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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1960 1
1964 2
1965 2
1966 5
1967 2
1968 1
1970 2
1971 4
1972 4
1973 7
1974 5
1975 44
1976 40
1977 36
1978 31
1979 38
1980 43
1981 52
1982 52
1983 86
1984 85
1985 101
1986 97
1987 123
1988 124
1989 155
1990 170
1991 184
1992 191
1993 247
1994 235
1995 244
1996 284
1997 275
1998 281
1999 281
2000 295
2001 314
2002 344
2003 335
2004 324
2005 365
2006 382
2007 414
2008 417
2009 391
2010 468
2011 548
2012 590
2013 602
2014 633
2015 655
2016 570
2017 639
2018 631
2019 657
2020 762
2021 823
2022 862
2023 873
2024 380

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15,095 results

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Quoted phrase not found in phrase index: "Pheochromocytoma-islet cell tumor syndrome"
Page 1
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Kumariya S, Ubba V, Jha RK, Gayen JR. Kumariya S, et al. Autophagy. 2021 Oct;17(10):2706-2733. doi: 10.1080/15548627.2021.1938914. Epub 2021 Jun 23. Autophagy. 2021. PMID: 34161185 Free PMC article. Review.
Recent discoveries demonstrate a significant role of autophagy in the pathogenesis of PCOS. Defective autophagy in the follicular cells during different stages of follicles is observed in the PCOS ovary. Exploring different autophagy pathways provides a platform for …
Recent discoveries demonstrate a significant role of autophagy in the pathogenesis of PCOS. Defective autophagy in the follicular cells …
Immuno-oncology.
Gallimore A, Tournier C. Gallimore A, et al. Essays Biochem. 2023 Sep 28;67(6):903. doi: 10.1042/EBC20230071. Essays Biochem. 2023. PMID: 37767785
Today, it is accepted that the ability to evade the attention of the immune system is an essential hallmark of cancer. Critically, as tumours progress, cancer cells can protect themselves from the immune system's natural ability to fight the disease. This observa …
Today, it is accepted that the ability to evade the attention of the immune system is an essential hallmark of cancer. Critically, as tum …
Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment.
Kershner LJ, Choi K, Wu J, Zhang X, Perrino M, Salomonis N, Shern JF, Ratner N. Kershner LJ, et al. JCI Insight. 2022 Sep 22;7(18):e154513. doi: 10.1172/jci.insight.154513. JCI Insight. 2022. PMID: 36134665 Free PMC article.
To define alterations early in tumor formation, we studied nerve tumors in neurofibromatosis 1 (NF1), a tumor predisposition syndrome. Affected individuals develop neurofibromas, benign tumors driven by NF1 loss in Schwann cells (S …
To define alterations early in tumor formation, we studied nerve tumors in neurofibromatosis 1 (NF1), a tumor predispos …
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication.
Chen M, He C, Zhu K, Chen Z, Meng Z, Jiang X, Cai J, Yang C, Zuo Z. Chen M, et al. Theranostics. 2022 Jan 1;12(2):782-795. doi: 10.7150/thno.67167. eCollection 2022. Theranostics. 2022. PMID: 34976213 Free PMC article.
Rationale: Polycystic ovary syndrome (PCOS) is closely linked to follicular dysplasia and impaired bidirectional oocyte-granulosa cell (GC) communication. ...In addition, TZP disruption and CAMK2B upregulation were also observed in samples from PCOS patients. …
Rationale: Polycystic ovary syndrome (PCOS) is closely linked to follicular dysplasia and impaired bidirectional oocyte-granulosa …
Alternative RNA splicing defects in pediatric cancers: new insights in tumorigenesis and potential therapeutic vulnerabilities.
Venkataramany AS, Schieffer KM, Lee K, Cottrell CE, Wang PY, Mardis ER, Cripe TP, Chandler DS. Venkataramany AS, et al. Ann Oncol. 2022 Jun;33(6):578-592. doi: 10.1016/j.annonc.2022.03.011. Epub 2022 Mar 23. Ann Oncol. 2022. PMID: 35339647 Free article. Review.
RESULTS: Published dysregulated splicing events can be categorized as exon inclusion, exon exclusion, splicing factor up-regulation, or splice site alterations. We observe these phenomena in cancer predisposition syndromes (Lynch syndrome, Li-Fraumeni synd …
RESULTS: Published dysregulated splicing events can be categorized as exon inclusion, exon exclusion, splicing factor up-regulation, or spli …
Neurological adverse events related to immune-checkpoint inhibitors in Spain: a retrospective cohort study.
Fonseca E, Cabrera-Maqueda JM, Ruiz-García R, Naranjo L, Diaz-Pedroche C, Velasco R, Macias-Gómez A, Milisenda JC, Muñoz-Farjas E, Pascual-Goñi E, Gállego Perez-Larraya J, Saiz A, Dalmau J, Blanco Y, Graus F, Martinez-Hernandez E; Neuro-ICI-Spain study group. Fonseca E, et al. Lancet Neurol. 2023 Dec;22(12):1150-1159. doi: 10.1016/S1474-4422(23)00335-6. Lancet Neurol. 2023. PMID: 37977714 Review.
BACKGROUND: Neurological immune-related adverse events associated with immune checkpoint inhibitors can have several clinical manifestations, but the syndromes and prognostic factors are still not well known. We aimed to characterise and group the clinical features, with a …
BACKGROUND: Neurological immune-related adverse events associated with immune checkpoint inhibitors can have several clinical manifestations …
Genomic Patterns of Malignant Peripheral Nerve Sheath Tumor (MPNST) Evolution Correlate with Clinical Outcome and Are Detectable in Cell-Free DNA.
Cortes-Ciriano I, Steele CD, Piculell K, Al-Ibraheemi A, Eulo V, Bui MM, Chatzipli A, Dickson BC, Borcherding DC, Feber A, Galor A, Hart J, Jones KB, Jordan JT, Kim RH, Lindsay D, Miller C, Nishida Y, Proszek PZ, Serrano J, Sundby RT, Szymanski JJ, Ullrich NJ, Viskochil D, Wang X, Snuderl M, Park PJ, Flanagan AM, Hirbe AC, Pillay N, Miller DT; Genomics of MPNST (GeM) Consortium. Cortes-Ciriano I, et al. Cancer Discov. 2023 Mar 1;13(3):654-671. doi: 10.1158/2159-8290.CD-22-0786. Cancer Discov. 2023. PMID: 36598417 Free PMC article.
Tumors with H3K27me3 loss evolve through extensive chromosomal losses followed by whole-genome doubling and chromosome 8 amplification, and show lower levels of immune cell infiltration. Retention of H3K27me3 leads to extensive genomic instability, but an immune …
Tumors with H3K27me3 loss evolve through extensive chromosomal losses followed by whole-genome doubling and chromosome 8 amplificatio …
Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers.
Jahn A, Rump A, Widmann TJ, Heining C, Horak P, Hutter B, Paramasivam N, Uhrig S, Gieldon L, Drukewitz S, Kübler A, Bermudez M, Hackmann K, Porrmann J, Wagner J, Arlt M, Franke M, Fischer J, Kowalzyk Z, William D, Weth V, Oster S, Fröhlich M, Hüllein J, Valle González C, Kreutzfeldt S, Mock A, Heilig CE, Lipka DB, Möhrmann L, Hanf D, Oleś M, Teleanu V, Allgäuer M, Ruhnke L, Kutz O, Knurr A, Laßmann A, Endris V, Neumann O, Penzel R, Beck K, Richter D, Winter U, Wolf S, Pfütze K, Geörg C, Meißburger B, Buchhalter I, Augustin M, Aulitzky WE, Hohenberger P, Kroiss M, Schirmacher P, Schlenk RF, Keilholz U, Klauschen F, Folprecht G, Bauer S, Siveke JT, Brandts CH, Kindler T, Boerries M, Illert AL, von Bubnoff N, Jost PJ, Metzeler KH, Bitzer M, Schulze-Osthoff K, von Kalle C, Brors B, Stenzinger A, Weichert W, Hübschmann D, Fröhling S, Glimm H, Schröck E, Klink B. Jahn A, et al. Ann Oncol. 2022 Nov;33(11):1186-1199. doi: 10.1016/j.annonc.2022.07.008. Epub 2022 Aug 18. Ann Oncol. 2022. PMID: 35988656 Free article.
BACKGROUND: Germline variant evaluation in precision oncology opens new paths toward the identification of patients with genetic tumor risk syndromes and the exploration of therapeutic relevance. ...Another 5% of patients (n = 75) were heterozygous carriers for rece …
BACKGROUND: Germline variant evaluation in precision oncology opens new paths toward the identification of patients with genetic tumor …
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM. Jiang XL, et al. Front Endocrinol (Lausanne). 2022 Nov 9;13:962154. doi: 10.3389/fendo.2022.962154. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36465612 Free PMC article. Clinical Trial.
Then, we detected apoptotic and mitochondrial function, and observed mitochondria in ovarian granular cells by transmission electron microscopy. ...In addition, CFDT improved ovarian function, reduced inflammatory response, inhibited apoptosis of granular cells …
Then, we detected apoptotic and mitochondrial function, and observed mitochondria in ovarian granular cells by transmission el …
Hereditary SWI/SNF complex deficiency syndromes.
Agaimy A, Foulkes WD. Agaimy A, et al. Semin Diagn Pathol. 2018 May;35(3):193-198. doi: 10.1053/j.semdp.2018.01.002. Epub 2018 Feb 1. Semin Diagn Pathol. 2018. PMID: 29397238 Review.
Atypical teratoid/rhabdoid tumors (AT/RT) and renal/extrarenal malignant rhabdoid tumors of childhood, epithelioid sarcoma and small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) represent the most commonly recognized SWI/SNF-driven neoplasms …
Atypical teratoid/rhabdoid tumors (AT/RT) and renal/extrarenal malignant rhabdoid tumors of childhood, epithelioid sarcoma and …
15,095 results
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