A phase II trial of high-dose methotrexate in previously untreated children and adolescents with high-risk unresectable or metastatic rhabdomyosarcoma.
Pappo AS, Bowman LC, Furman WL, Rao BN, Kun LE, Jenkins JJ, Crom WR, Luo X, Kaste SC, Avery L, Meyer WH, Shapiro DN, Crist WM.
Pappo AS, et al.
J Pediatr Hematol Oncol. 1997 Sep-Oct;19(5):438-42. doi: 10.1097/00043426-199709000-00006.
J Pediatr Hematol Oncol. 1997.
PMID: 9329466
Clinical Trial.
PURPOSE: The outcome for children with advanced-stage rhabdomyosarcoma remains poor with contemporary treatment regimens. Evaluation of new drugs is important to improve clinical outcome. Because methotrexate has shown promising activity in the treatment of patients with …
PURPOSE: The outcome for children with advanced-stage rhabdomyosarcoma remains poor with contemporary treatment regimens. Evaluation of new …