Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1995 1
1997 1
1998 1
1999 2
2001 1
2006 1
2008 2
2009 2
2011 2
2013 2
2014 2
2016 1
2017 2
2018 1
2019 3
2020 2
2021 3
2022 2
2023 4
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

32 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Prolonged need of intravenous antibiotic therapy"
Page 1
Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative Review.
Spellberg B, Chambers HF, Musher DM, Walsh TL, Bayer AS. Spellberg B, et al. JAMA Intern Med. 2020 May 1;180(5):769-777. doi: 10.1001/jamainternmed.2020.0555. JAMA Intern Med. 2020. PMID: 32227127 Free PMC article. Review.
Accordingly, recent studies of oral step-down antibiotic treatment have stimulated a reevaluation of the need for intravenous-only therapy for IE. ...The search identified 21 observational studies evaluating the effectiveness of oral antibiot …
Accordingly, recent studies of oral step-down antibiotic treatment have stimulated a reevaluation of the need for intraveno …
Safety of prolonged outpatient courses of intravenous antibiotics: a prospective cohort study.
Browning S, Loewenthal MR, Freelander I, Dobson PM, Schneider K, Davis JS. Browning S, et al. Clin Microbiol Infect. 2022 Jun;28(6):832-837. doi: 10.1016/j.cmi.2021.12.020. Epub 2022 Jan 8. Clin Microbiol Infect. 2022. PMID: 35017063 Free article.
OBJECTIVES: The perceived need for prolonged intravenous antibiotic courses has become a major driver behind the growth of outpatient parenteral antimicrobial therapy (OPAT) services. ...Adults admitted to the service between 1 June 2009 and 30 …
OBJECTIVES: The perceived need for prolonged intravenous antibiotic courses has become a major driver behind the …
Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal.
Osthoff M, Siegemund M, Balestra G, Abdul-Aziz MH, Roberts JA. Osthoff M, et al. Swiss Med Wkly. 2016 Oct 10;146:w14368. doi: 10.4414/smw.2016.14368. eCollection 2016. Swiss Med Wkly. 2016. PMID: 27731492 Free article. Review.
Prolonged infusion of beta-lactam antibiotics as either extended (over at least 2 hours) or continuous infusion is increasingly applied in intensive care units around the world in an attempt to optimise treatment with this most commonly used class of antibiotics …
Prolonged infusion of beta-lactam antibiotics as either extended (over at least 2 hours) or continuous infusion is increasingl …
Prevalence and predictors of prolonged length of stay among patients admitted under general internal medicine in a tertiary government hospital in Manila, Philippines: a retrospective cross-sectional study.
Besa JJV, Masamayor EMI, Tamondong-Lachica DR, Palileo-Villanueva LM. Besa JJV, et al. BMC Health Serv Res. 2023 Jan 18;23(1):50. doi: 10.1186/s12913-022-08885-4. BMC Health Serv Res. 2023. PMID: 36653777 Free PMC article. Review.
RESULTS: The prevalence of PLOS is 19.17% (95% CI 15.54, 23.42). Positive predictors include being partially dependent on admission (aOR 2.61, 95% CI 0.99, 6.86), more co-managing services (aOR 1.26, 95% CI 1.06, 1.50), and longer duration of intravenous antibiot …
RESULTS: The prevalence of PLOS is 19.17% (95% CI 15.54, 23.42). Positive predictors include being partially dependent on admission ( …
Clinical and pharmacokinetic/dynamic outcomes of prolonged infusions of beta-lactam antimicrobials: An overview of systematic reviews.
Thabet P, Joshi A, MacDonald E, Hutton B, Cheng W, Stevens A, Kanji S. Thabet P, et al. PLoS One. 2021 Jan 22;16(1):e0244966. doi: 10.1371/journal.pone.0244966. eCollection 2021. PLoS One. 2021. PMID: 33481817 Free PMC article.
Evidence of mortality and clinical cure benefit was greater among critically ill patients when compared to less sick patients and lower in randomized controlled trials when compared with observational studies. CONCLUSIONS: Findings from our review demonstrate a consistent …
Evidence of mortality and clinical cure benefit was greater among critically ill patients when compared to less sick patients and lower in r …
Prolonged infusion versus intermittent boluses of beta-lactam antibiotics for treatment of acute infections: a meta-analysis.
Teo J, Liew Y, Lee W, Kwa AL. Teo J, et al. Int J Antimicrob Agents. 2014 May;43(5):403-11. doi: 10.1016/j.ijantimicag.2014.01.027. Epub 2014 Mar 1. Int J Antimicrob Agents. 2014. PMID: 24657044 Review.
A search of PubMed, EMBASE and The Cochrane Library for randomised controlled trials (RCTs) and observational studies comparing prolonged infusion with intermittent bolus administration of the same antibiotic in hospitalised adult patients was conducted. ...S …
A search of PubMed, EMBASE and The Cochrane Library for randomised controlled trials (RCTs) and observational studies comparing pr …
Severe ulcerative colitis: at what point should we define resistance to steroids?
Esteve M, Gisbert JP. Esteve M, et al. World J Gastroenterol. 2008 Sep 28;14(36):5504-7. doi: 10.3748/wjg.14.5504. World J Gastroenterol. 2008. PMID: 18810766 Free PMC article. Review.
The mortality related to severe attacks of ulcerative colitis has decreased dramatically, to less than 1%, in experienced centers, due to the appropriate use of intensive therapeutic measures (intravenous steroids, fluids and electrolytes, artificial nutritional support, …
The mortality related to severe attacks of ulcerative colitis has decreased dramatically, to less than 1%, in experienced centers, due to th …
Revisiting Beta-lactams - PK/PD improves dosing of old antibiotics.
MacGowan A. MacGowan A. Curr Opin Pharmacol. 2011 Oct;11(5):470-6. doi: 10.1016/j.coph.2011.07.006. Epub 2011 Aug 19. Curr Opin Pharmacol. 2011. PMID: 21862409 Review.
Pre-clinical pharmacokinetic-pharmacodynamic assessments indicate Beta-lactam antibiotics have time-dependent killing, variable persistent antibiotic effects and that free drug T>MIC is the dominant pharmacodynamic index. Prolonged or continuous infusion …
Pre-clinical pharmacokinetic-pharmacodynamic assessments indicate Beta-lactam antibiotics have time-dependent killing, variable persi …
Bacterial meningitis in children: critical care needs.
Singhi S, Singhi P, Baranwal AK. Singhi S, et al. Indian J Pediatr. 2001 Aug;68(8):737-47. doi: 10.1007/BF03191900. Indian J Pediatr. 2001. PMID: 11563252 Review.

Attention should first be directed toward basic ABCs of life-support. Children with Glasgow Coma Scale (GSC) score < 8 need intubation and supplemental oxygen. Antibiotics should be started, even without LP (contraindicated if focal neuro-deficit, papilled

…

Attention should first be directed toward basic ABCs of life-support. Children with Glasgow Coma Scale (GSC) score < 8 need

…
Telavancin: a new lipoglycopeptide for gram-positive infections.
Smith WJ, Drew RH. Smith WJ, et al. Drugs Today (Barc). 2009 Mar;45(3):159-73. doi: 10.1358/dot.2009.45.3.1343792. Drugs Today (Barc). 2009. PMID: 19436839 Review.
The resulting activity in vitro is rapidly bactericidal and concentration dependent, with the ratio of area under the time concentration curve to minimum inhibitory concentration (AUC/MIC) as the best predictor of activity in animal models to date. In humans, telavancin ex …
The resulting activity in vitro is rapidly bactericidal and concentration dependent, with the ratio of area under the time concentration cur …
32 results