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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1978 7
1979 30
1980 40
1981 42
1982 39
1983 40
1984 47
1985 29
1986 51
1987 36
1988 41
1989 32
1990 34
1991 27
1992 28
1993 23
1994 12
1995 26
1996 8
1997 21
1998 15
1999 23
2000 20
2001 20
2002 13
2003 17
2004 8
2005 16
2006 8
2007 9
2008 7
2009 13
2010 5
2011 8
2012 7
2013 10
2014 7
2015 5
2016 6
2017 2
2018 4
2019 4
2020 3
2021 3
2022 3
2023 2
2024 1

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833 results

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Page 1
The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice.
Shynlova O, Nadeem L, Dorogin A, Mesiano S, Lye SJ. Shynlova O, et al. Am J Obstet Gynecol. 2022 Feb;226(2):249.e1-249.e21. doi: 10.1016/j.ajog.2021.08.013. Epub 2021 Aug 19. Am J Obstet Gynecol. 2022. PMID: 34418351 Free PMC article.
STUDY DESIGN: In the term labor mouse model, promegestone (0.2 mg/dam) or a vehicle were administered subcutaneously in timed-pregnant CD-1 mice at gestational days 15, 16, and 17 (term gestational days, 19.5). ...Promegestone did not prevent bacterial-endotoxin-ind …
STUDY DESIGN: In the term labor mouse model, promegestone (0.2 mg/dam) or a vehicle were administered subcutaneously in timed-pregnan …
Double-blind trial of promegestone (R 5020) and lynestrenol in the treatment of benign breast disease.
Uzan S, Denis C, Pomi V, Varin C. Uzan S, et al. Eur J Obstet Gynecol Reprod Biol. 1992 Feb 28;43(3):219-27. doi: 10.1016/0028-2243(92)90177-z. Eur J Obstet Gynecol Reprod Biol. 1992. PMID: 1563574 Clinical Trial.
Clinical tolerance was rated good or excellent for 73.9% of the women on 1 mg promegestone and for 59.5% of the women on 0.500 mg promegestone, compared to 66.7% of the women on lynestrenol. No statistically significant difference was observed, neither between lynes …
Clinical tolerance was rated good or excellent for 73.9% of the women on 1 mg promegestone and for 59.5% of the women on 0.500 mg …
The steroid promegestone is a noncompetitive antagonist of the Torpedo nicotinic acetylcholine receptor that interacts with the lipid-protein interface.
Blanton MP, Xie Y, Dangott LJ, Cohen JB. Blanton MP, et al. Mol Pharmacol. 1999 Feb;55(2):269-78. doi: 10.1124/mol.55.2.269. Mol Pharmacol. 1999. PMID: 9927618
Promegestone reversibly inhibited ACh-induced currents of Torpedo AChRs expressed in Xenopus oocytes. Between 1-30 microM promegestone produced a concentration-dependent enhancement of the equilibrium binding affinity of [3H]ACh to Torpedo AChR-rich membranes. ...
Promegestone reversibly inhibited ACh-induced currents of Torpedo AChRs expressed in Xenopus oocytes. Between 1-30 microM promeges …
Progesterone and promegestone stimulate human bone cell proliferation and insulin-like growth factor-2 production.
Tremollieres FA, Strong DD, Baylink DJ, Mohan S. Tremollieres FA, et al. Acta Endocrinol (Copenh). 1992 Apr;126(4):329-37. doi: 10.1530/acta.0.1260329. Acta Endocrinol (Copenh). 1992. PMID: 1375800
While no significant changes in IGF-1 levels were found in the conditioned media of progesterone and promegestone treated cultures, progesterone and promegestone at the concentration of 5 nmol/l significantly increased IGF-2 levels 2.4 and 1.5-fold respectively, at …
While no significant changes in IGF-1 levels were found in the conditioned media of progesterone and promegestone treated cultures, p …
[Promegestone, a new progestin].
Raynaud JP, Ojasoo T. Raynaud JP, et al. J Gynecol Obstet Biol Reprod (Paris). 1983;12(7):697-710. J Gynecol Obstet Biol Reprod (Paris). 1983. PMID: 6366037 Clinical Trial. French.
The biological activities of promegestone (R 5020), used world-wide as a radioligand for the progestin receptor, are described. Promegestone is a potent progestin devoid of androgenic side-effects and has marked anti-estrogenic activity. ...
The biological activities of promegestone (R 5020), used world-wide as a radioligand for the progestin receptor, are described. Pr …
Effect of the progestagen R5020 (promegestone) and of progesterone on the uptake and on the transformation of estrone sulfate in the MCF-7 and T-47d human mammary cancer cells: correlation with progesterone receptor levels.
Pasqualini JR, Varin C, Nguyen BL. Pasqualini JR, et al. Cancer Lett. 1992 Sep 14;66(1):55-60. doi: 10.1016/0304-3835(92)90280-9. Cancer Lett. 1992. PMID: 1451096
In the present study we have explored the actions of the progestagen R5020 (Promegestone: 17 alpha, 21-dimethyl-19-nor-pregna-4, 9-diene-3,20-dione) and progesterone on the uptake of [3H]estrone sulfate ([3H]E1S) and its conversion to estradiol (E2) by two hormone-dependen …
In the present study we have explored the actions of the progestagen R5020 (Promegestone: 17 alpha, 21-dimethyl-19-nor-pregna-4, 9-di …
Interactions of oestradiol benzoate and promegestone upon basal and TRH-induced prolactin secretion in postmenopausal women.
Joseph PJ, Couzinet B, Brailly S, Rigaud C, Raynaud JP, Schaison G. Joseph PJ, et al. Clin Endocrinol (Oxf). 1986 May;24(5):497-503. doi: 10.1111/j.1365-2265.1986.tb03278.x. Clin Endocrinol (Oxf). 1986. PMID: 3098454
In response to EB treatment serum PRL levels increased from 6.1 +/- 0.9 ng/ml to 22.9 +/- 3.4 ng/ml. With the addition of promegestone, the increase in PRL, from 6.7 +/- 1.3 ng/ml to 13.8 +/- 2.5 ng/ml, was significantly diminished (P less than 0.001). ...These data sugges …
In response to EB treatment serum PRL levels increased from 6.1 +/- 0.9 ng/ml to 22.9 +/- 3.4 ng/ml. With the addition of promegestone …
Effect of 16 beta-ethyl-17 beta-hydroxy-4-estren-3-one (TSAA-291) on the binding of promegestone (R5020) and methyltrienolone (R1881) to hyperplastic and neoplastic human prostate.
Bashirelahi N, Ganesan S, Ekiko DB, Young JD Jr, Shida K, Yamanaka H, Takahashi E. Bashirelahi N, et al. J Steroid Biochem. 1986 Sep;25(3):367-74. doi: 10.1016/0022-4731(86)90249-9. J Steroid Biochem. 1986. PMID: 2430141
The effect of a synthetic steroidal compound TSAA-291 (16 beta-ethyl-17 beta-hydroxy-4-estren-3-one) on the binding of methyltrienolone (R1881) and promegestone (R5020) to hyperplastic and neoplastic human prostate was investigated. ...Glycerol density gradient analysis re …
The effect of a synthetic steroidal compound TSAA-291 (16 beta-ethyl-17 beta-hydroxy-4-estren-3-one) on the binding of methyltrienolone (R18 …
Effects of estradiol and promegestone on human breast cell cultures. An ultrastructural study.
Chomette G, Auriol M, Tranbaloc P, Gompel A, Malet C, Kuttenn F. Chomette G, et al. Pathol Res Pract. 1986 Jun;181(3):273-9. doi: 10.1016/S0344-0338(86)80103-0. Pathol Res Pract. 1986. PMID: 3748873
Effects of estradiol (E2) and promegestone (R 5020) were tested on primary cultures of epithelial human breast cells prepared from surgical specimens of reduction mammoplasty. ...
Effects of estradiol (E2) and promegestone (R 5020) were tested on primary cultures of epithelial human breast cells prepared from su …
833 results