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Page 1
Cetuximab Plus Concurrent Radiotherapy in Patients With Nasopharyngeal Carcinoma.
Yamauchi M, Sato Y, Ishida T, Minesaki A, Shimazaki E, Kuratomi Y. Yamauchi M, et al. In Vivo. 2023 Sep-Oct;37(5):2224-2228. doi: 10.21873/invivo.13323. In Vivo. 2023. PMID: 37652522 Free PMC article.
The 1- and 3-year overall survival rates were 85.7% and 47.6%, respectively. The most common adverse events (AEs) were pharyngeal mucositis (100%), radiation dermatitis (100%), anorexia (28.6%), weight loss (28.6%), acneiform rash (28.6%), and dry mouth (28.6%). Gra …
The 1- and 3-year overall survival rates were 85.7% and 47.6%, respectively. The most common adverse events (AEs) were pharyngeal …
Retrospective evaluation of the safety of low-level laser therapy/photobiomodulation in patients with head/neck cancer.
Genot-Klastersky MT, Paesmans M, Ameye L, Kayumba A, Beauvois S, Dragan T, Van Gestel D, Lalami Y, Klastersky JA. Genot-Klastersky MT, et al. Support Care Cancer. 2020 Jul;28(7):3015-3022. doi: 10.1007/s00520-019-05041-3. Epub 2019 Sep 9. Support Care Cancer. 2020. PMID: 31502227
The most common and distressing acute complication of such therapies is oral/pharyngeal mucositis that may be associated with severe morbidity and can interfere with the planned administration of therapy. ...
The most common and distressing acute complication of such therapies is oral/pharyngeal mucositis that may be associated with …
Objective evaluation of nutritional status using the prognostic nutritional index during and after chemoradiotherapy in Japanese patients with head and neck cancer: a retrospective study.
Fujiwara D, Tsubaki M, Takeda T, Miura M, Nishida S, Sakaguchi K. Fujiwara D, et al. Eur J Hosp Pharm. 2021 Sep;28(5):266-270. doi: 10.1136/ejhpharm-2019-001979. Epub 2019 Aug 17. Eur J Hosp Pharm. 2021. PMID: 34426479 Free PMC article.
The median length of hospitalisation after therapy was 5 days in patients with grades 1 and 2 and 10 days in patients with grade 3 oral and pharyngeal mucositis (p<0.05). The optimal cut-off PNI value as a criterion for hospital discharge was found to be 40.4 (gr …
The median length of hospitalisation after therapy was 5 days in patients with grades 1 and 2 and 10 days in patients with grade 3 oral and …
Enteral nutrition support and treatment toxicities in patients with head and neck cancer receiving definitive or adjuvant helical intensity-modulated radiotherapy with concurrent chemotherapy.
Blake CL, Brown TE, Pelecanos A, Moroney LB, Helios J, Hughes BGM, Chua B, Kenny LM. Blake CL, et al. Head Neck. 2023 Feb;45(2):417-430. doi: 10.1002/hed.27249. Epub 2022 Nov 25. Head Neck. 2023. PMID: 36433667
RESULTS: The threshold for patients needing 50% of estimated requirements via EN increased from week 3 to 4 for grade 2 oral/pharyngeal mucositis, dysgeusia, thick saliva and nausea, and for grade 3 dysphagia. ...
RESULTS: The threshold for patients needing 50% of estimated requirements via EN increased from week 3 to 4 for grade 2 oral/pharyngeal …
Clinical Outcomes of Intensity-modulated Carbon-ion Radiotherapy for Bone and Soft Tissue Tumors.
Takakusagi Y, Koge H, Kano K, Shima S, Tsuchida K, Mizoguchi N, Yoshida D, Kamada T, Katoh H. Takakusagi Y, et al. Anticancer Res. 2023 Jun;43(6):2777-2781. doi: 10.21873/anticanres.16446. Anticancer Res. 2023. PMID: 37247930
Acute toxicity of Grade 2 or higher was seen in 2 patients with Grade 2 pharyngeal mucositis. Late toxicities of Grade 2 or higher included 1 case each of Grade 2 neuralgia and peripheral neuropathy, as well as 1 case of Grade 3 fracture. ...
Acute toxicity of Grade 2 or higher was seen in 2 patients with Grade 2 pharyngeal mucositis. Late toxicities of Grade 2 or hi …
Real-world clinical outcomes in Japanese patients with locally advanced squamous cell carcinoma of the head and neck treated with radiotherapy plus cetuximab: a prospective observational study (JROSG12-2).
Ota Y, Kodaira T, Fujii H, Shimokawa M, Yokota T, Nakashima T, Monden N, Homma A, Ueda S, Akimoto T. Ota Y, et al. Int J Clin Oncol. 2022 Nov;27(11):1675-1683. doi: 10.1007/s10147-022-02228-3. Epub 2022 Aug 24. Int J Clin Oncol. 2022. PMID: 36001247
N stage, T stage, and comorbidity were significantly associated with TCR. Major AEs of grade 3 or higher were pharyngeal mucositis (48.5%), radiation dermatitis (45.6%), and oral mucositis (40.4%). ...
N stage, T stage, and comorbidity were significantly associated with TCR. Major AEs of grade 3 or higher were pharyngeal mucositis …
Patterns of dysphagia and acute toxicities in patients with head and neck cancer undergoing helical IMRT±concurrent chemotherapy.
Moroney LB, Helios J, Ward EC, Crombie J, Wockner LF, Burns CL, Spurgin AL, Blake C, Kenny L, Hughes BG. Moroney LB, et al. Oral Oncol. 2017 Jan;64:1-8. doi: 10.1016/j.oraloncology.2016.11.009. Epub 2016 Nov 25. Oral Oncol. 2017. PMID: 28024718
Over 70% had grade 2-3 dysguesia, xerostomia, and thick saliva, and >50% experienced grade 2-3 pharyngeal mucositis, oral mucositis, and nausea. 13% patients declined to NBM requiring complete enteral nutrition, 25% required enteral nutrition but maintained some …
Over 70% had grade 2-3 dysguesia, xerostomia, and thick saliva, and >50% experienced grade 2-3 pharyngeal mucositis, oral m …
A randomised controlled trial of Caphosol mouthwash in management of radiation-induced mucositis in head and neck cancer.
Wong KH, Kuciejewska A, Sharabiani MTA, Ng-Cheng-Hin B, Hoy S, Hurley T, Rydon J, Grove L, Santos A, Ryugenji M, Bhide SA, Nutting CM, Harrington KJ, Newbold KL. Wong KH, et al. Radiother Oncol. 2017 Feb;122(2):207-211. doi: 10.1016/j.radonc.2016.06.015. Epub 2016 Jul 5. Radiother Oncol. 2017. PMID: 27393218 Free PMC article. Clinical Trial.
The primary endpoint was the incidence of severe OM (CTCAE grade 3) during and up to week 8 post-radiotherapy. Secondary endpoints include pharyngeal mucositis, dysphagia, pain and quality of life. RESULTS: The intervention (n=108) and control (n=107) arms were well …
The primary endpoint was the incidence of severe OM (CTCAE grade 3) during and up to week 8 post-radiotherapy. Secondary endpoints include …
Nutrition outcomes and treatment toxicities in patients with head and neck cancer receiving helical intensity-modulated radiotherapy.
Blake C, Lai R, Brown T, Pelecanos A, Moroney L, Helios J, Smith D, Hughes BGM, Kenny L, Chua B, Bauer J. Blake C, et al. J Hum Nutr Diet. 2024 Feb;37(1):182-192. doi: 10.1111/jhn.13243. Epub 2023 Sep 22. J Hum Nutr Diet. 2024. PMID: 37737485
Nausea, adjusted for baseline dysphagia, in high nutritional risk patients and nausea, dysphagia and pharyngeal mucositis in low nutritional risk patients were significant factors in explaining the percentage loss in baseline weight to treatment completion. ...
Nausea, adjusted for baseline dysphagia, in high nutritional risk patients and nausea, dysphagia and pharyngeal mucositis in l …
A Meta-Analysis on the Efficacy of Zinc in Oral Mucositis during Cancer Chemo and/or Radiotherapy-An Evidence-Based Approach.
Chaitanya NC, Shugufta K, Suvarna C, Bhopal T, Mekala S, Ponnuru H, Madathanapalle R, Patel M, Abhyankar S, Reddy C, Deveneni P. Chaitanya NC, et al. J Nutr Sci Vitaminol (Tokyo). 2019;65(2):184-191. doi: 10.3177/jnsv.65.184. J Nutr Sci Vitaminol (Tokyo). 2019. PMID: 31061288 Free article.
The onset of the reaction was delayed and hastened healing. Pharyngeal mucositis, pain and quality of life of the individuals received no effect from zinc therapy....
The onset of the reaction was delayed and hastened healing. Pharyngeal mucositis, pain and quality of life of the individuals …
19 results