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Page 1
A Detailed Dosimetric Analysis of Spinal Cord Tolerance in High-Dose Spine Radiosurgery.
Katsoulakis E, Jackson A, Cox B, Lovelock M, Yamada Y. Katsoulakis E, et al. Int J Radiat Oncol Biol Phys. 2017 Nov 1;99(3):598-607. doi: 10.1016/j.ijrobp.2017.05.053. Int J Radiat Oncol Biol Phys. 2017. PMID: 29280455
OBJECTIVE: Dose-volume tolerance of the spinal cord (SC) in spinal stereotactic radiosurgery (SRS) is difficult to define because radiation myelitis rates are low, and published reports document cases of myelopathy but do not account for the total number of patients …
OBJECTIVE: Dose-volume tolerance of the spinal cord (SC) in spinal stereotactic radiosurgery (SRS) is difficult to define because radiati …
Predictive Factors Associated With Radiation Myelopathy in Pediatric Patients With Cancer: A PENTEC Comprehensive Review.
Cooper BT, Mayo CS, Milano MT, Olch AJ, Oh C, Keating GF, Hallstrom A, Constine LS, Laack NN. Cooper BT, et al. Int J Radiat Oncol Biol Phys. 2024 Jun 1;119(2):494-506. doi: 10.1016/j.ijrobp.2023.12.020. Epub 2024 Feb 6. Int J Radiat Oncol Biol Phys. 2024. PMID: 38323945 Review.
PURPOSE: Radiation myelitis (RM) is a rare complication of radiation therapy (RT). ...
PURPOSE: Radiation myelitis (RM) is a rare complication of radiation therapy (RT). ...
Non-compressive myelopathy: clinical and radiological study.
Prabhakar S, Syal P, Singh P, Lal V, Khandelwal N, Das CP. Prabhakar S, et al. Neurol India. 1999 Dec;47(4):294-9. Neurol India. 1999. PMID: 10625902 Free article.
Acute transverse myelitis (ATM) was the commonest (31) followed by Vit B12 deficiency myelopathy (8), primary progressive multiple sclerosis (5), hereditary spastic paraplegia (3), tropical spastic paraplegia (2), subacute necrotising myelitis (1), radiation myelitis …
Acute transverse myelitis (ATM) was the commonest (31) followed by Vit B12 deficiency myelopathy (8), primary progressive multiple sclerosis …
Clinical outcome and morbidity in pediatric patients with nasopharyngeal cancer treated with chemoradiotherapy.
Sahai P, Mohanti BK, Sharma A, Thakar A, Bhasker S, Kakkar A, Sharma MC, Upadhyay AD. Sahai P, et al. Pediatr Blood Cancer. 2017 Feb;64(2):259-266. doi: 10.1002/pbc.26240. Epub 2016 Sep 29. Pediatr Blood Cancer. 2017. PMID: 27681956
Xerostomia, hypothyroidism, dental caries, neck fibrosis, trismus, and dysphagia were the common late effects in survivors. Radiation myelitis was observed in one patient. CONCLUSIONS: Treatment with neoadjuvant chemotherapy followed by concurrent chemoradiat …
Xerostomia, hypothyroidism, dental caries, neck fibrosis, trismus, and dysphagia were the common late effects in survivors. Radiation …
Proton therapy (PT) combined with concurrent chemotherapy for locally advanced non-small cell lung cancer with negative driver genes.
Jin Y, Shimizu S, Li Y, Yao Y, Liu X, Si H, Sakurai H, Xiao W. Jin Y, et al. Radiat Oncol. 2023 Nov 16;18(1):189. doi: 10.1186/s13014-023-02372-8. Radiat Oncol. 2023. PMID: 37974211 Free PMC article.
No statistical differences were observed at each time point (P > 0.05).The OS rates for the first to third years in both groups were as follows: 100%, 88.2%, 76.4% for the proton group vs. 100%, 91.4%, 46.3% for the X-ray group. ...CONCLUSION: There were no significant …
No statistical differences were observed at each time point (P > 0.05).The OS rates for the first to third years in both groups we …
Variation in radiation sensitivity and repair kinetics in different parts of the spinal cord.
Adamus-Górka M, Brahme A, Mavroidis P, Lind BK. Adamus-Górka M, et al. Acta Oncol. 2008;47(5):928-36. doi: 10.1080/02841860701864668. Acta Oncol. 2008. PMID: 18568487
MATERIAL AND METHODS: In the present study, the relative seriality model was fitted to two different datasets of clinical radiation myelitis concerning cervical spinal cord after treating 248 patients for head and neck cancer and thoracic spinal cord after treating …
MATERIAL AND METHODS: In the present study, the relative seriality model was fitted to two different datasets of clinical radiation …
Twice-a-day radiation therapy for cancer of the head and neck.
Wang CC, Blitzer PH, Suit HD. Wang CC, et al. Cancer. 1985 May 1;55(9 Suppl):2100-4. doi: 10.1002/1097-0142(19850501)55:9+<2100::aid-cncr2820551411>3.0.co;2-a. Cancer. 1985. PMID: 3919925
Acute mucosal reactions are generally more severe than those produced by QD continuous radiation therapy, but the duration of symptoms is shorter. Late effects on the normal tissues, as observed during the 4-year follow-up period, show no undue subcutaneous or mucosal reac …
Acute mucosal reactions are generally more severe than those produced by QD continuous radiation therapy, but the duration of symptoms is sh …
Radiation myelopathy in over-irradiated patients: MR imaging findings.
Alfonso ER, De Gregorio MA, Mateo P, Escó R, Bascón N, Morales F, Bellosta R, López P, Gimeno M, Roca M, Villavieja JL. Alfonso ER, et al. Eur Radiol. 1997;7(3):400-4. doi: 10.1007/s003300050174. Eur Radiol. 1997. PMID: 9087365

In all cases MRI was negative for neurologic lesions in the acute phase ( < 90 days from irradiation; Radiation Therapy Oncology Group scoring system). Late signs of radiation myelitis manifested as high-intensity signals on T2-weighted images in th

…

In all cases MRI was negative for neurologic lesions in the acute phase ( < 90 days from irradiation; Radiation Therapy Oncology Group

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Experience with dose escalation using CHARTWEL (continuous hyperfractionated accelerated radiotherapy weekend less) in non-small-cell lung cancer.
Saunders MI, Rojas A, Lyn BE, Pigott K, Powell M, Goodchild K, Hoskin PJ, Phillips H, Verma N. Saunders MI, et al. Br J Cancer. 1998 Nov;78(10):1323-8. doi: 10.1038/bjc.1998.678. Br J Cancer. 1998. PMID: 9823973 Free PMC article. Clinical Trial.
Acute and late morbidity with a CHARTWEL (CHART WeekEnd Less) schedule of 54 Gy in 16 days was compared with that observed with 60 Gy in 18 days in patients with locally advanced NSCLC. ...Early radiation pneumonitis was not increased but, after 6 months, there was a highe …
Acute and late morbidity with a CHARTWEL (CHART WeekEnd Less) schedule of 54 Gy in 16 days was compared with that observed with 60 Gy …
Spinal cord constraints in the era of high-precision radiotherapy : Retrospective analysis of 62 spinal/paraspinal lesions with possible infringements of spinal cord constraints within a minimal volume.
Zschaeck S, Wust P, Graf R, Wlodarczyk W, Schild R, Thieme AH, Weihrauch M, Budach V, Ghadjar P. Zschaeck S, et al. Strahlenther Onkol. 2017 Jul;193(7):561-569. doi: 10.1007/s00066-017-1138-5. Epub 2017 May 2. Strahlenther Onkol. 2017. PMID: 28466154 English.
OBJECTIVE: Current constraints aim to minimize the risk of radiation myelitis by the use of restrictive maximal spinal cord doses, commonly 50 Gy. ...Dose drop-off was steep in both groups. Median overall survival was 17 months. No radiation myelitis o …
OBJECTIVE: Current constraints aim to minimize the risk of radiation myelitis by the use of restrictive maximal spinal cord do …
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