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Quoted phrase not found in phrase index: "Recurrent Childhood Central Nervous System Embryonal Neoplasm"
Page 1
EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection.
Capper D, Reifenberger G, French PJ, Schweizer L, Weller M, Touat M, Niclou SP, Euskirchen P, Haberler C, Hegi ME, Brandner S, Le Rhun E, Rudà R, Sanson M, Tabatabai G, Sahm F, Wen PY, Wesseling P, Preusser M, van den Bent MJ. Capper D, et al. Neuro Oncol. 2023 May 4;25(5):813-826. doi: 10.1093/neuonc/noad008. Neuro Oncol. 2023. PMID: 36632791 Free PMC article.
For many systemic cancers, targeted treatments are a part of the standard of care, however, the predictive significance of most of these targets in central nervous system (CNS) tumors remains less well-studied. ...For targeted treatment of CNS tumors w …
For many systemic cancers, targeted treatments are a part of the standard of care, however, the predictive significance of most of th …
Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.
Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M. Fangusaro J, et al. Lancet Oncol. 2019 Jul;20(7):1011-1022. doi: 10.1016/S1470-2045(19)30277-3. Epub 2019 May 28. Lancet Oncol. 2019. PMID: 31151904 Free PMC article. Clinical Trial.
BACKGROUND: Paediatric low-grade glioma is the most common CNS tumour of childhood. Although overall survival is good, disease often recurs. ...Patients aged 3-21 years with a Lansky or Karnofsky performance score greater than 60 and the presence of recurrent …
BACKGROUND: Paediatric low-grade glioma is the most common CNS tumour of childhood. Although overall survival is good, disease often …
Temozolomide with irinotecan versus temozolomide, irinotecan plus bevacizumab for recurrent medulloblastoma of childhood: Report of a COG randomized Phase II screening trial.
Levy AS, Krailo M, Chi S, Villaluna D, Springer L, Williams-Hughes C, Fouladi M, Gajjar A. Levy AS, et al. Pediatr Blood Cancer. 2021 Aug;68(8):e29031. doi: 10.1002/pbc.29031. Epub 2021 Apr 12. Pediatr Blood Cancer. 2021. PMID: 33844469 Free PMC article. Clinical Trial.
BACKGROUND: Approximately 30% of children with medulloblastoma (MB) experience recurrence, which is usually incurable. This study compared the overall survival (OS) of patients receiving temozolomide (TMZ) and irinotecan with that of patients receiving TMZ, irinotecan, and …
BACKGROUND: Approximately 30% of children with medulloblastoma (MB) experience recurrence, which is usually incurable. This study com …
Childhood-onset craniopharyngioma: latest insights into pathology, diagnostics, treatment, and follow-up.
Bogusz A, Müller HL. Bogusz A, et al. Expert Rev Neurother. 2018 Oct;18(10):793-806. doi: 10.1080/14737175.2018.1528874. Epub 2018 Oct 4. Expert Rev Neurother. 2018. PMID: 30257123 Review.
Childhood-onset craniopharyngiomas are rare embryonic tumors of low-grade histological malignancy. ...Overall and progression-free survival rates are not associated with the degree of surgical resection. However, reduced overall survival rates were observed in patie …
Childhood-onset craniopharyngiomas are rare embryonic tumors of low-grade histological malignancy. ...Overall and progression-free su …
Long-term outcomes and late effects for childhood and young adulthood intracranial germinomas.
Acharya S, DeWees T, Shinohara ET, Perkins SM. Acharya S, et al. Neuro Oncol. 2015 May;17(5):741-6. doi: 10.1093/neuonc/nou311. Epub 2014 Nov 23. Neuro Oncol. 2015. PMID: 25422317 Free PMC article.
BACKGROUND: Pediatric and young adult central nervous system (CNS) germinomas have favorable cure rates. ...Kaplan Meier survival analysis was performed on 5-year survivors of childhood CNS germinomatous germ cell tumors (GGCTs) and nonge …
BACKGROUND: Pediatric and young adult central nervous system (CNS) germinomas have favorable cure rates. ...Kaplan Meie …
BMI1 is a therapeutic target in recurrent medulloblastoma.
Bakhshinyan D, Venugopal C, Adile AA, Garg N, Manoranjan B, Hallett R, Wang X, Mahendram S, Vora P, Vijayakumar T, Subapanditha M, Singh M, Kameda-Smith MM, Qazi M, McFarlane N, Mann A, Ajani OA, Yarascavitch B, Ramaswamy V, Farooq H, Morrissy S, Cao L, Sydorenko N, Baiazitov R, Du W, Sheedy J, Weetall M, Moon YC, Lee CS, Kwiecien JM, Delaney KH, Doble B, Cho YJ, Mitra S, Kaplan D, Taylor MD, Davis TW, Singh SK. Bakhshinyan D, et al. Oncogene. 2019 Mar;38(10):1702-1716. doi: 10.1038/s41388-018-0549-9. Epub 2018 Oct 22. Oncogene. 2019. PMID: 30348991
Medulloblastoma (MB) is the most frequent malignant pediatric brain tumor, representing 20% of newly diagnosed childhood central nervous system malignancies. Although advances in multimodal therapy yielded a 5-year survivorship of 80%, MB still account …
Medulloblastoma (MB) is the most frequent malignant pediatric brain tumor, representing 20% of newly diagnosed childhood central …
Recurrent pediatric central nervous system low-grade gliomas: the role of surveillance neuroimaging in asymptomatic children.
Udaka YT, Yeh-Nayre LA, Amene CS, VandenBerg SR, Levy ML, Crawford JR. Udaka YT, et al. J Neurosurg Pediatr. 2013 Feb;11(2):119-26. doi: 10.3171/2012.10.PEDS12307. Epub 2012 Nov 16. J Neurosurg Pediatr. 2013. PMID: 23157391
OBJECT: Pediatric low-grade glioma (LGG) is the most common brain tumor of childhood. Except for the known association of gross-total resection and improved survival rates, relatively little is known about the clinical and radiographic predictors of recurrent …
OBJECT: Pediatric low-grade glioma (LGG) is the most common brain tumor of childhood. Except for the known association of gross-total …
Liquid biopsy for pediatric diffuse midline glioma: a review of circulating tumor DNA and cerebrospinal fluid tumor DNA.
Azad TD, Jin MC, Bernhardt LJ, Bettegowda C. Azad TD, et al. Neurosurg Focus. 2020 Jan 1;48(1):E9. doi: 10.3171/2019.9.FOCUS19699. Neurosurg Focus. 2020. PMID: 31896079 Free PMC article. Review.
Diffuse midline glioma (DMG) is a highly malignant childhood tumor with an exceedingly poor prognosis and limited treatment options. The majority of these tumors harbor somatic mutations in genes encoding histone variants. These recurrent mutations correlate with tr …
Diffuse midline glioma (DMG) is a highly malignant childhood tumor with an exceedingly poor prognosis and limited treatment options. …
Cytogenetic analysis in the examination of solid tumors in children.
Mertens F, Mandahl N, Mitelman F, Heim S. Mertens F, et al. Pediatr Hematol Oncol. 1994 Jul-Aug;11(4):361-77. doi: 10.3109/08880019409140536. Pediatr Hematol Oncol. 1994. PMID: 7947009 Review.
Although pediatric solid tumors are cytogenetically less well characterized than childhood leukemias, an understanding of the role of chromosomal changes in the development of these neoplasms is emerging. ...Double minute chromosomes or homogeneously staining region …
Although pediatric solid tumors are cytogenetically less well characterized than childhood leukemias, an understanding of the role of …
Blood-brain barrier disruption with low-intensity pulsed ultrasound for the treatment of pediatric brain tumors: a review and perspectives.
Beccaria K, Canney M, Bouchoux G, Puget S, Grill J, Carpentier A. Beccaria K, et al. Neurosurg Focus. 2020 Jan 1;48(1):E10. doi: 10.3171/2019.10.FOCUS19726. Neurosurg Focus. 2020. PMID: 31896084 Review.
Pediatric brain tumors are the most common solid tumor and the first cause of cancer death in childhood, adolescence, and young adulthood. Current treatments are far from optimal in most of these tumors and the prognosis remains dismal for many of them. ...The safety and f …
Pediatric brain tumors are the most common solid tumor and the first cause of cancer death in childhood, adolescence, and young adult …
43 results