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Quoted phrase not found in phrase index: "Platelet disorder, undefined"
Page 1
Predicting outcome in higher-risk myelodysplastic syndrome patients treated with azacitidine.
Bouchla A, Thomopoulos TP, Papageorgiou SG, Apostolopoulou C, Loucari C, Mpazani E, Pappa V. Bouchla A, et al. Epigenomics. 2021 Jul;13(14):1129-1143. doi: 10.2217/epi-2021-0124. Epub 2021 Jul 22. Epigenomics. 2021. PMID: 34291653 Review.
Lay abstract Myelodysplastic syndrome is a disorder in which patients have dysfunctional blood cells. The only chance of curing patients with high-risk myelodysplastic syndrome (HR-MDS) is allogeneic stem cell transplantation. ...However, 5-AZA has side effects that …
Lay abstract Myelodysplastic syndrome is a disorder in which patients have dysfunctional blood cells. The only chance of curin …
Polyphenols: Potential Use in the Prevention and Treatment of Cardiovascular Diseases.
Giglio RV, Patti AM, Cicero AFG, Lippi G, Rizzo M, Toth PP, Banach M. Giglio RV, et al. Curr Pharm Des. 2018;24(2):239-258. doi: 10.2174/1381612824666180130112652. Curr Pharm Des. 2018. PMID: 29384050 Review.
Many studies have demonstrated that polyphenols have also good effects on the vascular system by lowering blood pressure, improving endothelial function, increasing antioxidant defences, inhibiting platelet aggregation and low-density lipoprotein oxidation, and redu …
Many studies have demonstrated that polyphenols have also good effects on the vascular system by lowering blood pressure, improving e …
Coagulopathy in trauma patients: importance of thrombocyte function?
Davenport RA, Brohi K. Davenport RA, et al. Curr Opin Anaesthesiol. 2009 Apr;22(2):261-6. doi: 10.1097/ACO.0b013e328325a6d9. Curr Opin Anaesthesiol. 2009. PMID: 19390252 Review.
A pathophysiological role of platelets in this condition remains as yet undefined. This review examines our current knowledge of platelet function in haemostasis, possible mechanisms for aberrant activity in trauma and the role of platelet transfusions in exs …
A pathophysiological role of platelets in this condition remains as yet undefined. This review examines our current knowledge of p …
Von Willebrand's disease.
Ewenstein BM. Ewenstein BM. Annu Rev Med. 1997;48:525-42. doi: 10.1146/annurev.med.48.1.525. Annu Rev Med. 1997. PMID: 9046981 Review.
von Willebrand's disease (vWD) arises from abnormalities in von Willebrand factor (vWF), an adhesive glycoprotein uniquely involved in key aspects of both primary and secondary hemostasis. The current classification distinguishes disorders arising from partial (type 1) or …
von Willebrand's disease (vWD) arises from abnormalities in von Willebrand factor (vWF), an adhesive glycoprotein uniquely involved in key a …
Potential role of platelets in the pathogenesis of tumor metastasis.
Mehta P. Mehta P. Blood. 1984 Jan;63(1):55-63. Blood. 1984. PMID: 6360248 Free article. Review.
Certain tumor cell lines directly stimulate platelet activity, some by releasing platelet-aggregating material, a urea-extractable membrane component, others by release of cathepsin, and still others by undefined mechanisms. ...Lack of these platelet f …
Certain tumor cell lines directly stimulate platelet activity, some by releasing platelet-aggregating material, a urea-extract …
Neuraxial techniques in obstetric and non-obstetric patients with common bleeding diatheses.
Choi S, Brull R. Choi S, et al. Anesth Analg. 2009 Aug;109(2):648-60. doi: 10.1213/ane.0b013e3181ac13d1. Anesth Analg. 2009. PMID: 19608843 Review.
Among the 326 neuraxial techniques placed in the setting of ITP, 9 patients had platelet counts of <50 x 10(9) L(-1), 19 had a platelet counts of 50-75 x 10(9) L(-1), 204 had a platelet counts of 75-100 x 10(9) L(-1), and 94 had a platelet count mor …
Among the 326 neuraxial techniques placed in the setting of ITP, 9 patients had platelet counts of <50 x 10(9) L(-1), 19 had a …
Clinical, genetic, and therapeutic insights into systemic mast cell disease.
Tefferi A, Pardanani A. Tefferi A, et al. Curr Opin Hematol. 2004 Jan;11(1):58-64. doi: 10.1097/00062752-200401000-00009. Curr Opin Hematol. 2004. PMID: 14676628 Review.
RECENT FINDINGS: A series of laboratory investigations has revealed that mast cell disease is a clonal stem cell disorder, and at least two genes (c-kit and PDGFRA) with pathogenetically relevant mutations have been identified. ...SUMMARY: A partial molecular classificatio …
RECENT FINDINGS: A series of laboratory investigations has revealed that mast cell disease is a clonal stem cell disorder, and at lea …
Myeloid-derived suppressor cells in patients with myeloproliferative neoplasm.
Wang JC, Kundra A, Andrei M, Baptiste S, Chen C, Wong C, Sindhu H. Wang JC, et al. Leuk Res. 2016 Apr;43:39-43. doi: 10.1016/j.leukres.2016.02.004. Epub 2016 Feb 16. Leuk Res. 2016. PMID: 26943702 Clinical Trial.
MDSCs were studied in two cohorts: the first cohort was 55 patients including 16 primary myelofibrosis (PMF), 7 post-polycythemia vera (PV)-MF, 2 post-essential thrombocythemia (ET)-MF, 11 ET, 17 PV, 2 undefined MPN disorder, and 23 normal controls; the second cohor …
MDSCs were studied in two cohorts: the first cohort was 55 patients including 16 primary myelofibrosis (PMF), 7 post-polycythemia vera (PV)- …
Hematologic toxicities associated with mTOR inhibitors temsirolimus and everolimus in cancer patients: a systematic review and meta-analysis.
Xu J, Tian D. Xu J, et al. Curr Med Res Opin. 2014 Jan;30(1):67-74. doi: 10.1185/03007995.2013.844116. Epub 2013 Oct 4. Curr Med Res Opin. 2014. PMID: 24028709 Review.
Hematological toxicities have been reported with these drugs, but overall incidence and relative risk remains undefined. We perform an up-to-date meta-analysis to determine the incidence and risk of hematologic toxicities associated with mTOR inhibitors. ...Overall inciden …
Hematological toxicities have been reported with these drugs, but overall incidence and relative risk remains undefined. We perform a …
Platelet response to direct thrombin inhibitor or fondaparinux treatment in patients with suspected heparin-induced thrombocytopenia.
Pon TK, Mahajan A, Rosenberg A, Amin A, Shah D, Jenkins I, Gupta V, Hofmann H, Bejjani A, White R. Pon TK, et al. J Thromb Thrombolysis. 2018 May;45(4):536-542. doi: 10.1007/s11239-018-1646-x. J Thromb Thrombolysis. 2018. PMID: 29574610
However, the platelet response following discontinuation of heparin and initiation of a recommended alternative anticoagulant remains largely undefined and unstudied. ...The negative predictive value of no platelet rise was 75.5% (95% CI 0.61-0.86). A prompt …
However, the platelet response following discontinuation of heparin and initiation of a recommended alternative anticoagulant remains …
26 results