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Quoted phrase not found in phrase index: "Recurrent Dedifferentiated Chordoma"
Page 1
Chordoma.
Ulici V, Hart J. Ulici V, et al. Arch Pathol Lab Med. 2022 Mar 1;146(3):386-395. doi: 10.5858/arpa.2020-0258-RA. Arch Pathol Lab Med. 2022. PMID: 34319396 Free article. Review.
OBJECTIVE.-: To summarize the clinical and pathologic findings of the various types of chordoma (conventional chordoma, dedifferentiated chordoma, and poorly differentiated chordoma), the differential diagnosis, and recent advances in molecular …
OBJECTIVE.-: To summarize the clinical and pathologic findings of the various types of chordoma (conventional chordoma, ded …
Chordoma: Genetics and Contemporary Management.
Desai R, Pelargos PE, Dunn IF. Desai R, et al. Int J Mol Sci. 2024 May 28;25(11):5877. doi: 10.3390/ijms25115877. Int J Mol Sci. 2024. PMID: 38892063 Free PMC article. Review.
Chordomas, arising from notochord remnants, are rare neoplasms with aggressive growth patterns despite their histologically low-grade nature. ...Diagnosis relies on advanced imaging and biopsy confirmation due to overlapping features with chondrosarcoma. The WHO classifica …
Chordomas, arising from notochord remnants, are rare neoplasms with aggressive growth patterns despite their histologically low-grade …
Skull Base Chordomas and Chondrosarcomas.
Kremenevski N, Schlaffer SM, Coras R, Kinfe TM, Graillon T, Buchfelder M. Kremenevski N, et al. Neuroendocrinology. 2020;110(9-10):836-847. doi: 10.1159/000509386. Epub 2020 Jun 15. Neuroendocrinology. 2020. PMID: 32541136 Free article. Review.
Both entities are characterized by infiltration and destruction of the surrounding bone and soft tissue and a high locoregional recurrence rate. Chondrosarcomas, when treated with similar complex strategies, display a much better prognosis than chordomas. ...Chor …
Both entities are characterized by infiltration and destruction of the surrounding bone and soft tissue and a high locoregional recurrenc …
Dedifferentiated Chordoma: Clinicopathologic and Molecular Characteristics With Integrative Analysis.
Hung YP, Diaz-Perez JA, Cote GM, Wejde J, Schwab JH, Nardi V, Chebib IA, Deshpande V, Selig MK, Bredella MA, Rosenberg AE, Nielsen GP. Hung YP, et al. Am J Surg Pathol. 2020 Sep;44(9):1213-1223. doi: 10.1097/PAS.0000000000001501. Am J Surg Pathol. 2020. PMID: 32427623
Dedifferentiated chordoma is a rare chordoma subtype characterized by a high-grade sarcoma juxtaposed to conventional chordoma. ...The dedifferentiated component shows loss of brachyury and cytokeratin staining and harbors recurrent TP53 …
Dedifferentiated chordoma is a rare chordoma subtype characterized by a high-grade sarcoma juxtaposed to conventional …
Clinico-Genomic Profiling of Conventional and Dedifferentiated Chondrosarcomas Reveals TP53 Mutation to Be Associated with Worse Outcomes.
Denu RA, Yang RK, Lazar AJ, Patel SS, Lewis VO, Roszik J, Livingston JA, Wang WL, Shaw KR, Ratan R, Zarzour MA, Bird J, Raza S, Akdemir KC, Rodon Ahnert J, Subbiah V, Patel S, Conley AP. Denu RA, et al. Clin Cancer Res. 2023 Dec 1;29(23):4844-4852. doi: 10.1158/1078-0432.CCR-23-1703. Clin Cancer Res. 2023. PMID: 37747813
EXPERIMENTAL DESIGN: We included 93 patients with conventional and dedifferentiated chondrosarcoma for which there were available clinical next-generation sequencing data. ...RESULTS: IDH1 and IDH2 mutations are prevalent in chondrosarcoma (50.5%), more common in chondrosa …
EXPERIMENTAL DESIGN: We included 93 patients with conventional and dedifferentiated chondrosarcoma for which there were available cli …
Aggressive Chordomas: Clinical Outcome of 13 Patients.
Mavrogenis AF, Angelini A, Panagopoulos GN, Pala E, Calabrò T, Igoumenou VG, Katzouraki G, Megaloikonomos PD, Pneumaticos SG, Papagelopoulos PJ, Ruggieri P. Mavrogenis AF, et al. Orthopedics. 2017 Mar 1;40(2):e248-e254. doi: 10.3928/01477447-20161108-02. Epub 2016 Nov 14. Orthopedics. 2017. PMID: 27841927
Mean follow-up was 43 months (range, 8-131 months). Rates of local recurrence, metastasis, and death were evaluated. At the last follow-up, all patients had local recurrence at a mean of 13 months (range, 5-22 months). Histologic examination of recurrent tumo …
Mean follow-up was 43 months (range, 8-131 months). Rates of local recurrence, metastasis, and death were evaluated. At the last foll …
Chordoma: the nonsarcoma primary bone tumor.
Chugh R, Tawbi H, Lucas DR, Biermann JS, Schuetze SM, Baker LH. Chugh R, et al. Oncologist. 2007 Nov;12(11):1344-50. doi: 10.1634/theoncologist.12-11-1344. Oncologist. 2007. PMID: 18055855 Free article. Review.
Chordomas are divided into conventional, chondroid, and dedifferentiated types. ...This variant accounts for 5%-15% of all chordomas and up to 33% of cranial chordomas. Dedifferentiation or sarcomatous transformation occurs in 2%-8% of chordo …
Chordomas are divided into conventional, chondroid, and dedifferentiated types. ...This variant accounts for 5%-15% of all …
Chordoma: a systematic review of the epidemiology and clinical prognostic factors predicting progression-free and overall survival.
Bakker SH, Jacobs WCH, Pondaag W, Gelderblom H, Nout RA, Dijkstra PDS, Peul WC, Vleggeert-Lankamp CLA. Bakker SH, et al. Eur Spine J. 2018 Dec;27(12):3043-3058. doi: 10.1007/s00586-018-5764-0. Epub 2018 Sep 15. Eur Spine J. 2018. PMID: 30220042
PROGNOSTIC FACTORS: Statistically significant adverse prognostic factors predicting progression-free and overall survival include female sex, older age, bigger tumour size, increasing extent of tumour invasion, non-total resection, presence of metastasis, local recurrence, …
PROGNOSTIC FACTORS: Statistically significant adverse prognostic factors predicting progression-free and overall survival include female sex …
Chordomas: A review with emphasis on their pathophysiology, pathology, molecular biology, and genetics.
Karpathiou G, Dumollard JM, Dridi M, Dal Col P, Barral FG, Boutonnat J, Peoc'h M. Karpathiou G, et al. Pathol Res Pract. 2020 Sep;216(9):153089. doi: 10.1016/j.prp.2020.153089. Epub 2020 Jun 29. Pathol Res Pract. 2020. PMID: 32825957 Review.
Dedifferentiated and poorly differentiated forms can be observed. Moreover, a grading scale for chordomas has been proposed. ...In this review, the histological, immunohistochemical, molecular, and clinical data of chordomas are discussed....
Dedifferentiated and poorly differentiated forms can be observed. Moreover, a grading scale for chordomas has been proposed. . …
Treatment of dedifferentiated chordoma: a retrospective study from a large volume cancer center.
Nachwalter RN, Rothrock RJ, Katsoulakis E, Gounder MM, Boland PJ, Bilsky MH, Laufer I, Schmitt AM, Yamada Y, Higginson DS. Nachwalter RN, et al. J Neurooncol. 2019 Sep;144(2):369-376. doi: 10.1007/s11060-019-03239-3. Epub 2019 Jul 23. J Neurooncol. 2019. PMID: 31338785 Free PMC article.
OBJECTIVE: Dedifferentiated chordomas (DC) are genetically and clinically distinct from conventional chordomas (CC), exhibiting frequent SMARCB1 alterations and a more aggressive clinical course. ...CONCLUSION: DC patients exhibit significantly higher rates o …
OBJECTIVE: Dedifferentiated chordomas (DC) are genetically and clinically distinct from conventional chordomas (CC), ex …
24 results