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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1986 1
1989 1
1991 1
1993 2
1998 1
1999 1
2000 1
2003 2
2005 1
2006 3
2008 4
2009 1
2010 3
2011 3
2014 1
2015 8
2016 3
2017 2
2018 5
2019 5
2020 13
2021 14
2022 9
2023 4
2024 7

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86 results

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Page 1
Tyrosine kinase inhibitors - a review on pharmacology, metabolism and side effects.
Hartmann JT, Haap M, Kopp HG, Lipp HP. Hartmann JT, et al. Curr Drug Metab. 2009 Jun;10(5):470-81. doi: 10.2174/138920009788897975. Curr Drug Metab. 2009. PMID: 19689244 Review.
In contrast, folliculitis is not common during administration of sorafenib and sunitinib, which target VEGFR, PDGFR, FLT3, and others, whereas both agents have been associated with subungual splinter hemorrhages. Periorbital edema is a common adverse effect of imati …
In contrast, folliculitis is not common during administration of sorafenib and sunitinib, which target VEGFR, PDGFR, FLT3, and others, where …
Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients.
Vañó-Galván S, Pirmez R, Hermosa-Gelbard A, Moreno-Arrones ÓM, Saceda-Corralo D, Rodrigues-Barata R, Jimenez-Cauhe J, Koh WL, Poa JE, Jerjen R, Trindade de Carvalho L, John JM, Salas-Callo CI, Vincenzi C, Yin L, Lo-Sicco K, Waskiel-Burnat A, Starace M, Zamorano JL, Jaén-Olasolo P, Piraccini BM, Rudnicka L, Shapiro J, Tosti A, Sinclair R, Bhoyrul B. Vañó-Galván S, et al. J Am Acad Dermatol. 2021 Jun;84(6):1644-1651. doi: 10.1016/j.jaad.2021.02.054. Epub 2021 Feb 24. J Am Acad Dermatol. 2021. PMID: 33639244
Systemic adverse effects included lightheadedness (1.7%), fluid retention (1.3%), tachycardia (0.9%), headache (0.4%), periorbital edema (0.3%), and insomnia (0.2%), leading to drug discontinuation in 29 patients (1.2%). No life-threatening adverse effects were o …
Systemic adverse effects included lightheadedness (1.7%), fluid retention (1.3%), tachycardia (0.9%), headache (0.4%), periorbital …
Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial.
DeAngelo DJ, Radia DH, George TI, Robinson WA, Quiery AT, Drummond MW, Bose P, Hexner EO, Winton EF, Horny HP, Tugnait M, Schmidt-Kittler O, Evans EK, Lin HM, Mar BG, Verstovsek S, Deininger MW, Gotlib J. DeAngelo DJ, et al. Nat Med. 2021 Dec;27(12):2183-2191. doi: 10.1038/s41591-021-01538-9. Epub 2021 Dec 6. Nat Med. 2021. PMID: 34873347 Free PMC article. Clinical Trial.
Maximum tolerated dose was not reached, and 200 mg and 300 mg daily were studied in dose-expansion cohorts. The most frequent adverse events observed were periorbital edema (69%), anemia (55%), diarrhea (45%), thrombocytopenia (44%) and nausea (44%). ...
Maximum tolerated dose was not reached, and 200 mg and 300 mg daily were studied in dose-expansion cohorts. The most frequent adverse events …
Biochemical Modulation and Pathophysiology of Migraine.
Chan C, Wei DY, Goadsby PJ. Chan C, et al. J Neuroophthalmol. 2019 Dec;39(4):470-479. doi: 10.1097/WNO.0000000000000875. J Neuroophthalmol. 2019. PMID: 31714319 Review.
Migraine is also associated with photosensitivity and cranial autonomic symptoms, which includes lacrimation, conjunctival injection, periorbital edema, ptosis, nasal congestion, and rhinorrhoea. This review will present the current understanding of migraine pathoph …
Migraine is also associated with photosensitivity and cranial autonomic symptoms, which includes lacrimation, conjunctival injection, per …
Surgical Burr-Assisted Lateral Osteotomy Technique in Septorhinoplasty.
Aysel A, Karatan B, Müderris T. Aysel A, et al. J Craniofac Surg. 2022 Mar-Apr 01;33(2):661-664. doi: 10.1097/SCS.0000000000007692. J Craniofac Surg. 2022. PMID: 33867512
The first group had lateral endonasal osteotomy with conventional guided osteotomes, and the second group had lateral osteotomy with surgical round burr. Edema and ecchymosis scoring systems were used on the postoperative first, third, and seventh day to evaluate po …
The first group had lateral endonasal osteotomy with conventional guided osteotomes, and the second group had lateral osteotomy with surgica …
Mechanisms in Graves Eye Disease: Apoptosis as the End Point of Insulin-Like Growth Factor 1 Receptor Inhibition.
Morshed SA, Ma R, Latif R, Davies TF. Morshed SA, et al. Thyroid. 2022 Apr;32(4):429-439. doi: 10.1089/thy.2021.0176. Thyroid. 2022. PMID: 34927457 Free PMC article.
Background: Graves' eye disease, also called Graves' orbitopathy (GO), is a potentially debilitating autoimmune disease associated with retro-orbital inflammation and tissue expansion, involving both fibroblasts and adipocytes, resulting in periorbital edema, worsen …
Background: Graves' eye disease, also called Graves' orbitopathy (GO), is a potentially debilitating autoimmune disease associated with retr …
Disease characteristics and clinical outcomes of adults and children with anti-MDA-5 antibody-associated myositis: a prospective observational bicentric study.
Dunga SK, Kavadichanda C, Gupta L, Naveen R, Agarwal V, Negi VS. Dunga SK, et al. Rheumatol Int. 2022 Jul;42(7):1155-1165. doi: 10.1007/s00296-021-04897-1. Epub 2021 May 29. Rheumatol Int. 2022. PMID: 34050793
Among cutaneous manifestations, majority (62%) had classic features (gottron's papules/sign, heliotrope rash) while 8 (38%) had cutaneous ulceration and 2 each had periorbital edema and tendon rupture. Eight (38%) were positive for anti-Ro-52 antibody. ...Indian adu …
Among cutaneous manifestations, majority (62%) had classic features (gottron's papules/sign, heliotrope rash) while 8 (38%) had cutaneous ul …
The Effects of Intraoperative Local Tranexamic Acid on Periorbital Edema and Ecchymosis in Septorhinoplasty.
İpek HD, Bezgin SÜ, Çakabay T, Çelebi Ş. İpek HD, et al. J Craniofac Surg. 2021 Sep 1;32(6):e526-e530. doi: 10.1097/SCS.0000000000007493. J Craniofac Surg. 2021. PMID: 33534311
The patient's photographs were taken on the first, third, and seventh postoperative days. Periorbital edema and ecchymoses were evaluated by the blinded author. ...There was no statistically significant between the sides in terms of upper eyelid edema (P = 0.315) on …
The patient's photographs were taken on the first, third, and seventh postoperative days. Periorbital edema and ecchymoses wer …
Pathophysiology of Graves' ophthalmopathy.
Stiebel-Kalish H, Robenshtok E, Gaton DD. Stiebel-Kalish H, et al. Pediatr Endocrinol Rev. 2010 Mar;7 Suppl 2:178-81. Pediatr Endocrinol Rev. 2010. PMID: 20467359 Review.
These processes lead to the clinical manifestations of proptosis, chemosis, periorbital edema, and altered ocular motility. Current evidence demonstrates that GO is not a result of hyperthyroidism but rather represents a second target of the underlying autoimmune pr …
These processes lead to the clinical manifestations of proptosis, chemosis, periorbital edema, and altered ocular motility. Cu …
External Splinting Is Not Mandatory After All Rhinoplasties: A Prospective Randomized Trial.
Cabbarzade C, Yücel ÖT, Sözen T, Ozgen B. Cabbarzade C, et al. Ann Plast Surg. 2021 Apr 1;86(4):376-380. doi: 10.1097/SAP.0000000000002710. Ann Plast Surg. 2021. PMID: 33720917 Clinical Trial.

RESULTS: On the second and seventh postoperative days, the levels of periorbital edema and ecchymosis were significantly lower in the patients with taping than in the patients with splints (P < 0.05 for each). ...Thus, the disadvantages of external splinting are

…
RESULTS: On the second and seventh postoperative days, the levels of periorbital edema and ecchymosis were significantly lower …
86 results