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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 1
1947 3
1948 3
1951 7
1952 19
1953 14
1954 16
1955 12
1956 10
1957 8
1958 7
1959 4
1964 7
1965 25
1966 42
1967 76
1968 85
1969 109
1970 125
1971 123
1972 129
1973 209
1974 199
1975 176
1976 162
1977 171
1978 150
1979 195
1980 175
1981 243
1982 233
1983 252
1984 318
1985 330
1986 304
1987 330
1988 331
1989 417
1990 425
1991 528
1992 513
1993 553
1994 545
1995 623
1996 665
1997 675
1998 654
1999 698
2000 776
2001 829
2002 861
2003 937
2004 1021
2005 1109
2006 1178
2007 1162
2008 1279
2009 1328
2010 1513
2011 1579
2012 1727
2013 1798
2014 1817
2015 1979
2016 2070
2017 2202
2018 2192
2019 2309
2020 7748
2021 3262
2022 2660
2023 2147
2024 789

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52,272 results

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Page 1
Antibiotics for hospital-acquired pneumonia in neonates and children.
Korang SK, Nava C, Mohana SP, Nygaard U, Jakobsen JC. Korang SK, et al. Cochrane Database Syst Rev. 2021 Nov 2;11(11):CD013864. doi: 10.1002/14651858.CD013864.pub2. Cochrane Database Syst Rev. 2021. PMID: 34727368 Free PMC article. Review.
SELECTION CRITERIA: We included randomised clinical trials comparing one antibiotic regimen with any other antibiotic regimen for hospital-acquired pneumonia in neonates and children. ...The current evidence is insufficient to support any antibiotic regimen b …
SELECTION CRITERIA: We included randomised clinical trials comparing one antibiotic regimen with any other antibiotic regimen …
Short-Course vs Long-Course Antibiotic Therapy for Children With Nonsevere Community-Acquired Pneumonia: A Systematic Review and Meta-analysis.
Li Q, Zhou Q, Florez ID, Mathew JL, Shang L, Zhang G, Tian X, Fu Z, Liu E, Luo Z, Chen Y. Li Q, et al. JAMA Pediatr. 2022 Dec 1;176(12):1199-1207. doi: 10.1001/jamapediatrics.2022.4123. JAMA Pediatr. 2022. PMID: 36374480 Free PMC article.
DATA SOURCES: MEDLINE, Embase, Web of Science, the Cochrane Library, and 3 Chinese databases from inception to March 31, 2022, as well as clinical trial registries and Google.com. STUDY SELECTION: Randomized clinical trials comparing a shorter- vs long …
DATA SOURCES: MEDLINE, Embase, Web of Science, the Cochrane Library, and 3 Chinese databases from inception to March 31, 2022, as well as …
Transfusion thresholds for guiding red blood cell transfusion.
Carson JL, Stanworth SJ, Dennis JA, Trivella M, Roubinian N, Fergusson DA, Triulzi D, Dorée C, Hébert PC. Carson JL, et al. Cochrane Database Syst Rev. 2021 Dec 21;12(12):CD002042. doi: 10.1002/14651858.CD002042.pub5. Cochrane Database Syst Rev. 2021. PMID: 34932836 Free PMC article. Review.
OBJECTIVES: The aim of this review update was to compare 30-day mortality and other clinical outcomes for participants randomised to restrictive versus liberal red blood cell (RBC) transfusion thresholds (triggers) for all clinical conditions. ...We conducted …
OBJECTIVES: The aim of this review update was to compare 30-day mortality and other clinical outcomes for participants randomised …
Discontinuing beta-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-controlled, non-inferiority trial.
Dinh A, Ropers J, Duran C, Davido B, Deconinck L, Matt M, Senard O, Lagrange A, Makhloufi S, Mellon G, de Lastours V, Bouchand F, Mathieu E, Kahn JE, Rouveix E, Grenet J, Dumoulin J, Chinet T, Pépin M, Delcey V, Diamantis S, Benhamou D, Vitrat V, Dombret MC, Renaud B, Perronne C, Claessens YE, Labarère J, Bedos JP, Aegerter P, Crémieux AC; Pneumonia Short Treatment (PTC) Study Group. Dinh A, et al. Lancet. 2021 Mar 27;397(10280):1195-1203. doi: 10.1016/S0140-6736(21)00313-5. Lancet. 2021. PMID: 33773631 Clinical Trial.
We aimed to assess the need for an additional 5-day course of beta-lactam therapy among patients with community-acquired pneumonia who were stable after 3 days of treatment. METHODS: We did this double-blind, randomised, placebo-controlled, non-inferiority trial …
We aimed to assess the need for an additional 5-day course of beta-lactam therapy among patients with community-acquired pneumonia wh …
Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial.
Blum CA, Nigro N, Briel M, Schuetz P, Ullmer E, Suter-Widmer I, Winzeler B, Bingisser R, Elsaesser H, Drozdov D, Arici B, Urwyler SA, Refardt J, Tarr P, Wirz S, Thomann R, Baumgartner C, Duplain H, Burki D, Zimmerli W, Rodondi N, Mueller B, Christ-Crain M. Blum CA, et al. Lancet. 2015 Apr 18;385(9977):1511-8. doi: 10.1016/S0140-6736(14)62447-8. Epub 2015 Jan 19. Lancet. 2015. PMID: 25608756 Clinical Trial.
BACKGROUND: Clinical trials yielded conflicting data about the benefit of adding systemic corticosteroids for treatment of community-acquired pneumonia. ...METHODS: In this double-blind, multicentre, randomised, placebo-controlled trial, we recruited p …
BACKGROUND: Clinical trials yielded conflicting data about the benefit of adding systemic corticosteroids for treatment of community- …
Ceftaroline.
Soriano A. Soriano A. Rev Esp Quimioter. 2021 Sep;34 Suppl 1(Suppl1):29-31. doi: 10.37201/req/s01.08.2021. Epub 2021 Sep 30. Rev Esp Quimioter. 2021. PMID: 34598420 Free PMC article. Review.
Community-acquired pneumonia (CAP) is one of the leading causes of admission to emergency departments. Ceftaroline is a fifth-generation cephalosporin with a potent In vitro activity against Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus, the th …
Community-acquired pneumonia (CAP) is one of the leading causes of admission to emergency departments. Ceftaroline is a fifth-generat …
Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia: a systematic review and meta-analysis of randomized controlled trials.
Wu JY, Tsai YW, Hsu WH, Liu TH, Huang PY, Chuang MH, Liu MY, Lai CC. Wu JY, et al. Crit Care. 2023 Jul 8;27(1):274. doi: 10.1186/s13054-023-04561-z. Crit Care. 2023. PMID: 37422686 Free PMC article.
BACKGROUND: This systematic review and meta-analysis aimed to investigate the clinical efficacy and safety of systemic corticosteroids in the treatment of patients with severe community-acquired pneumonia (sCAP). METHODS: A comprehensive search was conducted using t …
BACKGROUND: This systematic review and meta-analysis aimed to investigate the clinical efficacy and safety of systemic corticosteroid …
Inhaled amikacin versus placebo to prevent ventilator-associated pneumonia: the AMIKINHAL double-blind multicentre randomised controlled trial protocol.
Tavernier E, Barbier F, Meziani F, Quenot JP, Herbrecht JE, Landais M, Roux D, Seguin P, Schnell D, Veinstein A, Veber B, Lasocki S, Lu Q, Beduneau G, Ferrandiere M, Dahyot-Fizelier C, Plantefeve G, Nay MA, Merdji H, Andreu P, Vecellio L, Muller G, Cabrera M, Le Pennec D, Respaud R, Lanotte P, Gregoire N, Leclerc M, Helms J, Boulain T, Lacherade JC, Ehrmann S; REVA network and the CRICS-TRIGGESEP F-CRIN network. Tavernier E, et al. BMJ Open. 2021 Sep 14;11(9):e048591. doi: 10.1136/bmjopen-2020-048591. BMJ Open. 2021. PMID: 34521664 Free PMC article.
METHODS AND ANALYSIS: Academic, investigator-initiated, parallel two group arms, double-blind, multicentre superiority randomised controlled trial. Patients invasively ventilated more than 3 days will be randomised to receive 20 mg/kg inhaled amikacin daily f …
METHODS AND ANALYSIS: Academic, investigator-initiated, parallel two group arms, double-blind, multicentre superiority randomised con …
Corticosteroids for pneumonia.
Chen Y, Li K, Pu H, Wu T. Chen Y, et al. Cochrane Database Syst Rev. 2011 Mar 16;(3):CD007720. doi: 10.1002/14651858.CD007720.pub2. Cochrane Database Syst Rev. 2011. PMID: 21412908 Updated. Review.
SELECTION CRITERIA: Randomised controlled trials (RCTs) assessing the effectiveness of corticosteroids for pneumonia. DATA COLLECTION AND ANALYSIS: Three review authors selected studies. We telephoned the trial authors to confirm the randomisation meth …
SELECTION CRITERIA: Randomised controlled trials (RCTs) assessing the effectiveness of corticosteroids for pneumonia. DATA COL …
Emerging antibiotics for community-acquired pneumonia.
Liapikou A, Cilloniz C, Palomeque A, Torres T. Liapikou A, et al. Expert Opin Emerg Drugs. 2019 Dec;24(4):221-231. doi: 10.1080/14728214.2019.1685494. Epub 2019 Nov 1. Expert Opin Emerg Drugs. 2019. PMID: 31657962 Free article. Review.
Increasing antibiotic resistance among the common bacterial pathogens associated with community-acquired pneumonia, especially Streptococcus pneumoniae and staphylococci, has made its empirical treatment increasingly problematic, highlighting the need for effective antibio …
Increasing antibiotic resistance among the common bacterial pathogens associated with community-acquired pneumonia, especially Strept …
52,272 results
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