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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1954 1
1957 2
1958 1
1964 2
1965 2
1966 1
1967 4
1968 15
1969 7
1970 17
1971 28
1972 25
1973 40
1974 44
1975 61
1976 47
1977 42
1978 42
1979 51
1980 47
1981 45
1982 41
1983 77
1984 89
1985 113
1986 115
1987 116
1988 114
1989 161
1990 172
1991 186
1992 180
1993 190
1994 224
1995 258
1996 276
1997 244
1998 250
1999 281
2000 286
2001 354
2002 366
2003 416
2004 393
2005 406
2006 461
2007 493
2008 480
2009 492
2010 549
2011 617
2012 691
2013 706
2014 740
2015 737
2016 725
2017 878
2018 876
2019 889
2020 1002
2021 1023
2022 937
2023 882
2024 361

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17,314 results

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Quoted phrase not found in phrase index: "Pheochromocytoma-islet cell tumor syndrome"
Page 1
CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy.
Pan K, Farrukh H, Chittepu VCSR, Xu H, Pan CX, Zhu Z. Pan K, et al. J Exp Clin Cancer Res. 2022 Mar 31;41(1):119. doi: 10.1186/s13046-022-02327-z. J Exp Clin Cancer Res. 2022. PMID: 35361234 Free PMC article. Review.
However, CAR immunotherapy in solid tumors lags significantly behind. Some of the major hurdles for CAR immunotherapy in solid tumors include CAR T cell manufacturing, lack of tumor-specific antigens, inefficient CAR T cell trafficking and infil …
However, CAR immunotherapy in solid tumors lags significantly behind. Some of the major hurdles for CAR immunotherapy in solid tum …
T-cell-engaging bispecific antibodies in cancer.
van de Donk NWCJ, Zweegman S. van de Donk NWCJ, et al. Lancet. 2023 Jul 8;402(10396):142-158. doi: 10.1016/S0140-6736(23)00521-4. Epub 2023 Jun 1. Lancet. 2023. PMID: 37271153 Review.
T-cell-engaging bispecific antibodies (BsAbs) simultaneously bind to antigens on tumour cells and CD3 subunits on T cells. This simultaneous binding results in the recruitment of T cells to the tumour, followed by T-cell activation …
T-cell-engaging bispecific antibodies (BsAbs) simultaneously bind to antigens on tumour cells and CD3 subunits on T …
CAR-NK cells: A promising cellular immunotherapy for cancer.
Xie G, Dong H, Liang Y, Ham JD, Rizwan R, Chen J. Xie G, et al. EBioMedicine. 2020 Sep;59:102975. doi: 10.1016/j.ebiom.2020.102975. Epub 2020 Aug 24. EBioMedicine. 2020. PMID: 32853984 Free PMC article. Review.
Natural Killer (NK) cells and CD8(+) cytotoxic T cells are two types of immune cells that can kill target cells through similar cytotoxic mechanisms. ...CAR-NK cells could be engineered to target diverse antigens, enhance proliferation and persi …
Natural Killer (NK) cells and CD8(+) cytotoxic T cells are two types of immune cells that can kill target cells …
Insulin and the polycystic ovary syndrome.
Macut D, Bjekić-Macut J, Rahelić D, Doknić M. Macut D, et al. Diabetes Res Clin Pract. 2017 Aug;130:163-170. doi: 10.1016/j.diabres.2017.06.011. Epub 2017 Jun 12. Diabetes Res Clin Pract. 2017. PMID: 28646699 Review.
Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy among women during reproductive age. ...Thiazolidinediones should be reserved for women intolerant of or refractory to metformin, while glucagon-like peptide 1 analogues has a potential therapeutic use i …
Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy among women during reproductive age. ...Thiazolidinediones shou …
Reactions Related to CAR-T Cell Therapy.
Miao L, Zhang Z, Ren Z, Li Y. Miao L, et al. Front Immunol. 2021 Apr 28;12:663201. doi: 10.3389/fimmu.2021.663201. eCollection 2021. Front Immunol. 2021. PMID: 33995389 Free PMC article. Review.
This therapeutic approach has been used to treat hematological malignancies solid tumors. However, it is associated with adverse reactions such as, cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), off-tar …
This therapeutic approach has been used to treat hematological malignancies solid tumors. However, it is associated with adverse reac …
Engineered T cells: the promise and challenges of cancer immunotherapy.
Fesnak AD, June CH, Levine BL. Fesnak AD, et al. Nat Rev Cancer. 2016 Aug 23;16(9):566-81. doi: 10.1038/nrc.2016.97. Nat Rev Cancer. 2016. PMID: 27550819 Free PMC article. Review.
The immune system evolved to distinguish non-self from self to protect the organism. As cancer is derived from our own cells, immune responses to dysregulated cell growth present a unique challenge. ...Recent clinical trials using T cells engineered to …
The immune system evolved to distinguish non-self from self to protect the organism. As cancer is derived from our own cells, immune …
Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome.
Gong Y, Luo S, Fan P, Zhu H, Li Y, Huang W. Gong Y, et al. Reprod Biol Endocrinol. 2020 Dec 7;18(1):121. doi: 10.1186/s12958-020-00677-x. Reprod Biol Endocrinol. 2020. PMID: 33287836 Free PMC article. Clinical Trial.
BACKGROUND: It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlying mechanism of GH in OS and apoptosis in granulosa …
BACKGROUND: It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by a …
Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis.
Kite C, Lahart IM, Afzal I, Broom DR, Randeva H, Kyrou I, Brown JE. Kite C, et al. Syst Rev. 2019 Feb 12;8(1):51. doi: 10.1186/s13643-019-0962-3. Syst Rev. 2019. PMID: 30755271 Free PMC article.
METHODS: Relevant databases were searched (June 2017) with no time limit for trial inclusion. Eligible trials employed a randomised or quasi-randomised design to measure the chronic effects of exercise, or exercise and diet in women with PCOS. ...
METHODS: Relevant databases were searched (June 2017) with no time limit for trial inclusion. Eligible trials employed a randomise …
MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors.
Borcherding DC, Amin NV, He K, Zhang X, Lyu Y, Dehner C, Bhatia H, Gothra A, Daud L, Ruminski P, Pratilas CA, Pollard K, Sundby T, Widemann BC, Hirbe AC. Borcherding DC, et al. Clin Cancer Res. 2023 Apr 14;29(8):1592-1604. doi: 10.1158/1078-0432.CCR-22-3722. Clin Cancer Res. 2023. PMID: 36799629 Free PMC article.
PURPOSE: Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas with limited treatment options and poor survival rates. ...CONCLUSIONS: These data provide the preclinical rationale for the development of a phase I clinical trial of deucravac …
PURPOSE: Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas with limited treatment options and poor survival ra …
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication.
Chen M, He C, Zhu K, Chen Z, Meng Z, Jiang X, Cai J, Yang C, Zuo Z. Chen M, et al. Theranostics. 2022 Jan 1;12(2):782-795. doi: 10.7150/thno.67167. eCollection 2022. Theranostics. 2022. PMID: 34976213 Free PMC article.
Rationale: Polycystic ovary syndrome (PCOS) is closely linked to follicular dysplasia and impaired bidirectional oocyte-granulosa cell (GC) communication. ...
Rationale: Polycystic ovary syndrome (PCOS) is closely linked to follicular dysplasia and impaired bidirectional oocyte-granulosa …
17,314 results
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