and management.
Black SE. Black SE. J R Coll Physicians Edinb. 2011 Mar;41(1):49-56. doi: 10.4997/JRCPE.2011.121. J R Coll Physicians Edinb. 2011. PMID: 21365068 Review.
Best practice guidelines advocate screening for cognitive impairment in all phases of overt stroke, when covert CVD is uncovered, when vascular risk factors are present and if patients present with cognitive complaints. ...
Best practice guidelines advocate screening for cognitive impairment in all phases of overt stroke, when covert CVD is uncover …
Silent brain infarcts: a systematic review.
Vermeer SE, Longstreth WT Jr, Koudstaal PJ. Vermeer SE, et al. Lancet Neurol. 2007 Jul;6(7):611-9. doi: 10.1016/S1474-4422(07)70170-9. Lancet Neurol. 2007. PMID: 17582361 Review.
Most infarcts are lacunes, of which hypertensive small-vessel disease is thought to be the main cause. Although silent infarcts, by definition, lack clinically overt stroke-like symptoms, they are associated with subtle deficits in physical and cognitive function th …
Most infarcts are lacunes, of which hypertensive small-vessel disease is thought to be the main cause. Although silent infarcts, by definiti …
Burden of central nervous system complications in sickle cell disease: A systematic review and meta-analysis.
Lee S, Lucas S, Proudman D, Nellesen D, Paulose J, Sheehan VA. Lee S, et al. Pediatr Blood Cancer. 2022 Apr;69(4):e29493. doi: 10.1002/pbc.29493. Epub 2022 Jan 17. Pediatr Blood Cancer. 2022. PMID: 35038214 Review.

A meta-analysis was conducted, finding full-scale intelligence quotient (IQ) was significantly lower in: overt stroke versus controls: -12.6 (p < .001); silent cerebral infarct (SCI) versus controls: -5.7 (p < .001); overt stroke versus SCI: -9.4

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A meta-analysis was conducted, finding full-scale intelligence quotient (IQ) was significantly lower in: overt stroke versus c …
Silent brain infarction--a review of recent observations.
Kovács KR, Czuriga D, Bereczki D, Bornstein NM, Csiba L. Kovács KR, et al. Int J Stroke. 2013 Jul;8(5):334-47. doi: 10.1111/j.1747-4949.2012.00851.x. Epub 2012 Aug 1. Int J Stroke. 2013. PMID: 22863197 Review.
Accordingly, some consider silent brain infarction the preclinical stage of clinically overt stroke. This point of view emphasizes the early recognition and management of silent brain infarction-related risk factors, and a great need for comparative studies, which c …
Accordingly, some consider silent brain infarction the preclinical stage of clinically overt stroke. This point of view emphas …
133 results