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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 4
1947 5
1948 5
1949 1
1950 5
1951 3
1952 4
1953 9
1954 3
1955 6
1956 4
1957 5
1958 6
1959 4
1960 1
1961 9
1962 5
1963 12
1964 16
1965 7
1973 1
1974 3
1975 14
1976 13
1977 11
1978 17
1979 12
1980 16
1981 7
1982 18
1983 14
1984 17
1985 20
1986 32
1987 36
1988 26
1989 28
1990 26
1991 32
1992 26
1993 14
1994 15
1995 25
1996 42
1997 39
1998 20
1999 45
2000 61
2001 47
2002 37
2003 57
2004 76
2005 49
2006 73
2007 74
2008 64
2009 65
2010 76
2011 92
2012 88
2013 90
2014 109
2015 94
2016 65
2017 69
2018 59
2019 35
2020 1
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1,937 results
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Page 1
Preservatives in glaucoma medication.
Steven DW, et al. Br J Ophthalmol 2018 - Review. PMID 29973365 Free PMC article.
Benzalkonium chloride (BAK) remains the most commonly used preservative but there is a trend towards the use of preservative-free (PF) drops for glaucoma, although at a higher price. ...However, there have been very few randomised controlled trials that compare the same medication with and without BAK preservative. ...
Benzalkonium chloride (BAK) remains the most commonly used preservative but there is a trend towards the use of preservative-f …
Cosmetics Preservation: A Review on Present Strategies.
Halla N, et al. Molecules 2018 - Review. PMID 29958439 Free PMC article.
Current validation of a preservation system follow the application of good manufacturing practices (GMPs), the control of the raw material, and the verification of the preservative effect by suitable methodologies, including the challenge test. ...Preservatives act on several cell targets; however, they might present toxic effects to the consumer. Indeed, their use at high concentrations is more effective from the preservation viewpoint being, however, toxic for the consumer, whereas at low concentrations microbial resistance can develop....
Current validation of a preservation system follow the application of good manufacturing practices (GMPs), the control of the raw mat …
Parabens. From environmental studies to human health
Błędzka D, et al. Environ Int 2014 - Review. PMID 24657492
Parabens are a group of substances commonly employed as preservatives, mainly in personal care products, pharmaceuticals and food. ...
Parabens are a group of substances commonly employed as preservatives, mainly in personal care products, pharmaceuticals and f …
Microbial Stability of Pharmaceutical and Cosmetic Products.
Dao H, et al. AAPS PharmSciTech 2018 - Review. PMID 29019083
This review gives a brief overview about microbial contamination in pharmaceutical products. We discuss the distribution and potential sources of microorganisms in different areas, ranging from manufacturing sites, pharmacy stores, hospitals, to the post-market phase. ...The most common method for countering microbial contamination is the use of preservatives. We review some frequently used preservatives, and we describe the mechanisms by which microorganisms develop resistance to these preservatives. ...
This review gives a brief overview about microbial contamination in pharmaceutical products. We discuss the distribution and potentia …
Benzalkonium chloride and glaucoma
Rasmussen CA, et al. J Ocul Pharmacol Ther 2014 - Review. PMID 24205938 Free PMC article.
Benzalkonium chloride (BAK) is the most common preservative in glaucoma medications. BAK has been detected in the trabecular meshwork (TM), corneal endothelium, lens, and retina after topical drop installation and may accumulate in those tissues. ...
Benzalkonium chloride (BAK) is the most common preservative in glaucoma medications. BAK has been detected in the trabecular meshwork …
Pulmonary Toxicity of Benzalkonium Chloride
Johnson NF. J Aerosol Med Pulm Drug Deliv 2018 - Review. PMID 28683210
The available toxicity data of benzalkonium chloride (BKC) clearly shows that it is toxic; however, the weight of evidence favors the view that at doses encountered in nasally and orally inhaled pharmaceutical preparations it is well tolerated. ...
The available toxicity data of benzalkonium chloride (BKC) clearly shows that it is toxic; however, the weight of evidence favors the view t …
Low-dose Thimerosal in pediatric vaccines: Adverse effects in perspective
Dórea JG. Environ Res 2017 - Review. PMID 27816865
It is claimed that the continued use of Thimerosal in the less-developed countries is due to the cost to change to another preservative, such as 2-phenoxyethanol. ...
It is claimed that the continued use of Thimerosal in the less-developed countries is due to the cost to change to another preservative
1,937 results
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