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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 1
2000 3
2003 1
2004 1
2005 1
2006 1
2007 1
2008 1
2009 1
2010 4
2012 1
2013 2
2014 2
2015 4
2016 2
2017 2
2018 6
2019 6
2020 4
2021 7
2022 4
2023 9
2024 2

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65 results

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Page 1
Systematic Review and Meta-Analysis of Dietary Interventions and Microbiome in Phenylketonuria.
Ubaldi F, Frangella C, Volpini V, Fortugno P, Valeriani F, Romano Spica V. Ubaldi F, et al. Int J Mol Sci. 2023 Dec 13;24(24):17428. doi: 10.3390/ijms242417428. Int J Mol Sci. 2023. PMID: 38139256 Free PMC article. Review.
Inborn errors of metabolism (IEMs) comprise a diverse group of monogenic disorders caused by enzyme deficiencies that result either in a toxic accumulation of metabolic intermediates or a shortage of essential end-products. Certain IEMs, like phenylketonuria (PKU), necessi …
Inborn errors of metabolism (IEMs) comprise a diverse group of monogenic disorders caused by enzyme deficiencies that result either in a tox …
A systematic review of bone mineral density and fractures in phenylketonuria.
Hansen KE, Ney D. Hansen KE, et al. J Inherit Metab Dis. 2014 Nov;37(6):875-80. doi: 10.1007/s10545-014-9735-2. Epub 2014 Jul 9. J Inherit Metab Dis. 2014. PMID: 25005329 Free PMC article. Review.
INTRODUCTION: Our objective was to systematically review and analyze published data on bone mineral density (BMD) and fracture rates in patients with phenylketonuria (PKU), and relationships between BMD and phenylalanine levels. ...
INTRODUCTION: Our objective was to systematically review and analyze published data on bone mineral density (BMD) and fracture rates in pati …
Bone health in phenylketonuria: a systematic review and meta-analysis.
Demirdas S, Coakley KE, Bisschop PH, Hollak CE, Bosch AM, Singh RH. Demirdas S, et al. Orphanet J Rare Dis. 2015 Feb 15;10:17. doi: 10.1186/s13023-015-0232-y. Orphanet J Rare Dis. 2015. PMID: 25758373 Free PMC article. Review.
Patients with Phenylketonuria (PKU) reportedly have decreased bone mineral density (BMD). ...
Patients with Phenylketonuria (PKU) reportedly have decreased bone mineral density (BMD). ...
Systematic Review and Meta-Analysis of Neuropsychiatric Symptoms and Executive Functioning in Adults With Phenylketonuria.
Bilder DA, Noel JK, Baker ER, Irish W, Chen Y, Merilainen MJ, Prasad S, Winslow BJ. Bilder DA, et al. Dev Neuropsychol. 2016 May-Jun;41(4):245-260. doi: 10.1080/87565641.2016.1243109. Epub 2016 Nov 2. Dev Neuropsychol. 2016. PMID: 27805419 Free PMC article. Review.
This systematic review and meta-analysis (MA) investigates the impact of elevated blood phenylalanine (Phe) on neuropsychiatric symptoms in adults with phenylketonuria (PKU). The meta-analysis of PKU is challenging because high-quality evidence is lacking due to the limite …
This systematic review and meta-analysis (MA) investigates the impact of elevated blood phenylalanine (Phe) on neuropsychiatric symptoms in …
Sapropterin dihydrochloride for phenylketonuria.
Somaraju UR, Merrin M. Somaraju UR, et al. Cochrane Database Syst Rev. 2015 Mar 27;2015(3):CD008005. doi: 10.1002/14651858.CD008005.pub4. Cochrane Database Syst Rev. 2015. PMID: 25812600 Free PMC article. Review.
BACKGROUND: Phenylketonuria results from a deficiency of the enzyme phenylalanine hydroxylase. ...The second trial screened 90 children (4 to 12 years) with phenylketonuria whose diet was restricted, for responsiveness to sapropterin. ...
BACKGROUND: Phenylketonuria results from a deficiency of the enzyme phenylalanine hydroxylase. ...The second trial screened 90 childr …
Dietary interventions for phenylketonuria.
Jameson E, Remmington T. Jameson E, et al. Cochrane Database Syst Rev. 2020 Jul 16;7(7):CD001304. doi: 10.1002/14651858.CD001304.pub3. Cochrane Database Syst Rev. 2020. PMID: 32672365 Free PMC article.
BACKGROUND: Phenylketonuria is an inherited disease treated with dietary restriction of the amino acid phenylalanine. ...Blood phenylalanine levels were significantly lower in participants with phenylketonuria following a low-phenylalanine diet compared to those on …
BACKGROUND: Phenylketonuria is an inherited disease treated with dietary restriction of the amino acid phenylalanine. ...Blood phenyl …
OVERWEIGHT AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH PHENYLKETONURIA: A SYSTEMATIC REVIEW.
Sena BDS, Andrade MIS, Silva APFD, Dourado KF, Silva ALF. Sena BDS, et al. Rev Paul Pediatr. 2020 Mar 9;38:e2018201. doi: 10.1590/1984-0462/2020/38/2018201. eCollection 2020. Rev Paul Pediatr. 2020. PMID: 32159642 Free PMC article.
DATA SYNTHESIS: A total of 16 articles were identified and, after screening procedures, 6 studies were selected for the review. Overweight in children and adolescents with phenylketonuria was a frequent occurence in the studies included in this review, ranging from 7.8 to …
DATA SYNTHESIS: A total of 16 articles were identified and, after screening procedures, 6 studies were selected for the review. Overweight i …
Tyrosine supplementation for phenylketonuria.
Remmington T, Smith S. Remmington T, et al. Cochrane Database Syst Rev. 2021 Jan 4;1(1):CD001507. doi: 10.1002/14651858.CD001507.pub4. Cochrane Database Syst Rev. 2021. PMID: 33427303 Free PMC article.
BACKGROUND: Phenylketonuria is an inherited disease for which the main treatment is the dietary restriction of the amino acid phenylalanine. ...A deficiency of the amino acid tyrosine has been suggested as a cause of some of the neuropsychological problems exhibited in …
BACKGROUND: Phenylketonuria is an inherited disease for which the main treatment is the dietary restriction of the amino acid phenyla …
Phenylalanine Tolerance over Time in Phenylketonuria: A Systematic Review and Meta-Analysis.
Pinto A, Ilgaz F, Evans S, van Dam E, Rocha JC, Karabulut E, Hickson M, Daly A, MacDonald A. Pinto A, et al. Nutrients. 2023 Aug 8;15(16):3506. doi: 10.3390/nu15163506. Nutrients. 2023. PMID: 37630696 Free PMC article. Review.
In phenylketonuria (PKU), natural protein tolerance is defined as the maximum natural protein intake maintaining a blood phenylalanine (Phe) concentration within a target therapeutic range. ...
In phenylketonuria (PKU), natural protein tolerance is defined as the maximum natural protein intake maintaining a blood phenylalanin …
Tyrosine supplementation for phenylketonuria.
Webster D, Wildgoose J. Webster D, et al. Cochrane Database Syst Rev. 2013 Jun 5;2013(6):CD001507. doi: 10.1002/14651858.CD001507.pub3. Cochrane Database Syst Rev. 2013. PMID: 23737086 Free PMC article. Updated. Review.
BACKGROUND: Phenylketonuria is an inherited disease for which the main treatment is the dietary restriction of the amino acid phenylalanine. ...A deficiency of the amino acid tyrosine has been suggested as a cause of some of the neuropsychological problems exhibited in …
BACKGROUND: Phenylketonuria is an inherited disease for which the main treatment is the dietary restriction of the amino acid phenyla …
65 results