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Quoted phrase not found in phrase index: "Recurrent Aplastic Anemia"
Page 1
Severe aplastic anemia: allogeneic bone marrow transplantation as first-line treatment.
Georges GE, Doney K, Storb R. Georges GE, et al. Blood Adv. 2018 Aug 14;2(15):2020-2028. doi: 10.1182/bloodadvances.2018021162. Blood Adv. 2018. PMID: 30108110 Free PMC article. Review.
Treatment of severe aplastic anemia has improved significantly over the past 4 decades. ...Implementation of this first-line treatment strategy will provide patients with severe aplastic anemia the best chance of long-term disease-free survival....
Treatment of severe aplastic anemia has improved significantly over the past 4 decades. ...Implementation of this first-line t …
Pathophysiology, diagnosis, and treatment of paroxysmal nocturnal hemoglobinuria: a review.
Devalet B, Mullier F, Chatelain B, Dogné JM, Chatelain C. Devalet B, et al. Eur J Haematol. 2015 Sep;95(3):190-8. doi: 10.1111/ejh.12543. Epub 2015 Mar 26. Eur J Haematol. 2015. PMID: 25753400 Review.
Patients experience intravascular hemolysis, smooth muscle dystonia, renal failure, arterial and pulmonary hypertension, recurrent infectious diseases and an increased risk of notably dreadful thrombotic complications. ...Efforts have been recently performed to improve the …
Patients experience intravascular hemolysis, smooth muscle dystonia, renal failure, arterial and pulmonary hypertension, recurrent in …
Eltrombopag in aplastic anemia.
Desmond R, Townsley DM, Dunbar C, Young NS. Desmond R, et al. Semin Hematol. 2015 Jan;52(1):31-7. doi: 10.1053/j.seminhematol.2014.10.002. Epub 2014 Oct 31. Semin Hematol. 2015. PMID: 25578417 Free PMC article. Review.
The treatment of aplastic anemia is currently with immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and cyclosporine, to which two thirds of patients respond. ...A recent trial has shown that eltrombopag, a thrombopoeitin mimetic, is efficacious in …
The treatment of aplastic anemia is currently with immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and cycl …
Temozolomide-related hematologic toxicity.
Scaringi C, De Sanctis V, Minniti G, Enrici RM. Scaringi C, et al. Onkologie. 2013;36(7-8):444-9. doi: 10.1159/000353752. Epub 2013 Jul 8. Onkologie. 2013. PMID: 23921765 Review.
Temozolomide (TMZ) is an oral alkylating agent used for the treatment of recurrent or newly diagnosed malignant gliomas with significant survival benefit. ...However severe hematologic adverse events (HAEs), including myelodysplastic syndrome and aplastic anemia …
Temozolomide (TMZ) is an oral alkylating agent used for the treatment of recurrent or newly diagnosed malignant gliomas with signific …
Niraparib plus bevacizumab versus niraparib alone for platinum-sensitive recurrent ovarian cancer (NSGO-AVANOVA2/ENGOT-ov24): a randomised, phase 2, superiority trial.
Mirza MR, Åvall Lundqvist E, Birrer MJ, dePont Christensen R, Nyvang GB, Malander S, Anttila M, Werner TL, Lund B, Lindahl G, Hietanen S, Peen U, Dimoula M, Roed H, Ør Knudsen A, Staff S, Krog Vistisen A, Bjørge L, Mäenpää JU; AVANOVA investigators. Mirza MR, et al. Lancet Oncol. 2019 Oct;20(10):1409-1419. doi: 10.1016/S1470-2045(19)30515-7. Epub 2019 Aug 29. Lancet Oncol. 2019. PMID: 31474354 Clinical Trial.
AVANOVA2 compared niraparib and bevacizumab versus niraparib alone as definitive treatment for platinum-sensitive recurrent ovarian cancer. METHODS: This open-label, randomised, phase 2, superiority trial in 15 university hospitals in Denmark, Sweden, Finland, Norway, and …
AVANOVA2 compared niraparib and bevacizumab versus niraparib alone as definitive treatment for platinum-sensitive recurrent ovarian c …
Molecular pathogenesis of acquired aplastic anemia.
Boddu PC, Kadia TM. Boddu PC, et al. Eur J Haematol. 2019 Feb;102(2):103-110. doi: 10.1111/ejh.13182. Epub 2018 Dec 18. Eur J Haematol. 2019. PMID: 30380171 Review.
The application of next-generation sequencing (NGS) has enhanced our understanding of the genetic landscape in acquired aplastic anemia (AA). Parallel progress has been in addressing aspects underlying immune dysregulation in disease pathogenesis. ...The detection o …
The application of next-generation sequencing (NGS) has enhanced our understanding of the genetic landscape in acquired aplastic a …
Clonal hematopoiesis: Pre-cancer PLUS.
Silver AJ, Jaiswal S. Silver AJ, et al. Adv Cancer Res. 2019;141:85-128. doi: 10.1016/bs.acr.2018.12.003. Epub 2019 Jan 14. Adv Cancer Res. 2019. PMID: 30691686 Review.
Many of the genes most commonly mutated in clonal hematopoiesis are also recurrently mutated in leukemia, genes such as DNMT3A, TET2, ASXL1, JAK2, and TP53. ...Clonal hematopoiesis is correlated with several other diseases as well, including diabetes, chronic pulmonary dis …
Many of the genes most commonly mutated in clonal hematopoiesis are also recurrently mutated in leukemia, genes such as DNMT3A, TET2, …
Immunosuppressive therapy in severe aplastic anemia.
Patel BA, Townsley DM, Scheinberg P. Patel BA, et al. Semin Hematol. 2022 Jan;59(1):21-29. doi: 10.1053/j.seminhematol.2022.01.002. Epub 2022 Jan 19. Semin Hematol. 2022. PMID: 35491055
Severe aplastic anemia, a disease characterized by pancytopenia and a hypocellular marrow, is treatable by either immunosuppressive therapy (IST) or hematopoietic stem cell transplant. ...
Severe aplastic anemia, a disease characterized by pancytopenia and a hypocellular marrow, is treatable by either immunosuppre …
Hepatitis-associated aplastic anemia.
Brown KE, Tisdale J, Barrett AJ, Dunbar CE, Young NS. Brown KE, et al. N Engl J Med. 1997 Apr 10;336(15):1059-64. doi: 10.1056/NEJM199704103361504. N Engl J Med. 1997. PMID: 9091802 Free article.
BACKGROUND: Hepatitis-associated aplastic anemia is a variant of aplastic anemia in which aplastic anemia follows an acute attack of hepatitis. ...All patients were treated with antithymocyte globulin and cyclosporine. RESULTS: Ten patien …
BACKGROUND: Hepatitis-associated aplastic anemia is a variant of aplastic anemia in which aplastic ane …
Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase 2 trial.
DeZern AE, Eapen M, Wu J, Talano JA, Solh M, Dávila Saldaña BJ, Karanes C, Horwitz ME, Mallhi K, Arai S, Farhadfar N, Hexner E, Westervelt P, Antin JH, Deeg HJ, Leifer E, Brodsky RA, Logan BR, Horowitz MM, Jones RJ, Pulsipher MA. DeZern AE, et al. Lancet Haematol. 2022 Sep;9(9):e660-e669. doi: 10.1016/S2352-3026(22)00206-X. Epub 2022 Jul 27. Lancet Haematol. 2022. PMID: 35907408 Free PMC article. Clinical Trial.
BACKGROUND: Relapsed severe aplastic anaemia is a marrow failure disorder with high morbidity and mortality. ...This study aimed to understand the 1-year overall survival in patients with relapsed or refractory severe aplastic anaemia after haploidenti …
BACKGROUND: Relapsed severe aplastic anaemia is a marrow failure disorder with high morbidity and mortality. ...This study aim …
243 results