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Palifermin.
[No authors listed] [No authors listed] 2020 Dec 21. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2020 Dec 21. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 33355738 Free Books & Documents. Review.
No information is available on the clinical use of palifermin during breastfeeding. Because palifermin is a large protein molecule with a molecular weight of 16,300 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably des …
No information is available on the clinical use of palifermin during breastfeeding. Because palifermin is a large protein mole …
A meta-analysis of palifermin efficacy for the management of oral mucositis in patients with solid tumours and haematological malignancy.
Coutsouvelis J, Corallo C, Spencer A, Avery S, Dooley M, Kirkpatrick CM. Coutsouvelis J, et al. Crit Rev Oncol Hematol. 2022 Apr;172:103606. doi: 10.1016/j.critrevonc.2022.103606. Epub 2022 Jan 31. Crit Rev Oncol Hematol. 2022. PMID: 35101586 Review.
A meta-analysis included randomised controlled trials (RCT) for palifermin compared to placebo or no palifermin, with the key data extracted being number of events of severe mucositis (defined by WHO criteria grade 3 or 4). ...CONCLUSION: Palifermin reduces t …
A meta-analysis included randomised controlled trials (RCT) for palifermin compared to placebo or no palifermin, with the key …
Palifermin: role in the prevention of chemotherapy- and radiation-induced mucositis.
McDonnell AM, Lenz KL. McDonnell AM, et al. Ann Pharmacother. 2007 Jan;41(1):86-94. doi: 10.1345/aph.1G473. Epub 2006 Dec 26. Ann Pharmacother. 2007. PMID: 17190850 Review.
OBJECTIVE: To assess the efficacy, toxicity, and potential cost benefit of palifermin in the prevention of chemotherapy- and radiation-induced mucositis. ...CONCLUSIONS: Treatment with palifermin appears to decrease the severity and duration of severe mucositis foll …
OBJECTIVE: To assess the efficacy, toxicity, and potential cost benefit of palifermin in the prevention of chemotherapy- and radiatio …
Palifermin: AMJ 9701, KGF-Amgen, recombinant human keratinocyte growth factor, rHu-KGF.
[No authors listed] [No authors listed] Drugs R D. 2004;5(6):351-4. doi: 10.2165/00126839-200405060-00008. Drugs R D. 2004. PMID: 15563240 Review.
Palifermin is being developed for oral mucositis (stomatitis), for which it is undergoing review by the US FDA.At BioSquare-2004, Biovitrum stated that it has entered into an agreement with Amgen, under which Biovitrium has co-promotion rights to palifermin in Nordi …
Palifermin is being developed for oral mucositis (stomatitis), for which it is undergoing review by the US FDA.At BioSquare-2004, Bio …
Efficacy of palifermin in the hematopoietic stem cell transplant setting.
Panjwani M. Panjwani M. J Adv Pract Oncol. 2013 Mar;4(2):89-100. J Adv Pract Oncol. 2013. PMID: 25031987 Free PMC article. Review.
Palifermin is a recombinant human keratinocyte growth factor that stimulates proliferation and differentiation of epithelial cells. ...This article reviews the published literature on the efficacy of palifermin and makes evidence-based recommendations for the use of …
Palifermin is a recombinant human keratinocyte growth factor that stimulates proliferation and differentiation of epithelial cells. . …
Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models.
Finch PW, Mark Cross LJ, McAuley DF, Farrell CL. Finch PW, et al. J Cell Mol Med. 2013 Sep;17(9):1065-87. doi: 10.1111/jcmm.12091. J Cell Mol Med. 2013. PMID: 24151975 Free PMC article. Review.
Pre-clinical data initially demonstrated that a recombinant truncated KGF (palifermin) could reduce gastrointestinal injury and mortality resulting from a variety of toxic exposures. Furthermore, the use of palifermin in patients with hematological malignancies redu …
Pre-clinical data initially demonstrated that a recombinant truncated KGF (palifermin) could reduce gastrointestinal injury and morta …
Palifermin: in myelotoxic therapy-induced oral mucositis.
Siddiqui MA, Wellington K. Siddiqui MA, et al. Drugs. 2005;65(15):2139-46; discussion 2147-9. doi: 10.2165/00003495-200565150-00008. Drugs. 2005. PMID: 16225371 Review.
Palifermin, a recombinant human keratinocyte growth factor (KGF), mimics the actions of endogenous KGF and has shown efficacy in the management of myelotoxic therapy-induced oral mucositis in cancer patients. ...The drug was generally well tolerated, with skin/oral toxicit …
Palifermin, a recombinant human keratinocyte growth factor (KGF), mimics the actions of endogenous KGF and has shown efficacy in the …
Keratinocyte growth factor in focus: A comprehensive review from structural and functional aspects to therapeutic applications of palifermin.
Sadeghi S, Kalhor H, Panahi M, Abolhasani H, Rahimi B, Kalhor R, Mehrabi A, Vahdatinia M, Rahimi H. Sadeghi S, et al. Int J Biol Macromol. 2021 Nov 30;191:1175-1190. doi: 10.1016/j.ijbiomac.2021.09.151. Epub 2021 Oct 1. Int J Biol Macromol. 2021. PMID: 34606789 Review.
Palifermin is a recombinant protein generated from human keratinocyte growth factor (KGF) and imitates the function of endogenous KGF. ...Notwithstanding all merits, the clinical application of palifermin is limited owing to its instability and production challenges …
Palifermin is a recombinant protein generated from human keratinocyte growth factor (KGF) and imitates the function of endogenous KGF …
Palifermin for patients with haematological malignancies: shifting nursing practice from symptom relief to prevention of oral mucositis.
Fliedner M, Baguet B, Blankart J, Davies M, Henriques E, Leather A, Mazur E, Mihály K, Peeters L, Radványiné A, Sedlackova B. Fliedner M, et al. Eur J Oncol Nurs. 2007;11 Suppl 1:S19-26. doi: 10.1016/S1462-3889(07)70004-2. Eur J Oncol Nurs. 2007. PMID: 17540295 Review.
Palifermin was also well-tolerated; common adverse reactions reported included rash, pruritus, erythema, edema, pain, fever, arthralgia, mouth or tongue disorders, and taste alteration. In this article, nurses who are skilled in caring for patients undergoing HSCT review t …
Palifermin was also well-tolerated; common adverse reactions reported included rash, pruritus, erythema, edema, pain, fever, arthralg …
226 results