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1994 1
2000 1
2006 1
2007 1
2008 3
2010 2
2012 1
2013 6
2014 3
2015 2
2016 1
2017 2
2018 6
2019 5
2020 3
2021 4
2022 6
2023 3
2024 1

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45 results

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Page 1
Periventricular White Matter Hyperintensities and Functional Decline.
Dhamoon MS, Cheung YK, Bagci A, Alperin N, Sacco RL, Elkind MSV, Wright CB. Dhamoon MS, et al. J Am Geriatr Soc. 2018 Jan;66(1):113-119. doi: 10.1111/jgs.15149. Epub 2017 Nov 20. J Am Geriatr Soc. 2018. PMID: 29155435 Free PMC article.
The objective of the current study was to determine whether WMHV in particular brain regions is more predictive of functional decline. DESIGN: Prospective population-based study. ...
The objective of the current study was to determine whether WMHV in particular brain regions is more predictive of functional decline …
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.
Armstrong NJ, Mather KA, Sargurupremraj M, Knol MJ, Malik R, Satizabal CL, Yanek LR, Wen W, Gudnason VG, Dueker ND, Elliott LT, Hofer E, Bis J, Jahanshad N, Li S, Logue MA, Luciano M, Scholz M, Smith AV, Trompet S, Vojinovic D, Xia R, Alfaro-Almagro F, Ames D, Amin N, Amouyel P, Beiser AS, Brodaty H, Deary IJ, Fennema-Notestine C, Gampawar PG, Gottesman R, Griffanti L, Jack CR Jr, Jenkinson M, Jiang J, Kral BG, Kwok JB, Lampe L, C M Liewald D, Maillard P, Marchini J, Bastin ME, Mazoyer B, Pirpamer L, Rafael Romero J, Roshchupkin GV, Schofield PR, Schroeter ML, Stott DJ, Thalamuthu A, Trollor J, Tzourio C, van der Grond J, Vernooij MW, Witte VA, Wright MJ, Yang Q, Morris Z, Siggurdsson S, Psaty B, Villringer A, Schmidt H, Haberg AK, van Duijn CM, Jukema JW, Dichgans M, Sacco RL, Wright CB, Kremen WS, Becker LC, Thompson PM, Mosley TH, Wardlaw JM, Ikram MA, Adams HHH, Seshadri S, Sachdev PS, Smith SM, Launer L, Longstreth W, DeCarli C, Schmidt R, Fornage M, Debette S, Nyquist PA. Armstrong NJ, et al. Stroke. 2020 Jul;51(7):2111-2121. doi: 10.1161/STROKEAHA.119.027544. Epub 2020 Jun 10. Stroke. 2020. PMID: 32517579 Free PMC article.
BACKGROUND AND PURPOSE: Periventricular white matter hyperintensities (WMH; PVWMH) and deep WMH (DWMH) are regional classifications of WMH and reflect proposed differences in cause. ...Thirteen genes in the 17q25.1 locus were significant for both pheno …
BACKGROUND AND PURPOSE: Periventricular white matter hyperintensities (WMH; PVWMH) and deep WMH (DWMH) are regio …
White Matter Hyperintensities, Dopamine Loss, and Motor Deficits in De Novo Parkinson's Disease.
Jeong SH, Lee HS, Jung JH, Baik K, Lee YH, Yoo HS, Sohn YH, Chung SJ, Lee PH. Jeong SH, et al. Mov Disord. 2021 Jun;36(6):1411-1419. doi: 10.1002/mds.28510. Epub 2021 Jan 29. Mov Disord. 2021. PMID: 33513293
RESULTS: Periventricular and frontal white matter hyperintensities were generally associated with dopamine transporter availability in striatal subregions after adjusting for age at symptom onset, sex, disease duration, and vascular risk factors. There was an interaction effect b …
RESULTS: Periventricular and frontal white matter hyperintensities were generally associated with dopamine transporter availability in stria …
Periventricular white matter hyperintensity burden and cognitive impairment in early Parkinson's disease.
Huang X, Wen MC, Ng SY, Hartono S, Chia NS, Choi X, Tay KY, Au WL, Chan LL, Tan EK, Tan LC. Huang X, et al. Eur J Neurol. 2020 Jun;27(6):959-966. doi: 10.1111/ene.14192. Epub 2020 Mar 26. Eur J Neurol. 2020. PMID: 32124496
Cardiovascular risk was expressed as a modified Framingham 10-year cardiovascular risk score (mFRS). RESULTS: A total of 53.7% of this early PD cohort fulfilled the diagnostic criteria for PD-MCI. ...
Cardiovascular risk was expressed as a modified Framingham 10-year cardiovascular risk score (mFRS). RESULTS: A total of 53.7% of thi …
Venous Collagenosis as Pathogenesis of White Matter Hyperintensity.
Lahna D, Schwartz DL, Woltjer R, Black SE, Roese N, Dodge H, Boespflug EL, Keith J, Gao F, Ramirez J, Silbert LC. Lahna D, et al. Ann Neurol. 2022 Dec;92(6):992-1000. doi: 10.1002/ana.26487. Epub 2022 Sep 6. Ann Neurol. 2022. PMID: 36054513 Free PMC article.
OBJECTIVE: Periventricular white matter hyperintensities (pvWMHs) are commonly observed on MRI in older individuals and are associated with cognitive and motor decline. ...This study confirms the importance of changes to the venous system in con …
OBJECTIVE: Periventricular white matter hyperintensities (pvWMHs) are commonly observed on MRI in older i …
Periventricular white matter hyperintensities and the risk of dementia: a CREDOS study.
Kim S, Choi SH, Lee YM, Kim MJ, Kim YD, Kim JY, Park JH, Myung W, Na HR, Han HJ, Shim YS, Kim JH, Yoon SJ, Kim SY, Kim DK. Kim S, et al. Int Psychogeriatr. 2015 Dec;27(12):2069-77. doi: 10.1017/S1041610215001076. Epub 2015 Jul 27. Int Psychogeriatr. 2015. PMID: 26212042
The aim of this study was to ascertain the differential role of regional WMH in predicting progression from mild cognitive impairment (MCI) to different subtypes of dementia. ...Subcortical vascular dementia (SVD) was predicted by both PWMH (HR 16.14; 95% CI 1.97-13 …
The aim of this study was to ascertain the differential role of regional WMH in predicting progression from mild cognitive impairment …
Association between white matter lesions and Parkinson's disease: an impact on Postural/Gait difficulty phenotype and cognitive performance.
Sinani O, Dadouli K, Ntellas P, Kapsalaki EZ, Vlychou M, Raptis DG, Marogianni C, Markou K, Dardiotis E, Xiromerisiou G. Sinani O, et al. Neurol Res. 2022 Dec;44(12):1122-1131. doi: 10.1080/01616412.2022.2112378. Epub 2022 Aug 22. Neurol Res. 2022. PMID: 35994524
BACKGROUND: White matter hyperintensities (WMHs) may be observed on Magnetic Resonance Imaging (MRI) in patients with Parkinson disease with or without vascular risk factors. ...RESULTS: All vascular risk factors were associated with higher Fazekas score in both per …
BACKGROUND: White matter hyperintensities (WMHs) may be observed on Magnetic Resonance Imaging (MRI) in patients with Parkinson disea …
The Positional Relationship between Lacunae and White Matter Hyperintensity in Patients with Cerebral Small Vessel Disease.
An L, Yuan W, Wang Y, Li S, Zong C, Gao Y, Li Y, Wang L, Li YP, Ji Y, Xu Y. An L, et al. Curr Neurovasc Res. 2023;20(3):399-409. doi: 10.2174/1567202620666230721124707. Curr Neurovasc Res. 2023. PMID: 37488758
Univariate analysis indicated that age, fasting blood glucose, triglycerides, total cholesterol, highdensity lipoprotein, 24-hour and daytime and night systolic and diastolic blood pressure, nocturnal heart rate, heart rate variability, PI values of ipsilateral and contralateral …
Univariate analysis indicated that age, fasting blood glucose, triglycerides, total cholesterol, highdensity lipoprotein, 24-hour and daytim …
White matter hyperintensity burden predicts cognitive but not motor decline in Parkinson's disease: results from the Ontario Neurodegenerative Diseases Research Initiative.
Carvalho de Abreu DC, Pieruccini-Faria F, Sarquis-Adamson Y, Black A, Fraser J, Van Ooteghem K, Cornish B, Grimes D, Jog M, Masellis M, Steeves T, Nanayakkara N, Ramirez J, Scott C, Holmes M, Ozzoude M, Berezuk C, Symons S, Mohammad Hassan Haddad S, Arnott SR, Binns M, Strother S, Beaton D, Sunderland K, Theyers A, Tan B, Zamyadi M, Levine B, Orange JB, Roberts AC, Lou W, Sujanthan S, Breen DP, Marras C, Kwan D, Adamo S, Peltsch A, Troyer AK, Black SE, McLaughlin PM, Lang AE, McIlroy W, Bartha R; ONDRI Investigators; Montero-Odasso M. Carvalho de Abreu DC, et al. Eur J Neurol. 2023 Apr;30(4):920-933. doi: 10.1111/ene.15692. Epub 2023 Feb 14. Eur J Neurol. 2023. PMID: 36692250

RESULTS: Regression analysis adjusted for potential confounders showed that total and periventricular WMHs at baseline predicted decline in global cognition (p < 0.05). Also, total WMH burden predicted the decline of executive function (p < 0.05). ...WMH volum

RESULTS: Regression analysis adjusted for potential confounders showed that total and periventricular WMHs at baseline predicted decl …
The effects of white matter hyperintensities and amyloid deposition on Alzheimer dementia.
Gordon BA, Najmi S, Hsu P, Roe CM, Morris JC, Benzinger TL. Gordon BA, et al. Neuroimage Clin. 2015 Apr 30;8:246-52. doi: 10.1016/j.nicl.2015.04.017. eCollection 2015. Neuroimage Clin. 2015. PMID: 26106548 Free PMC article.
Participants obtained a T2-weighted scan as well as a positron emission tomography scan using (11)[C] Pittsburgh Compound B. Periventricular white matter hyperintensities (PVWMHs) and deep white matter hyperintensities (DWMHs) were measured on each T2 …
Participants obtained a T2-weighted scan as well as a positron emission tomography scan using (11)[C] Pittsburgh Compound B. Periventricu
45 results