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Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY. Asa SL, et al. Endocr Pathol. 2022 Mar;33(1):6-26. doi: 10.1007/s12022-022-09703-7. Epub 2022 Mar 15. Endocr Pathol. 2022. PMID: 35291028 Review.
Anterior lobe tumors include (i) well-differentiated adenohypophyseal tumors that are now classified as pituitary neuroendocrine tumors (PitNETs; formerly known as pituitary adenomas), (ii) pituitary blastoma, and (iii) the two types of craniopharyngioma. The new WH …
Anterior lobe tumors include (i) well-differentiated adenohypophyseal tumors that are now classified as pituitary neuroendocrine tumors (Pit …
DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.
Schultz KAP, Williams GM, Kamihara J, Stewart DR, Harris AK, Bauer AJ, Turner J, Shah R, Schneider K, Schneider KW, Carr AG, Harney LA, Baldinger S, Frazier AL, Orbach D, Schneider DT, Malkin D, Dehner LP, Messinger YH, Hill DA. Schultz KAP, et al. Clin Cancer Res. 2018 May 15;24(10):2251-2261. doi: 10.1158/1078-0432.CCR-17-3089. Epub 2018 Jan 17. Clin Cancer Res. 2018. PMID: 29343557 Free PMC article. Review.
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, particularly Sertoli-Leydig cell tumor, individuals with pathogenic germline DICER1 variants may also develop lung cysts, cystic nephroma, renal sarcoma and Wi …
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, particularly Sertol …
Imaging of DICER1 syndrome.
Guillerman RP, Foulkes WD, Priest JR. Guillerman RP, et al. Pediatr Radiol. 2019 Oct;49(11):1488-1505. doi: 10.1007/s00247-019-04429-x. Epub 2019 Oct 16. Pediatr Radiol. 2019. PMID: 31620849 Review.
The hallmarks of DICER1 syndrome are certain rare tumors including pleuropulmonary blastoma; cystic nephroma; ovarian Sertoli-Leydig cell tumor; sarcomas of the cervix, kidneys and cerebrum; pituitary blastoma; ciliary body medulloepithelioma; and nasal chondromesen …
The hallmarks of DICER1 syndrome are certain rare tumors including pleuropulmonary blastoma; cystic nephroma; ovarian Sertoli-Leydig cell tu …
Clinical Outcomes and Complications of Pituitary Blastoma.
Liu APY, Kelsey MM, Sabbaghian N, Park SH, Deal CL, Esbenshade AJ, Ploner O, Peet A, Traunecker H, Ahmed YHE, Zacharin M, Tiulpakov A, Lapshina AM, Walter AW, Dutta P, Rai A, Korbonits M, de Kock L, Nichols KE, Foulkes WD, Priest JR. Liu APY, et al. J Clin Endocrinol Metab. 2021 Jan 23;106(2):351-363. doi: 10.1210/clinem/dgaa857. J Clin Endocrinol Metab. 2021. PMID: 33236116 Free PMC article.
CONTEXT: Pituitary blastoma is a rare, dysontogenetic hypophyseal tumor of infancy first described in 2008, strongly suggestive of DICER1 syndrome. ...PATIENTS: Patients included children with pituitary blastoma. INTERVENTIONS: Genetic testing, surgery …
CONTEXT: Pituitary blastoma is a rare, dysontogenetic hypophyseal tumor of infancy first described in 2008, strongly suggestiv …
Pituitary blastoma.
Scheithauer BW, Kovacs K, Horvath E, Kim DS, Osamura RY, Ketterling RP, Lloyd RV, Kim OL. Scheithauer BW, et al. Acta Neuropathol. 2008 Dec;116(6):657-66. doi: 10.1007/s00401-008-0388-9. Epub 2008 Jun 13. Acta Neuropathol. 2008. PMID: 18551299
Ultrastructurally, the tissue resembled fetal pituitary of 10-12 weeks gestation and contained fully differentiated corticotrophs and somatotrophs, scant cells of glycoprotein-hormone producing type with small secretory granules, and glandular epithelial cells consistent with com …
Ultrastructurally, the tissue resembled fetal pituitary of 10-12 weeks gestation and contained fully differentiated corticotrophs and somato …
Paediatric Pituitary Adenomas: Clinical Presentation, Biochemical Profile and Long-Term Prognosis.
Jayant SS, Pal R, Rai A, Gupta K, Radotra BD, Walia R, Dhandapani S, Tripathi M, Ahuja CK, Gupta P, Bhansali A, Das L, Dutta P. Jayant SS, et al. Neurol India. 2022 Jan-Feb;70(1):304-311. doi: 10.4103/0028-3886.338667. Neurol India. 2022. PMID: 35263901 Free article.
Corticotropinomas (32.4%) and somatotropinomas (25.7%) were common, with 1 case of TSHoma and pituitary blastoma. The most common presentation was headache (57%) overall and menstrual irregularities (64.2%) in girls. ...
Corticotropinomas (32.4%) and somatotropinomas (25.7%) were common, with 1 case of TSHoma and pituitary blastoma. The most com …
Benign and Malignant Tumors of the Pituitary Gland.
Albano L, Losa M, Barzaghi LR, Mortini P. Albano L, et al. Adv Exp Med Biol. 2023;1405:281-297. doi: 10.1007/978-3-031-23705-8_10. Adv Exp Med Biol. 2023. PMID: 37452942
Recently, the fourth edition of the World Health Organization (WHO) 2017 classified pituitary tumors focusing on histopathologic and molecular genetics features and introduced new entities like pituitary blastoma. Most of pituitary gland neoplasms occur sporadically …
Recently, the fourth edition of the World Health Organization (WHO) 2017 classified pituitary tumors focusing on histopathologic and molecul …
Imaging of pituitary tumors: an update with the 5th WHO Classifications-part 2. Neoplasms other than PitNET and tumor-mimicking lesions.
Tsukamoto T, Miki Y. Tsukamoto T, et al. Jpn J Radiol. 2023 Aug;41(8):808-829. doi: 10.1007/s11604-023-01407-0. Epub 2023 Mar 13. Jpn J Radiol. 2023. PMID: 36913010 Free PMC article. Review.
In this paper, we present the latest WHO classification of pituitary tumors (adamantinomatous craniopharyngioma, papillary craniopharyngioma, pituitary blastoma, pituicyte tumor family, tumors of pituitary origin other than those of the pituicyte tumor family, germi …
In this paper, we present the latest WHO classification of pituitary tumors (adamantinomatous craniopharyngioma, papillary craniopharyngioma …
Embryonal Tumors of the Central Nervous System: An Update.
Blessing MM, Alexandrescu S. Blessing MM, et al. Surg Pathol Clin. 2020 Jun;13(2):235-247. doi: 10.1016/j.path.2020.01.003. Epub 2020 Apr 7. Surg Pathol Clin. 2020. PMID: 32389264 Review.
Well-defined embryonal tumors include medulloblastoma, atypical teratoid/rhabdoid tumor, embryonal tumor with multilayered rosettes, C19MC-altered and embryonal tumor with multilayered rosettes, not otherwise specified, pineoblastoma, pituitary blastoma, CNS neurobl …
Well-defined embryonal tumors include medulloblastoma, atypical teratoid/rhabdoid tumor, embryonal tumor with multilayered rosettes, C19MC-a …
Primary Tumors of the Pituitary Gland: Radiologic-Pathologic Correlation.
Shih RY, Schroeder JW, Koeller KK. Shih RY, et al. Radiographics. 2021 Nov-Dec;41(7):2029-2046. doi: 10.1148/rg.2021200203. Epub 2021 Oct 1. Radiographics. 2021. PMID: 34597177
From a radiologic standpoint, microadenomas pose challenges for accurate detection and avoiding false-negative or false-positive results, while macroadenomas pose challenges from local mass effect on surrounding structures. Pituitary carcinoma and pituitary blastoma …
From a radiologic standpoint, microadenomas pose challenges for accurate detection and avoiding false-negative or false-positive results, wh …
16 results