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Quoted phrase not found in phrase index: "Recurrent Metastatic Merkel Cell Carcinoma"
Page 1
Neoadjuvant Nivolumab for Patients With Resectable Merkel Cell Carcinoma in the CheckMate 358 Trial.
Topalian SL, Bhatia S, Amin A, Kudchadkar RR, Sharfman WH, Lebbé C, Delord JP, Dunn LA, Shinohara MM, Kulikauskas R, Chung CH, Martens UM, Ferris RL, Stein JE, Engle EL, Devriese LA, Lao CD, Gu J, Li B, Chen T, Barrows A, Horvath A, Taube JM, Nghiem P. Topalian SL, et al. J Clin Oncol. 2020 Aug 1;38(22):2476-2487. doi: 10.1200/JCO.20.00201. Epub 2020 Apr 23. J Clin Oncol. 2020. PMID: 32324435 Free PMC article. Clinical Trial.
PURPOSE: Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer commonly driven by the Merkel cell polyomavirus (MCPyV). ...Among 33 radiographically evaluable patients who underwent surgery, 18 (54.5%) had tumor reductions 30%. Responses …
PURPOSE: Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer commonly driven by the Merkel cell …
Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial.
Kim S, Wuthrick E, Blakaj D, Eroglu Z, Verschraegen C, Thapa R, Mills M, Dibs K, Liveringhouse C, Russell J, Caudell JJ, Tarhini A, Markowitz J, Kendra K, Wu R, Chen DT, Berglund A, Michael L, Aoki M, Wang MH, Hamaidi I, Cheng P, de la Iglesia J, Slebos RJ, Chung CH, Knepper TC, Moran-Segura CM, Nguyen JV, Perez BA, Rose T, Harrison L, Messina JL, Sondak VK, Tsai KY, Khushalani NI, Brohl AS. Kim S, et al. Lancet. 2022 Sep 24;400(10357):1008-1019. doi: 10.1016/S0140-6736(22)01659-2. Epub 2022 Sep 12. Lancet. 2022. PMID: 36108657 Free PMC article. Clinical Trial.
BACKGROUND: Merkel cell carcinoma is among the most aggressive and lethal of primary skin cancers, with a high rate of distant metastasis. Anti-programmed death receptor 1 (anti-PD-1) and programmed death ligand 1 (PD-L1) monotherapy is currently standard of …
BACKGROUND: Merkel cell carcinoma is among the most aggressive and lethal of primary skin cancers, with a high rate of …
Adjuvant immunotherapy with nivolumab versus observation in completely resected Merkel cell carcinoma (ADMEC-O): disease-free survival results from a randomised, open-label, phase 2 trial.
Becker JC, Ugurel S, Leiter U, Meier F, Gutzmer R, Haferkamp S, Zimmer L, Livingstone E, Eigentler TK, Hauschild A, Kiecker F, Hassel JC, Mohr P, Fluck M, Thomas I, Garzarolli M, Grimmelmann I, Drexler K, Spillner AN, Eckhardt S, Schadendorf D; DeCOG. Becker JC, et al. Lancet. 2023 Sep 2;402(10404):798-808. doi: 10.1016/S0140-6736(23)00769-9. Epub 2023 Jul 11. Lancet. 2023. PMID: 37451295 Clinical Trial.
BACKGROUND: Merkel cell carcinoma (MCC) is an immunogenic but aggressive skin cancer. ...Stratification factors (stage, age, sex) were balanced across the nivolumab (n=118) and internal control group (observation, n=61); adjuvant radiotherapy was more …
BACKGROUND: Merkel cell carcinoma (MCC) is an immunogenic but aggressive skin cancer. ...Stratification factors (stage, …
Merkel Cell Carcinoma Therapeutic Update.
Cassler NM, Merrill D, Bichakjian CK, Brownell I. Cassler NM, et al. Curr Treat Options Oncol. 2016 Jul;17(7):36. doi: 10.1007/s11864-016-0409-1. Curr Treat Options Oncol. 2016. PMID: 27262710 Free PMC article. Review.
Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor of the skin. ...At the same time, high-throughput sequencing studies have demonstrated significant differences in the mutational profiles of tumors with and without the Merkel …
Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor of the skin. ...At the same time, high-throug …
Treatment of Advanced Merkel Cell Carcinoma: Current Therapeutic Options and Novel Immunotherapy Approaches.
Femia D, Prinzi N, Anichini A, Mortarini R, Nichetti F, Corti F, Torchio M, Peverelli G, Pagani F, Maurichi A, Mattavelli I, Milione M, Bedini N, Corti A, Di Bartolomeo M, de Braud F, Pusceddu S. Femia D, et al. Target Oncol. 2018 Oct;13(5):567-582. doi: 10.1007/s11523-018-0585-y. Target Oncol. 2018. PMID: 30073632 Review.
Advanced Merkel cell carcinoma (MCC) is a very aggressive, rare neuroendocrine tumor of the skin with a high frequency of locoregional recurrence and metastasis, and a high mortality rate. ...More recently, immunotherapy agents such as avelumab, pembro …
Advanced Merkel cell carcinoma (MCC) is a very aggressive, rare neuroendocrine tumor of the skin with a high frequency …
Merkel Cell Carcinoma of the Eyelids (Clinical-Histological Study).
Krásný J, Šach J, Kolín V, Zikmund J. Krásný J, et al. Cesk Slov Oftalmol. 2019 Spring;74(5):198-205. doi: 10.31348/2018/5/5. Cesk Slov Oftalmol. 2019. PMID: 31234633 Free article. English.
AIM: To get acquainted with the issues of Merkel cell carcinoma (MCC) when the eyelid is affected and with its surgical solution. ...Essential importance for successful treatment is a sufficiently radical excision supported by histological verification and a …
AIM: To get acquainted with the issues of Merkel cell carcinoma (MCC) when the eyelid is affected and with its surgical …
Adjuvant radiotherapy for Merkel cell carcinoma: A systematic review and meta-analysis.
Petrelli F, Ghidini A, Torchio M, Prinzi N, Trevisan F, Dallera P, De Stefani A, Russo A, Vitali E, Bruschieri L, Costanzo A, Seghezzi S, Ghidini M, Varricchio A, Cabiddu M, Barni S, de Braud F, Pusceddu S. Petrelli F, et al. Radiother Oncol. 2019 May;134:211-219. doi: 10.1016/j.radonc.2019.02.015. Epub 2019 Feb 28. Radiother Oncol. 2019. PMID: 31005218
Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous malignancy with a high propensity for local recurrence and regional and distant metastases. ...Meta-regression analysis showed that high Newcastle-Ottawa scale scores, stage I-II MCC …
Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous malignancy with a high propensity for local recurrenc …
Merkel cell carcinoma of the head and neck.
Suárez C, Rodrigo JP, Ferlito A, Devaney KO, Rinaldo A. Suárez C, et al. Oral Oncol. 2004 Sep;40(8):773-9. doi: 10.1016/j.oraloncology.2003.11.005. Oral Oncol. 2004. PMID: 15288830 Review.
Merkel cell carcinoma (MCC) is a rare neuroendocrine neoplasm of the skin. ...Finally, factors generally associated with survival are the stage of disease at presentation, distant recurrence usually being the most adverse predictor of survival.. …
Merkel cell carcinoma (MCC) is a rare neuroendocrine neoplasm of the skin. ...Finally, factors generally associated wit …
Merkel cell carcinoma in Taiwan: A series of 24 cases and literature review.
Chang JW, Chang YY, Huang YL, Lo YF, Ho TY, Huang YT, Chen HW, Yeh CN, Wu CE. Chang JW, et al. Medicine (Baltimore). 2019 Oct;98(42):e17538. doi: 10.1097/MD.0000000000017538. Medicine (Baltimore). 2019. PMID: 31626116 Free PMC article.
Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine carcinoma of the skin. ...Salvage surgery for loco-regional recurrence lengthened the survival time and possibly cured recurrent MCC. ...
Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine carcinoma of the skin. ...Salvage surgery fo …
Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation.
Stakaitytė G, Nwogu N, Dobson SJ, Knight LM, Wasson CW, Salguero FJ, Blackbourn DJ, Blair GE, Mankouri J, Macdonald A, Whitehouse A. Stakaitytė G, et al. J Virol. 2018 Jan 2;92(2):e00940-17. doi: 10.1128/JVI.00940-17. Print 2018 Jan 15. J Virol. 2018. PMID: 29093086 Free PMC article.
Motility is dependent on the activities of integrin receptors and Rho family GTPases, resulting in the remodeling of the actin cytoskeleton and formation of various motile actin-based protrusions. Merkel cell carcinoma (MCC) is an aggressive skin cancer with …
Motility is dependent on the activities of integrin receptors and Rho family GTPases, resulting in the remodeling of the actin cytoskeleton …
70 results