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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2003 1
2005 2
2006 1
2007 1
2009 3
2010 2
2011 6
2013 1
2014 1
2016 1
2017 2
2018 1
2019 1
2024 0

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21 results

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Page 1
Genetic alterations and protein expression of HER2 and chromosome 17 polysomy in breast cancer.
Zhu X, Lu Y, Lu H, Yang W, Tu X, Cai X, Zhou X. Zhu X, et al. Hum Pathol. 2011 Oct;42(10):1499-504. doi: 10.1016/j.humpath.2010.04.023. Epub 2011 Jun 14. Hum Pathol. 2011. PMID: 21676436

The HER2 amplification occurred more likely in cases with higher immunohistochemistry scores (P < .001), and polysomy 17 was observed in 28.3% of cases, but more frequently in the HER2 amplification subgroup (33.3%) than in the HER2 nonamplification subgroup (20.

…

The HER2 amplification occurred more likely in cases with higher immunohistochemistry scores (P < .001), and polysomy 17 wa

…
Status of HER2 amplification, polysomy 17 and histopathological features of 425 Pakistani breast cancer patients.
Moatter T, Aban M, Iqbal W, Azam I, Pervaiz A, Siddiqui F, Murad F, Pervez S. Moatter T, et al. Asian Pac J Cancer Prev. 2011;12(11):3069-73. Asian Pac J Cancer Prev. 2011. PMID: 22393991 Free article.
Association between IHC and FISH in both subsets was calculated by amplification ratio including polysomy 17. Out of 425 specimens, 128 (30%) were positive for HER2 amplification by FISH test, whereas only 78 (24%) tumors with 2+ expression showed amplification. ... …
Association between IHC and FISH in both subsets was calculated by amplification ratio including polysomy 17. Out of 425 speci …
HER2 and TOP2A Gene Amplification and Protein Expression in Upper Tract Urothelial Carcinomas.
Aumayr K, Klatte T, Neudert B, Birner P, Shariat S, Schmidinger M, Susani M, Haitel A. Aumayr K, et al. Pathol Oncol Res. 2018 Jul;24(3):575-581. doi: 10.1007/s12253-017-0260-0. Epub 2017 Jul 28. Pathol Oncol Res. 2018. PMID: 28755093 Free article.
HER2 protein expression was observed in 27/81 (33%) cases, of which 8 cases exhibited amplification of HER2. One of them had an additional polysomy 17, whereas 6/67 HER2 non-amplified cases revealed a polysomy 17. ...In univariate analyses HER2 IHC pos …
HER2 protein expression was observed in 27/81 (33%) cases, of which 8 cases exhibited amplification of HER2. One of them had an additional …
Impact of polysomy 17 on HER2 testing of invasive breast cancer patients.
Liu Y, Ma L, Liu D, Yang Z, Yang C, Hu Z, Chen W, Yang Z, Chen S, Zhang Z. Liu Y, et al. Int J Clin Exp Pathol. 2013 Dec 15;7(1):163-73. eCollection 2014. Int J Clin Exp Pathol. 2013. PMID: 24427336 Free PMC article.
The distribution of clinicopathologic parameters of Polysomy 17 tumors was more similar to HER2 negative than HER2 positive tumors. ...Polysomy 17 cannot be an independent predictive factor for HER2 gene amplification or protein overexpression....
The distribution of clinicopathologic parameters of Polysomy 17 tumors was more similar to HER2 negative than HER2 positive tu …
FISH and HER2/neu equivocal immunohistochemistry in breast carcinoma.
Patil Okaly GV, Panwar D, Lingappa KB, Kumari P, Anand A, Kumar P, Chikkalingaiah MH, Kumar RV. Patil Okaly GV, et al. Indian J Cancer. 2019 Apr-Jun;56(2):119-123. doi: 10.4103/ijc.IJC_333_18. Indian J Cancer. 2019. PMID: 31062729 Free article.
Ten cases were reported as equivocal even on FISH (ASCO/CAP 2013 guidelines). Polysomy 17 was noted in 55 cases (41%), of which 26 patients were50 years and 29 patients were >50 years of age. ...
Ten cases were reported as equivocal even on FISH (ASCO/CAP 2013 guidelines). Polysomy 17 was noted in 55 cases (41%), of whic …
Role of Genomic Alterations in HER2 Positive Breast Carcinoma: Focus on Susceptibility and Trastuzumab-therapy.
Singla H, Kalra S, Kheterpal P, Kumar V, Munshi A. Singla H, et al. Curr Cancer Drug Targets. 2017;17(4):344-356. doi: 10.2174/1568009616666161216094026. Curr Cancer Drug Targets. 2017. PMID: 27993117 Review.
HER2 positive is a distinct breast cancer subtype, on account of its unique biology and physiological behavior. RESULTS: Amplification of HER2 oncogene/polysomy 17 leads to HER2 overexpression that is a significant causal implication in HER2 positive breast cancer. …
HER2 positive is a distinct breast cancer subtype, on account of its unique biology and physiological behavior. RESULTS: Amplification of HE …
Her-2 immunohistochemical expression in oral squamous cell carcinomas is associated with polysomy of chromosome 17, not Her-2 amplification.
Papavasileiou D, Tosios K, Christopoulos P, Goutas N, Vlachodimitropoulos D. Papavasileiou D, et al. Head Neck Pathol. 2009 Dec;3(4):263-70. doi: 10.1007/s12105-009-0134-1. Epub 2009 Aug 22. Head Neck Pathol. 2009. PMID: 20596843 Free PMC article.
Positive cases were analyzed by chromogenic in situ hybridisation (CISH) to access Her-2 status. The association between polysomy 17 and Her-2 expression was checked by Fisher's exact test. ...There was a statistically significant correlation between intensity of th …
Positive cases were analyzed by chromogenic in situ hybridisation (CISH) to access Her-2 status. The association between polysomy …
Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situ hybridization and immunohistochemistry.
Salido M, Tusquets I, Corominas JM, Suarez M, Espinet B, Corzo C, Bellet M, Fabregat X, Serrano S, Solé F. Salido M, et al. Breast Cancer Res. 2005;7(2):R267-73. doi: 10.1186/bcr996. Epub 2005 Jan 26. Breast Cancer Res. 2005. PMID: 15743507 Free PMC article.
RESULTS: We found 13% of cases presenting polysomy, and three cases presented monosomy 17 (2%). According to the status of the ERBB2 gene, instances of polysomy 17 were more frequently observed in non-amplified cases than in FISH-amplified cases, suggesting that the …
RESULTS: We found 13% of cases presenting polysomy, and three cases presented monosomy 17 (2%). According to the status of the ERBB2 gene, i …
Expression and amplification of Topoisomerase-2α in type 1 and type 2 papillary renal cell carcinomas and its correlation with HER2/neu amplification.
Duzcan F, Duzcan SE, Sen S, Yorukoglu K, Caner V, Sen Turk N, Cetin GO, Kelten C, Tuna B, Sarsik B, Tepeli E. Duzcan F, et al. Pathol Oncol Res. 2011 Sep;17(3):697-703. doi: 10.1007/s12253-011-9372-0. Epub 2011 Apr 2. Pathol Oncol Res. 2011. PMID: 21461646 Free article.
A multicolor FISH probe was used to define both amplification of HER2/neu and TOP2alpha genes, and polysomy 17. The ratio of cells expressing TOP2alpha in type 1 and type 2 papillary RCC were 24.29% and 6.89%, respectively. ...
A multicolor FISH probe was used to define both amplification of HER2/neu and TOP2alpha genes, and polysomy 17. The ratio of c …
21 results