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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1990 4
1991 1
1992 1
1993 2
1995 1
1996 1
1997 2
1998 4
2001 1
2002 2
2003 2
2004 1
2005 2
2006 2
2008 3
2009 1
2010 8
2011 9
2012 4
2013 7
2014 8
2015 4
2016 10
2017 9
2018 6
2019 10
2020 14
2021 18
2022 13
2023 17
2024 11

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158 results

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Page 1
Corticosteroids for acute bacterial meningitis.
Brouwer MC, McIntyre P, Prasad K, van de Beek D. Brouwer MC, et al. Cochrane Database Syst Rev. 2015 Sep 12;2015(9):CD004405. doi: 10.1002/14651858.CD004405.pub5. Cochrane Database Syst Rev. 2015. PMID: 26362566 Free PMC article. Review.
Nine studies were performed in low-income countries and 16 in high-income countries.Corticosteroids were associated with a non-significant reduction in mortality (17.8% versus 19.9%; risk ratio (RR) 0.90, 95% confidence interval (CI) 0.80 to 1.01, P value = 0.07). A similar non-s …
Nine studies were performed in low-income countries and 16 in high-income countries.Corticosteroids were associated with a non-significant r …
Pediatric recurrent fever and autoinflammation from the perspective of an allergist/immunologist.
Broderick L, Hoffman HM. Broderick L, et al. J Allergy Clin Immunol. 2020 Nov;146(5):960-966.e2. doi: 10.1016/j.jaci.2020.09.019. Epub 2020 Sep 28. J Allergy Clin Immunol. 2020. PMID: 33002514 Free PMC article. Review.
Given the presentation of fevers, rashes, and mucosal symptoms observed in many of these syndromes, patients are likely to present to an allergist/immunologist. ...To address this challenge, we review the history of the medical approach to fever, current diagnostic paradig …
Given the presentation of fevers, rashes, and mucosal symptoms observed in many of these syndromes, patients are likely to present to …
ROSAH syndrome mimicking chronic uveitis.
Fardeau C, Alafaleq M, Dhaenens CM, Dollfus H, Koné-Paut I, Grunewald O, Morel JB, Titah C, Saadoun D, Lazeran PO, Meunier I. Fardeau C, et al. Clin Genet. 2023 Apr;103(4):453-458. doi: 10.1111/cge.14286. Epub 2022 Dec 30. Clin Genet. 2023. PMID: 36543582
To suggest a unique missense variant candidate based on long-term ophthalmological changes and associated systemic signs described in five patients from two unrelated families affected by an autosomal dominant multi-systemic disorder including Retinal dystrophy, Optic nerve oedem …
To suggest a unique missense variant candidate based on long-term ophthalmological changes and associated systemic signs described in five p …
Role of glucocorticoids in Kawasaki disease.
Miura M. Miura M. Int J Rheum Dis. 2018 Jan;21(1):70-75. doi: 10.1111/1756-185X.13209. Epub 2017 Nov 3. Int J Rheum Dis. 2018. PMID: 29105310 Review.
Although treatment with intravenous immunoglobulin (IVIg) with aspirin is the standard of care for children with Kawasaki disease (KD), 15-20% of patients fail to respond and experience persistent or recurrent fever after completion of IVIg administration. These IVI …
Although treatment with intravenous immunoglobulin (IVIg) with aspirin is the standard of care for children with Kawasaki disease (KD), 15-2 …
A20 Haploinsufficiency in East Asia.
Kadowaki T, Kadowaki S, Ohnishi H. Kadowaki T, et al. Front Immunol. 2021 Nov 26;12:780689. doi: 10.3389/fimmu.2021.780689. eCollection 2021. Front Immunol. 2021. PMID: 34899744 Free PMC article. Review.
Because the phenotypes associated with HA20 are broad, with different severities observed even among individuals in the same family with identical mutations, it has been assumed that the symptoms of HA20 may depend on genetic background and environmental factors. In this r …
Because the phenotypes associated with HA20 are broad, with different severities observed even among individuals in the same family w …
Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes.
Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS Jr, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG; Overcoming COVID-19 Investigators. Son MBF, et al. N Engl J Med. 2021 Jul 1;385(1):23-34. doi: 10.1056/NEJMoa2102605. Epub 2021 Jun 16. N Engl J Med. 2021. PMID: 34133855 Free PMC article.
Secondary outcomes included the components of the primary outcome, the receipt of adjunctive treatment (glucocorticoids in patients not already receiving glucocorticoids on day 0, a biologic, or a second dose of IVIG) on or after day 1, and persistent or recurrent fever …
Secondary outcomes included the components of the primary outcome, the receipt of adjunctive treatment (glucocorticoids in patients not alre …
Association of Clinical Phenotypes in Haploinsufficiency A20 (HA20) With Disrupted Domains of A20.
Chen Y, Ye Z, Chen L, Qin T, Seidler U, Tian D, Xiao F. Chen Y, et al. Front Immunol. 2020 Sep 23;11:574992. doi: 10.3389/fimmu.2020.574992. eCollection 2020. Front Immunol. 2020. PMID: 33101300 Free PMC article. Review.
The main manifestations of HA20 patients were recurrent oral ulcers (70%), recurrent fever (42%), gastrointestinal ulcers (40%), skin lesion (38%), genital ulcers (36%), and musculoskeletal disorders (34%). ...
The main manifestations of HA20 patients were recurrent oral ulcers (70%), recurrent fever (42%), gastrointestinal ulcers (40% …
Corticosteroids for acute bacterial meningitis.
Brouwer MC, McIntyre P, Prasad K, van de Beek D. Brouwer MC, et al. Cochrane Database Syst Rev. 2013 Jun 4;(6):CD004405. doi: 10.1002/14651858.CD004405.pub4. Cochrane Database Syst Rev. 2013. PMID: 23733364 Updated. Review.
Corticosteroids were associated with a non-significant reduction in mortality (17.8% versus 19.9%; risk ratio (RR) 0.90, 95% confidence interval (CI) 0.80 to 1.01, P = 0.07). A similar non-significant reduction in mortality was observed in adults receiving corticosteroids …
Corticosteroids were associated with a non-significant reduction in mortality (17.8% versus 19.9%; risk ratio (RR) 0.90, 95% confidence inte …
Children and Adults with PFAPA Syndrome: Similarities and Divergences in a Real-Life Clinical Setting.
Sicignano LL, Rigante D, Moccaldi B, Massaro MG, Delli Noci S, Patisso I, Capozio G, Verrecchia E, Manna R. Sicignano LL, et al. Adv Ther. 2021 Feb;38(2):1078-1093. doi: 10.1007/s12325-020-01576-8. Epub 2020 Dec 14. Adv Ther. 2021. PMID: 33315168
A strong efficacy of corticosteroids in controlling the pediatric syndrome was observed, but response rates to steroids were less brilliant in adults. ...CONCLUSIONS: A linear conformity of the PFAPA syndrome has been observed between pediatric and adult patients. P …
A strong efficacy of corticosteroids in controlling the pediatric syndrome was observed, but response rates to steroids were less bri …
The phenotype and genotype of Chinese adult patients with NLRP3-associated autoinflammatory disease.
Wu N, Wu D, Miao J, Zhao M, Wang Y, Yu W, Shen M. Wu N, et al. Clin Rheumatol. 2023 Oct;42(10):2841-2848. doi: 10.1007/s10067-023-06679-5. Epub 2023 Jun 27. Clin Rheumatol. 2023. PMID: 37368056
RESULTS: The median age of disease onset was 16 (0-46) years old, and adult-onset was observed in 4 patients (25%). The median time of diagnosis delay was 20 (0-39) years. Five patients (31.3%) had family history of similar symptoms. The most common clinical manifestations …
RESULTS: The median age of disease onset was 16 (0-46) years old, and adult-onset was observed in 4 patients (25%). The median time o …
158 results