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Year Number of Results
1952 1
1975 1
1979 1
1982 1
1984 2
1985 1
1988 1
1990 1
1992 1
1993 2
1994 3
1995 1
1996 2
1997 1
1998 2
1999 7
2000 10
2001 7
2002 10
2003 11
2004 11
2005 15
2006 24
2007 21
2008 21
2009 43
2010 38
2011 51
2012 43
2013 41
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2015 58
2016 48
2017 59
2018 43
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2020 46
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2023 39
2024 12

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798 results

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Quoted phrase not found in phrase index: "Pulmonary disease, chronic obstructive, susceptibility to"
Page 1
Susceptibility to exacerbation in chronic obstructive pulmonary disease.
Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, Calverley P, Rennard S, Wouters EF, Wedzicha JA; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Hurst JR, et al. N Engl J Med. 2010 Sep 16;363(12):1128-38. doi: 10.1056/NEJMoa0909883. N Engl J Med. 2010. PMID: 20843247 Free article.
BACKGROUND: Although we know that exacerbations are key events in chronic obstructive pulmonary disease (COPD), our understanding of their frequency, determinants, and effects is incomplete. In a large observational cohort, we tested the hypothe …
BACKGROUND: Although we know that exacerbations are key events in chronic obstructive pulmonary disease (COPD), …
Inflammatory endotypes in COPD.
Barnes PJ. Barnes PJ. Allergy. 2019 Jul;74(7):1249-1256. doi: 10.1111/all.13760. Epub 2019 Mar 31. Allergy. 2019. PMID: 30834543 Review.
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is poorly treated by current therapies as it has proved difficult to treat the underlying inflammation, which is largely corticosteroid-resistant in most patients. ...Mo …
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is poorly treated by current …
Sex and Gender Differences in Lung Disease.
Silveyra P, Fuentes N, Rodriguez Bauza DE. Silveyra P, et al. Adv Exp Med Biol. 2021;1304:227-258. doi: 10.1007/978-3-030-68748-9_14. Adv Exp Med Biol. 2021. PMID: 34019273 Free PMC article.
In this chapter, we describe the epidemiology of sex differences in respiratory diseases including neonatal lung disease (respiratory distress syndrome, bronchopulmonary dysplasia) and pediatric and adult disease (including asthma, cystic fibrosis, idiopathic pul …
In this chapter, we describe the epidemiology of sex differences in respiratory diseases including neonatal lung disease (respiratory …
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.
Shrine N, Izquierdo AG, Chen J, Packer R, Hall RJ, Guyatt AL, Batini C, Thompson RJ, Pavuluri C, Malik V, Hobbs BD, Moll M, Kim W, Tal-Singer R, Bakke P, Fawcett KA, John C, Coley K, Piga NN, Pozarickij A, Lin K, Millwood IY, Chen Z, Li L; China Kadoorie Biobank Collaborative Group; Wijnant SRA, Lahousse L, Brusselle G, Uitterlinden AG, Manichaikul A, Oelsner EC, Rich SS, Barr RG, Kerr SM, Vitart V, Brown MR, Wielscher M, Imboden M, Jeong A, Bartz TM, Gharib SA, Flexeder C, Karrasch S, Gieger C, Peters A, Stubbe B, Hu X, Ortega VE, Meyers DA, Bleecker ER, Gabriel SB, Gupta N, Smith AV, Luan J, Zhao JH, Hansen AF, Langhammer A, Willer C, Bhatta L, Porteous D, Smith BH, Campbell A, Sofer T, Lee J, Daviglus ML, Yu B, Lim E, Xu H, O'Connor GT, Thareja G, Albagha OME; Qatar Genome Program Research (QGPR) Consortium; Suhre K, Granell R, Faquih TO, Hiemstra PS, Slats AM, Mullin BH, Hui J, James A, Beilby J, Patasova K, Hysi P, Koskela JT, Wyss AB, Jin J, Sikdar S, Lee M, May-Wilson S, Pirastu N, Kentistou KA, Joshi PK, Timmers PRHJ, Williams AT, Free RC, Wang X, Morrison JL, Gilliland FD, Chen Z, Wang CA, Foong RE, Harris SE, Taylor A, Redmond P, Cook JP, Mahajan A, Lind L, Palviainen T,… See abstract for full author list ➔ Shrine N, et al. Nat Genet. 2023 Mar;55(3):410-422. doi: 10.1038/s41588-023-01314-0. Epub 2023 Mar 13. Nat Genet. 2023. PMID: 36914875 Free PMC article.
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. ...Individual variants showed heterogeneity across ancestries, age and smoking groups, and collectively as a genetic risk score showed …
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. . …
Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration.
Mikami Y, Grubb BR, Rogers TD, Dang H, Asakura T, Kota P, Gilmore RC, Okuda K, Morton LC, Sun L, Chen G, Wykoff JA, Ehre C, Vilar J, van Heusden C, Livraghi-Butrico A, Gentzsch M, Button B, Stutts MJ, Randell SH, O'Neal WK, Boucher RC. Mikami Y, et al. Sci Transl Med. 2023 Jun 7;15(699):eabo7728. doi: 10.1126/scitranslmed.abo7728. Epub 2023 Jun 7. Sci Transl Med. 2023. PMID: 37285404
Consistent with requirements for luminal O(2), airway epithelia surrounding mucus plugs in chronic obstructive pulmonary disease (COPD) lungs are hypoxic. Despite these observations, the effects of chronic hypoxia (CH) on airway epithelia …
Consistent with requirements for luminal O(2), airway epithelia surrounding mucus plugs in chronic obstructive pulmonary …
Hedgehog pathway and its inhibitors in chronic obstructive pulmonary disease (COPD).
Lahmar Z, Ahmed E, Fort A, Vachier I, Bourdin A, Bergougnoux A. Lahmar Z, et al. Pharmacol Ther. 2022 Dec;240:108295. doi: 10.1016/j.pharmthera.2022.108295. Epub 2022 Oct 1. Pharmacol Ther. 2022. PMID: 36191777 Review.
COPD affects millions of people and is now ranked as the third leading cause of death worldwide. This largely untreatable chronic airway disease results in irreversible destruction of lung architecture. ...Genetic susceptibility is most likely involved as the …
COPD affects millions of people and is now ranked as the third leading cause of death worldwide. This largely untreatable chronic air …
Chronic obstructive pulmonary disease and lung cancer: inter-relationships.
Biswas A, Mehta HJ, Folch EE. Biswas A, et al. Curr Opin Pulm Med. 2018 Mar;24(2):152-160. doi: 10.1097/MCP.0000000000000451. Curr Opin Pulm Med. 2018. PMID: 29210751 Review.
PURPOSE OF REVIEW: Chronic obstructive pulmonary disease (COPD) is a well established risk factor for lung cancer. ...RECENT FINDINGS: There is an ever-growing bundle of evidence that suggests a close association between persistent chronic infla …
PURPOSE OF REVIEW: Chronic obstructive pulmonary disease (COPD) is a well established risk factor for lung cance …
Long Noncoding Transcriptome in Chronic Obstructive Pulmonary Disease.
Devadoss D, Long C, Langley RJ, Manevski M, Nair M, Campos MA, Borchert G, Rahman I, Chand HS. Devadoss D, et al. Am J Respir Cell Mol Biol. 2019 Dec;61(6):678-688. doi: 10.1165/rcmb.2019-0184TR. Am J Respir Cell Mol Biol. 2019. PMID: 31486667 Free PMC article. Review.
Chronic airway inflammation from recurring exposures to noxious environmental stimuli results in a progressive and irreversible airflow limitation and the lung parenchymal damage that characterizes chronic obstructive pulmonary disease (COPD). . …
Chronic airway inflammation from recurring exposures to noxious environmental stimuli results in a progressive and irreversible airfl …
Associations of combined phenotypic ageing and genetic risk with incidence of chronic respiratory diseases in the UK Biobank: a prospective cohort study.
Wang T, Duan W, Jia X, Huang X, Liu Y, Meng F, Ni C. Wang T, et al. Eur Respir J. 2024 Feb 22;63(2):2301720. doi: 10.1183/13993003.01720-2023. Print 2024 Feb. Eur Respir J. 2024. PMID: 38061785 Free PMC article.
BACKGROUND: Accelerated biological ageing has been associated with an increased risk of several chronic respiratory diseases. However, the associations between phenotypic age, a new biological age indicator based on clinical chemistry biomarkers, and common chronic …
BACKGROUND: Accelerated biological ageing has been associated with an increased risk of several chronic respiratory diseases. However …
Blood Gene Expression and Immune Cell Subtypes Associated with Chronic Obstructive Pulmonary Disease Exacerbations.
Ryu MH, Yun JH, Morrow JD, Saferali A, Castaldi P, Chase R, Stav M, Xu Z, Barjaktarevic I, Han M, Labaki W, Huang YJ, Christenson S, O'Neal W, Bowler R, Sin DD, Freeman CM, Curtis JL, Hersh CP. Ryu MH, et al. Am J Respir Crit Care Med. 2023 Aug 1;208(3):247-255. doi: 10.1164/rccm.202301-0085OC. Am J Respir Crit Care Med. 2023. PMID: 37286295
Rationale: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPDs) are associated with a significant disease burden. ...In COPDGene, the number of prospective exacerbations in patients with COPD (Global Initiative for Chronic …
Rationale: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPDs) are associated with a signifi …
798 results